Elina Akalestou
@elina-ak.bsky.social
Lecturer/Assistant Prof in University Of Leicester. Honorary lecturer in Imperial College. Focus on sodium-glucose transport and bariatric surgery. Opening a Tiki Bar is my plan B.
Pinned
Elina Akalestou
@elina-ak.bsky.social
· Jul 25
Further to reducing blood sugar in #T2D, SGLT2 inhibitors improve insulin sensitivity, reduce inflammation and boost antioxidant defences: new roles in immune modulation and metabolic balance link.springer.com/article/10.1... 🔓
Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels - Diabetologia
Aims/hypothesis Despite recent therapeutic advances, achieving optimal glycaemic control remains a challenge in managing type 2 diabetes. Sodium–glucose cotransporter 2 (SGLT2) inhibitors have emerged...
link.springer.com
My first senior author paper came out this month, and I could not be more proud of the 3 leading authors, all students in my lab. This work shows how vital it is to continue working towards repurposing drugs for multimorbidity, especially if oral, low cost, low side effects. Sequel coming out soon!
My first senior author paper came out this month, and I could not be more proud of the 3 leading authors, all students in my lab. This work shows how vital it is to continue working towards repurposing drugs for multimorbidity, especially if oral, low cost, low side effects. Sequel coming out soon!
Further to reducing blood sugar in #T2D, SGLT2 inhibitors improve insulin sensitivity, reduce inflammation and boost antioxidant defences: new roles in immune modulation and metabolic balance link.springer.com/article/10.1... 🔓
Effects of SGLT2 ablation or inhibition on corticosterone secretion in high-fat-fed mice: exploring a nexus with cytokine levels - Diabetologia
Aims/hypothesis Despite recent therapeutic advances, achieving optimal glycaemic control remains a challenge in managing type 2 diabetes. Sodium–glucose cotransporter 2 (SGLT2) inhibitors have emerged...
link.springer.com
July 25, 2025 at 6:34 AM
My first senior author paper came out this month, and I could not be more proud of the 3 leading authors, all students in my lab. This work shows how vital it is to continue working towards repurposing drugs for multimorbidity, especially if oral, low cost, low side effects. Sequel coming out soon!
Reposted by Elina Akalestou
If you’re not angry, you’re not paying attention.
🎥: Time, 💬 Greta Thunberg
🎥: Time, 💬 Greta Thunberg
June 11, 2025 at 1:51 PM
If you’re not angry, you’re not paying attention.
🎥: Time, 💬 Greta Thunberg
🎥: Time, 💬 Greta Thunberg
Reposted by Elina Akalestou
boycott-israel.org/boycott.html
Have a read, see what you can eliminate from your life. Start from home, ask your company, check your lab.
Have a read, see what you can eliminate from your life. Start from home, ask your company, check your lab.
Boycott Israel - A Simple Boycott List
A simple boycott list of Israeli and global firms active in Israel, guiding purchases to pressure the government and uphold international law.
boycott-israel.org
May 23, 2025 at 7:49 AM
boycott-israel.org/boycott.html
Have a read, see what you can eliminate from your life. Start from home, ask your company, check your lab.
Have a read, see what you can eliminate from your life. Start from home, ask your company, check your lab.
Reposted by Elina Akalestou
May the fourth be with you USA.
May 4, 2025 at 9:52 PM
May the fourth be with you USA.
Reposted by Elina Akalestou
Breaking news: A new lawsuit seeks to challenge the National Institutes of Health’s decisions to abruptly terminate hundreds of grants, totaling more than $2.4 billion, over the past month. scim.ag/3DZnylL
Lawsuit aims to broadly overturn NIH’s grant terminations
Multiple groups and NIH-funded scientists challenge agency’s decision as arbitrary and capricious
scim.ag
April 2, 2025 at 9:35 PM
Breaking news: A new lawsuit seeks to challenge the National Institutes of Health’s decisions to abruptly terminate hundreds of grants, totaling more than $2.4 billion, over the past month. scim.ag/3DZnylL
We used to offer sanctuary to Ukrainian, Palestinian and Afghan scientists, and now to the scientists from the leader of the free world. Unfathomable.
A French University is funding a Safe Place For Science program meant to recruit scientists who cannot continue their work in the US. www.univ-amu.fr/fr/public/a...
March 14, 2025 at 10:41 PM
We used to offer sanctuary to Ukrainian, Palestinian and Afghan scientists, and now to the scientists from the leader of the free world. Unfathomable.
Is this a reasonable way to work?
February 21, 2025 at 6:57 PM
Is this a reasonable way to work?
The unseen, terrible consequences of Trump's ax on indirect costs. Millions of research animals may die due to lack of funding to keep them alive, yet anti-vivisectionists would call this a long-term win. Go figure.
Exclusively from @science.org : ‘Death by ax.’ Fate of millions of research animals at stake in NIH payments lawsuit | Science | AAAS www.science.org/content/arti...
‘Death by ax.’ Fate of millions of research animals at stake in NIH payments lawsuit
Rodent and monkey facilities imperiled by Trump plan to cut overhead payments
www.science.org
February 21, 2025 at 6:50 PM
The unseen, terrible consequences of Trump's ax on indirect costs. Millions of research animals may die due to lack of funding to keep them alive, yet anti-vivisectionists would call this a long-term win. Go figure.
Reposted by Elina Akalestou
What the health & scientific world "have experienced in the past few weeks is like a death in the family. We are angry, shocked, & saddened, but we must not despair". This a telling account of what is happening in the #US, but I am saddened that the author felt it had to be written anonymously.
Anger, despair, and defiance from a voice within the US federal research system
People around the world are watching with disbelief as the new US government closes down its aid programme, withdraws from the World Health Organization (WHO) and the Paris agreement on climate change...
www.bmj.com
February 14, 2025 at 6:42 PM
What the health & scientific world "have experienced in the past few weeks is like a death in the family. We are angry, shocked, & saddened, but we must not despair". This a telling account of what is happening in the #US, but I am saddened that the author felt it had to be written anonymously.
Reposted by Elina Akalestou
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018.
Read more on #WomenInScienceDay: https://scim.ag/4hOUuvx
Read more on #WomenInScienceDay: https://scim.ag/4hOUuvx
February 11, 2025 at 5:10 PM
When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018.
Read more on #WomenInScienceDay: https://scim.ag/4hOUuvx
Read more on #WomenInScienceDay: https://scim.ag/4hOUuvx
Following our project grant from BHF Accelerator Award, our team had yet another success with the Van Geest Foundation Research Fund, ensuring our research can continue interrupted for at least another year🔬. Truly grateful and relieved for this, at a time that labs around the world are struggling.
February 11, 2025 at 1:07 PM
Following our project grant from BHF Accelerator Award, our team had yet another success with the Van Geest Foundation Research Fund, ensuring our research can continue interrupted for at least another year🔬. Truly grateful and relieved for this, at a time that labs around the world are struggling.
My doggie gets a lot more love from my lab colleagues than I do. Rightfully so :)
February 5, 2025 at 3:52 PM
My doggie gets a lot more love from my lab colleagues than I do. Rightfully so :)
Reposted by Elina Akalestou
So if I’m understanding today correctly, the world’s richest person Elon Musk, whom no one elected, is taking over federal payment systems and employee data while the federal employees who investigate and prosecute public corruption are being fired en masse.
January 31, 2025 at 8:26 PM
So if I’m understanding today correctly, the world’s richest person Elon Musk, whom no one elected, is taking over federal payment systems and employee data while the federal employees who investigate and prosecute public corruption are being fired en masse.
Optimal weather for a science gathering at the docklands
January 30, 2025 at 3:29 PM
Optimal weather for a science gathering at the docklands
Excellent gathering of companies and scientists at the Festival of Genomics and Biodata in ExCel London. Anyone else here?
January 30, 2025 at 2:27 PM
Excellent gathering of companies and scientists at the Festival of Genomics and Biodata in ExCel London. Anyone else here?
Reposted by Elina Akalestou
Unsolicited writing advice, no. #1108:
Don't fetishize antisocial behaviour, illness or addiction. Some writers have also been abusers, or alcoholics, or addicts, or mentally ill. None of these things made them better writers. If they were great, it was in spite of those things, not because of them.
Don't fetishize antisocial behaviour, illness or addiction. Some writers have also been abusers, or alcoholics, or addicts, or mentally ill. None of these things made them better writers. If they were great, it was in spite of those things, not because of them.
January 29, 2025 at 10:30 AM
Unsolicited writing advice, no. #1108:
Don't fetishize antisocial behaviour, illness or addiction. Some writers have also been abusers, or alcoholics, or addicts, or mentally ill. None of these things made them better writers. If they were great, it was in spite of those things, not because of them.
Don't fetishize antisocial behaviour, illness or addiction. Some writers have also been abusers, or alcoholics, or addicts, or mentally ill. None of these things made them better writers. If they were great, it was in spite of those things, not because of them.
Hello world! So happy I finally joined this Bluesky party. My lab and I love proteomics, drug repurposing and coffee. We also all have a thing for dogs.
January 29, 2025 at 12:38 PM
Hello world! So happy I finally joined this Bluesky party. My lab and I love proteomics, drug repurposing and coffee. We also all have a thing for dogs.
It has been 15 years since the last time I opened a new social media profile, is it like riding a bike?
January 24, 2025 at 8:54 AM
It has been 15 years since the last time I opened a new social media profile, is it like riding a bike?