Ed Campbell
edcampbelllab.bsky.social
Ed Campbell
@edcampbelllab.bsky.social
Studying HIV infection, inflammation, particularly inflammasomes in vivo, and ancient retroviral genes that do cool things. Loyola University Chicago, Stritch School of Medicine

https://sites.google.com/view/campbell-lab-loyola/home

Great article by a friend and amazing scientist
April 10, 2025 at 2:13 AM
Reposted by Ed Campbell
Most inflammasome mutations in humans are gain of function, which complicates the question of why we have these molecular machines. @sunnyshinlab.bsky.social et al provide strong evidence that we need inflammasomes to prevent Salmonella infection. A must read! elifesciences.org/articles/90107
Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
Analysis of inflammasome responses in human macrophages reveals that inflammatory caspases and pyroptotic factors control Salmonella replication primarily within the cytosol and also within vacuoles.
elifesciences.org
April 2, 2025 at 10:24 PM
Reposted by Ed Campbell
ICYMI (especially if you work in Democratic politics):

Cutting cancer research is one of the things Americans are most worried about.

And one of the things they’ve heard the least about. According to polls from @navigatorsurvey.bsky.social:
1/
March 23, 2025 at 6:03 PM
Reposted by Ed Campbell
Results from our AntiRetroviral Therapy for Alzheimer's Disease (ART-AD) clinical trial are available online today and will be included in the inaugural issue of npj Dementia.

rdcu.be/edfwq
A Phase IIa clinical trial to evaluate the effects of anti-retroviral therapy in Alzheimer’s disease (ART-AD)
npj Dementia - A Phase IIa clinical trial to evaluate the effects of anti-retroviral therapy in Alzheimer’s disease (ART-AD)
rdcu.be
March 12, 2025 at 12:49 PM
Reposted by Ed Campbell
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.
jamanetwork.com
March 10, 2025 at 2:15 PM
Amazing scientist I got the chance to meet with during a seminar at UW. Recall the inspired conversation and questions to this day
March 3, 2025 at 5:27 PM
Nailed it….I hope she spiked the ball
Must watch speech by neuroscientist Kailyn Price at a HHS rally protesting funding cuts to science.

"Cutting indirect costs is like telling a football team to work with only the players.

No lights for the field, no physical therapists for the players, no water for the showers."
February 20, 2025 at 2:06 PM
Reposted by Ed Campbell
Good summary of what’s at stake with these NIH funding cuts here
🛟 That last-ditch chemo trial your family member was hoping to be in
🥙 The investigation of a food-borne illness outbreak in the next town over
🧠The study looking for preventable causes of Alzheimer’s
🧪The assurance that TAXPAYER-PAID-FOR studies & data collection see the light of day
February 15, 2025 at 4:58 PM
Reposted by Ed Campbell
This is the most relevant article to NIH and research cuts I’ve seen.

Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”

globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
February 9, 2025 at 9:58 PM
In a sea of hand-ringers, tantrums, middle-grounders and a tsunami of thread based explanations of indirect costs, @jkagan1.bsky.social is slaying….tip of the hat sir
History is the only true teacher.

History tells us that all knowledge in medical textbooks, all medical procedures, all genetic tests to predict disease, all hopes for a cure for cancer, derive from one source.

University/Non-profit research.
February 9, 2025 at 10:07 PM
“Red states have universities too,” one Trump official, speaking on the condition of anonymity because they were not authorized to speak to the press, wrote in a message.

That truth needs to be the narrative. Every person that starts with “certainly there is room to improve” loses science aura….
February 8, 2025 at 8:23 PM
Reposted by Ed Campbell
This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research?
All of them.
February 8, 2025 at 4:09 AM
Looks like a great opportunity to learn from outstanding researchers! They don’t accept full professors, but if I were still an undergraduate, I’d take a real serious look at this!
Applications for undergraduate summer studentships @wwiem-qub.bsky.social are now open. We would love to host enthusiastic students from anywhere in the world in Belfast! 👨‍🔬👩‍🔬🧪💊🌎 Details: www.qub.ac.uk/research-cen...
Summer Student Programme | Wellcome-Wolfson Institute For Experimental Medicine | Queen's University Belfast
www.qub.ac.uk
February 3, 2025 at 6:08 PM
Reposted by Ed Campbell
I am confident that scientific societies will play an unusually important role in the coming years. If you are a microbiologist of any kind, please consider joining @asm.org if you haven't already. There are many ways to get involved, including advocacy.
To learn more:
asm.org/About-ASM/Vo...
Volunteer With ASM | Overview
ASM volunteer opportunities range from speaking with legislators about funding research during ASM's annual Hill Day, to writing articles for asm.org, to serving on committees and the Board of Directo...
asm.org
January 23, 2025 at 9:21 PM
Is there is no way to bookmark a post on Bluesky? If we want to bring science Twitter here, this seems like a must. Am I missing something? Please help
January 16, 2025 at 2:59 AM