Dynamic42
@dynamic42.bsky.social
Recreating human physiology in vitro for better therapies and disease research without animal experiments. Posting about news and insights from the organ-on-chip world. Learn more about us here --> https://dynamic42.com/
Noreen gives insights into her work for the RUBIN alliance "ATHANA".
She is talking about the assays she uses and the model she is building together with the lung team.
She is talking about the assays she uses and the model she is building together with the lung team.
November 4, 2025 at 8:57 AM
Noreen gives insights into her work for the RUBIN alliance "ATHANA".
She is talking about the assays she uses and the model she is building together with the lung team.
She is talking about the assays she uses and the model she is building together with the lung team.
Do read-outs for #organonchip and #2D cell culture differ?
They don't! Why? Because the samples we can take from our organ models are very similar. We can look at the supernatants, at the cells during incubation but also extract the tissue afterward for downstream analysis.
They don't! Why? Because the samples we can take from our organ models are very similar. We can look at the supernatants, at the cells during incubation but also extract the tissue afterward for downstream analysis.
October 28, 2025 at 9:03 AM
Do read-outs for #organonchip and #2D cell culture differ?
They don't! Why? Because the samples we can take from our organ models are very similar. We can look at the supernatants, at the cells during incubation but also extract the tissue afterward for downstream analysis.
They don't! Why? Because the samples we can take from our organ models are very similar. We can look at the supernatants, at the cells during incubation but also extract the tissue afterward for downstream analysis.
⏳ Final reminder!
Bioinsights Live30 webinar TOMORROW: Organ-on-chip modeling for PDAC drug discovery
🗓 23 Oct | 🕔 5 pm CET
Don’t miss expert insights from Dynamic42 & HHU!
🔗 Register: zurl.co/t3mCz
#Webinar #OrganOnChip #DrugDiscovery
Bioinsights Live30 webinar TOMORROW: Organ-on-chip modeling for PDAC drug discovery
🗓 23 Oct | 🕔 5 pm CET
Don’t miss expert insights from Dynamic42 & HHU!
🔗 Register: zurl.co/t3mCz
#Webinar #OrganOnChip #DrugDiscovery
October 22, 2025 at 8:03 AM
⏳ Final reminder!
Bioinsights Live30 webinar TOMORROW: Organ-on-chip modeling for PDAC drug discovery
🗓 23 Oct | 🕔 5 pm CET
Don’t miss expert insights from Dynamic42 & HHU!
🔗 Register: zurl.co/t3mCz
#Webinar #OrganOnChip #DrugDiscovery
Bioinsights Live30 webinar TOMORROW: Organ-on-chip modeling for PDAC drug discovery
🗓 23 Oct | 🕔 5 pm CET
Don’t miss expert insights from Dynamic42 & HHU!
🔗 Register: zurl.co/t3mCz
#Webinar #OrganOnChip #DrugDiscovery
Discover how spheroids-on-chip are transforming preclinical cancer research! 🔬
Learn about modeling the PDAC tumor microenvironment & proof-of-concept data with SAHA.
📅 23 Oct 2025 | 5 pm CET
🔗 zurl.co/l9OXG
#CancerResearch #DrugDiscovery #Bioinsights
Learn about modeling the PDAC tumor microenvironment & proof-of-concept data with SAHA.
📅 23 Oct 2025 | 5 pm CET
🔗 zurl.co/l9OXG
#CancerResearch #DrugDiscovery #Bioinsights
October 14, 2025 at 8:02 AM
Discover how spheroids-on-chip are transforming preclinical cancer research! 🔬
Learn about modeling the PDAC tumor microenvironment & proof-of-concept data with SAHA.
📅 23 Oct 2025 | 5 pm CET
🔗 zurl.co/l9OXG
#CancerResearch #DrugDiscovery #Bioinsights
Learn about modeling the PDAC tumor microenvironment & proof-of-concept data with SAHA.
📅 23 Oct 2025 | 5 pm CET
🔗 zurl.co/l9OXG
#CancerResearch #DrugDiscovery #Bioinsights
Meet us at Scientist Vendor Discovery Day!
Get live insights into our organ-on-chip technology, a special preview of our #TME Kit and plenty of time to connect & exchange ideas!
Register now: zurl.co/0KY9k
#Scientist #organonchip #OoC #ScientistVendorDiscoveryDay
Get live insights into our organ-on-chip technology, a special preview of our #TME Kit and plenty of time to connect & exchange ideas!
Register now: zurl.co/0KY9k
#Scientist #organonchip #OoC #ScientistVendorDiscoveryDay
October 13, 2025 at 10:57 AM
Meet us at Scientist Vendor Discovery Day!
Get live insights into our organ-on-chip technology, a special preview of our #TME Kit and plenty of time to connect & exchange ideas!
Register now: zurl.co/0KY9k
#Scientist #organonchip #OoC #ScientistVendorDiscoveryDay
Get live insights into our organ-on-chip technology, a special preview of our #TME Kit and plenty of time to connect & exchange ideas!
Register now: zurl.co/0KY9k
#Scientist #organonchip #OoC #ScientistVendorDiscoveryDay
🚀 Join our Bioinsights Live30 webinar!
Organ-on-chip innovation for pancreatic cancer drug discovery
🗓 23 Oct 2025 | 🕔 5 pm CET
Speakers: Dynamic42 & Heinrich Heine University
Register here 👉 zurl.co/6lo3T
#OrganOnChip #DrugDiscovery #Webinar
Organ-on-chip innovation for pancreatic cancer drug discovery
🗓 23 Oct 2025 | 🕔 5 pm CET
Speakers: Dynamic42 & Heinrich Heine University
Register here 👉 zurl.co/6lo3T
#OrganOnChip #DrugDiscovery #Webinar
October 9, 2025 at 7:00 AM
🚀 Join our Bioinsights Live30 webinar!
Organ-on-chip innovation for pancreatic cancer drug discovery
🗓 23 Oct 2025 | 🕔 5 pm CET
Speakers: Dynamic42 & Heinrich Heine University
Register here 👉 zurl.co/6lo3T
#OrganOnChip #DrugDiscovery #Webinar
Organ-on-chip innovation for pancreatic cancer drug discovery
🗓 23 Oct 2025 | 🕔 5 pm CET
Speakers: Dynamic42 & Heinrich Heine University
Register here 👉 zurl.co/6lo3T
#OrganOnChip #DrugDiscovery #Webinar
We’re heading to ELRIG Drug Discovery 2025 in Liverpool on October 21–22! 🚀
Come meet us at booth #D14 where we’ll showcase our cutting-edge organ-on-chip technology.
Stop by and say hello. We’d love to connect at #ELRIGDD25!
#OrganonChip #OoC #CancerResearch
Come meet us at booth #D14 where we’ll showcase our cutting-edge organ-on-chip technology.
Stop by and say hello. We’d love to connect at #ELRIGDD25!
#OrganonChip #OoC #CancerResearch
October 8, 2025 at 12:23 PM
We’re heading to ELRIG Drug Discovery 2025 in Liverpool on October 21–22! 🚀
Come meet us at booth #D14 where we’ll showcase our cutting-edge organ-on-chip technology.
Stop by and say hello. We’d love to connect at #ELRIGDD25!
#OrganonChip #OoC #CancerResearch
Come meet us at booth #D14 where we’ll showcase our cutting-edge organ-on-chip technology.
Stop by and say hello. We’d love to connect at #ELRIGDD25!
#OrganonChip #OoC #CancerResearch
Does it always have to be a human #organonchip?
No, sometimes we also venture into different animals, such as Anne in one of her recent projects.
No, sometimes we also venture into different animals, such as Anne in one of her recent projects.
October 7, 2025 at 6:11 AM
Does it always have to be a human #organonchip?
No, sometimes we also venture into different animals, such as Anne in one of her recent projects.
No, sometimes we also venture into different animals, such as Anne in one of her recent projects.
🚀 Breakthrough in our #cancer-on-chip model!
Tom created a vasculature that grows into tumor spheroids overcoming previous matrix degradation challenges, he achieved direct tumor vascularization.
Want to learn how? Grab a spot in our Advanced Academy for next year!
Tom created a vasculature that grows into tumor spheroids overcoming previous matrix degradation challenges, he achieved direct tumor vascularization.
Want to learn how? Grab a spot in our Advanced Academy for next year!
October 1, 2025 at 6:25 AM
🚀 Breakthrough in our #cancer-on-chip model!
Tom created a vasculature that grows into tumor spheroids overcoming previous matrix degradation challenges, he achieved direct tumor vascularization.
Want to learn how? Grab a spot in our Advanced Academy for next year!
Tom created a vasculature that grows into tumor spheroids overcoming previous matrix degradation challenges, he achieved direct tumor vascularization.
Want to learn how? Grab a spot in our Advanced Academy for next year!
All prepped and ready to go! 🔬
Today we are hosting a workshop at University of Stuttgart, where participants will acquire the skills to integrate organ-on-chip technology in their research.
Looking forward to an eventful day! 🤗
#ooc #organonchip #education
Today we are hosting a workshop at University of Stuttgart, where participants will acquire the skills to integrate organ-on-chip technology in their research.
Looking forward to an eventful day! 🤗
#ooc #organonchip #education
September 30, 2025 at 8:07 AM
All prepped and ready to go! 🔬
Today we are hosting a workshop at University of Stuttgart, where participants will acquire the skills to integrate organ-on-chip technology in their research.
Looking forward to an eventful day! 🤗
#ooc #organonchip #education
Today we are hosting a workshop at University of Stuttgart, where participants will acquire the skills to integrate organ-on-chip technology in their research.
Looking forward to an eventful day! 🤗
#ooc #organonchip #education
Within the RUBIN alliance "ATHANA" Japhette is looking at new treatment options for #lung #aspergillosis using our lung-on-chip model. #organonchip
September 25, 2025 at 8:14 AM
Within the RUBIN alliance "ATHANA" Japhette is looking at new treatment options for #lung #aspergillosis using our lung-on-chip model. #organonchip
Join our Organ-on-Chip Workshop & Lecture Series at TU Dresden, on October 16!
Dive into the world of organ-on-chip technology and experience hands-on workshops and engaging lectures on research and industrial applications.
🚨 Secure one of our limited spots: zurl.co/lQmtU
#OrganOnChip#TUDresden
Dive into the world of organ-on-chip technology and experience hands-on workshops and engaging lectures on research and industrial applications.
🚨 Secure one of our limited spots: zurl.co/lQmtU
#OrganOnChip#TUDresden
September 24, 2025 at 1:56 PM
Join our Organ-on-Chip Workshop & Lecture Series at TU Dresden, on October 16!
Dive into the world of organ-on-chip technology and experience hands-on workshops and engaging lectures on research and industrial applications.
🚨 Secure one of our limited spots: zurl.co/lQmtU
#OrganOnChip#TUDresden
Dive into the world of organ-on-chip technology and experience hands-on workshops and engaging lectures on research and industrial applications.
🚨 Secure one of our limited spots: zurl.co/lQmtU
#OrganOnChip#TUDresden
We are excited to announce that our team is expanding with passionate minds who will strengthen our expertise in organ-on-chip technologies and share our mission to shape the future of drug development with human-relevant, ethical, and innovative solutions!
#dynamic42#organonchip
#dynamic42#organonchip
September 23, 2025 at 7:35 AM
We are excited to announce that our team is expanding with passionate minds who will strengthen our expertise in organ-on-chip technologies and share our mission to shape the future of drug development with human-relevant, ethical, and innovative solutions!
#dynamic42#organonchip
#dynamic42#organonchip
Meet us at #Ilmac in Basel!
You can find us at the #Axonlab international booth C212, where we’ll be showcasing our solutions, which will soon be available in Switzerland via Axonlab.
We look forward to connecting with the Swiss community. See you! 🇨🇭
#Dynamic42 #Innovation
You can find us at the #Axonlab international booth C212, where we’ll be showcasing our solutions, which will soon be available in Switzerland via Axonlab.
We look forward to connecting with the Swiss community. See you! 🇨🇭
#Dynamic42 #Innovation
September 17, 2025 at 6:31 AM
Meet us at #Ilmac in Basel!
You can find us at the #Axonlab international booth C212, where we’ll be showcasing our solutions, which will soon be available in Switzerland via Axonlab.
We look forward to connecting with the Swiss community. See you! 🇨🇭
#Dynamic42 #Innovation
You can find us at the #Axonlab international booth C212, where we’ll be showcasing our solutions, which will soon be available in Switzerland via Axonlab.
We look forward to connecting with the Swiss community. See you! 🇨🇭
#Dynamic42 #Innovation
Meet us at #EUROTOX2025 booth #A47 if you are interested in:
💊 Biochips without PDMS
🔬 High sample recovery
🦠 Infections models for all the microbes out there
💡 Capital-free tech & seamless workflows
🧫 Cancer models #TME
💊 Biochips without PDMS
🔬 High sample recovery
🦠 Infections models for all the microbes out there
💡 Capital-free tech & seamless workflows
🧫 Cancer models #TME
September 16, 2025 at 9:21 AM
Meet us at #EUROTOX2025 booth #A47 if you are interested in:
💊 Biochips without PDMS
🔬 High sample recovery
🦠 Infections models for all the microbes out there
💡 Capital-free tech & seamless workflows
🧫 Cancer models #TME
💊 Biochips without PDMS
🔬 High sample recovery
🦠 Infections models for all the microbes out there
💡 Capital-free tech & seamless workflows
🧫 Cancer models #TME
At #EUROTOX2025? Don’t miss Poster P19-17 today! Joanna presents our 3D perfused human liver model for DILI assessment using trovafloxacin & levofloxacin. Mimics liver microanatomy, drug dosing & more! #DILI #OrganOnChip
September 15, 2025 at 8:56 AM
At #EUROTOX2025? Don’t miss Poster P19-17 today! Joanna presents our 3D perfused human liver model for DILI assessment using trovafloxacin & levofloxacin. Mimics liver microanatomy, drug dosing & more! #DILI #OrganOnChip
Antibody Validation & Safety Testing with Organ-on-Chip
Tomorrow at #EUROTOX2025, our liver head Anne-Katrin Bothe presents a blood vessel & liver model for antibody validation with Sanofi.
Poster P17-05.
Tomorrow at #EUROTOX2025, our liver head Anne-Katrin Bothe presents a blood vessel & liver model for antibody validation with Sanofi.
Poster P17-05.
September 14, 2025 at 9:54 AM
Antibody Validation & Safety Testing with Organ-on-Chip
Tomorrow at #EUROTOX2025, our liver head Anne-Katrin Bothe presents a blood vessel & liver model for antibody validation with Sanofi.
Poster P17-05.
Tomorrow at #EUROTOX2025, our liver head Anne-Katrin Bothe presents a blood vessel & liver model for antibody validation with Sanofi.
Poster P17-05.
Key Features VII – Low Drug Adsorption: Biochip materials in organ models should be biocompatible, have low drug absorption, and no leaching to prevent altered dose-response curves & tissue growth issues.
September 11, 2025 at 7:44 AM
Key Features VII – Low Drug Adsorption: Biochip materials in organ models should be biocompatible, have low drug absorption, and no leaching to prevent altered dose-response curves & tissue growth issues.
When in Greece…
…do as the toxicologists do - sip wine, savor food, and chat about liver models! 🍷🍽️🧪
The team is gearing up for #EUROTOX2025 in Athens! 🇬🇷
Join us to explore antibody validation, safety testing, & liver toxicity models.
See you there!
…do as the toxicologists do - sip wine, savor food, and chat about liver models! 🍷🍽️🧪
The team is gearing up for #EUROTOX2025 in Athens! 🇬🇷
Join us to explore antibody validation, safety testing, & liver toxicity models.
See you there!
September 8, 2025 at 7:48 AM
When in Greece…
…do as the toxicologists do - sip wine, savor food, and chat about liver models! 🍷🍽️🧪
The team is gearing up for #EUROTOX2025 in Athens! 🇬🇷
Join us to explore antibody validation, safety testing, & liver toxicity models.
See you there!
…do as the toxicologists do - sip wine, savor food, and chat about liver models! 🍷🍽️🧪
The team is gearing up for #EUROTOX2025 in Athens! 🇬🇷
Join us to explore antibody validation, safety testing, & liver toxicity models.
See you there!
Tim is raising our #intestine-on-chip model to the next level by developing a primary cell-based model, including biochemical as well as electrical sensors to have real-time measurements insight the tissue & adds oxygen gradients for host-microbiota integration. #organonchip
September 2, 2025 at 8:22 AM
Tim is raising our #intestine-on-chip model to the next level by developing a primary cell-based model, including biochemical as well as electrical sensors to have real-time measurements insight the tissue & adds oxygen gradients for host-microbiota integration. #organonchip
Key features part VI – Multicellular Tissues
Organ-on-chip tech offers flexible, adaptable models for research. Scale from single to multicellular types, control experiments, and exclude cell types to study specific impacts.
Organ-on-chip tech offers flexible, adaptable models for research. Scale from single to multicellular types, control experiments, and exclude cell types to study specific impacts.
August 26, 2025 at 7:40 AM
Key features part VI – Multicellular Tissues
Organ-on-chip tech offers flexible, adaptable models for research. Scale from single to multicellular types, control experiments, and exclude cell types to study specific impacts.
Organ-on-chip tech offers flexible, adaptable models for research. Scale from single to multicellular types, control experiments, and exclude cell types to study specific impacts.
Immune evasion, dynamic drug application and angiogenesis…
…just some of the keywords Thomas mentioned when we talked to him about the exciting projects, he is currently working on within the cancer team here at Dynamic42.
…just some of the keywords Thomas mentioned when we talked to him about the exciting projects, he is currently working on within the cancer team here at Dynamic42.
August 21, 2025 at 6:27 AM
Immune evasion, dynamic drug application and angiogenesis…
…just some of the keywords Thomas mentioned when we talked to him about the exciting projects, he is currently working on within the cancer team here at Dynamic42.
…just some of the keywords Thomas mentioned when we talked to him about the exciting projects, he is currently working on within the cancer team here at Dynamic42.
Our body is always in motion blood vessels, lungs, intestines. Organ-on-chip applies stretch/strain to cells, influencing behavior via flow or mechanical deformation. This activates the mechanostimulatory complex, a key cellular sensor ignored in standard in vitro tests.
August 14, 2025 at 6:37 AM
Our body is always in motion blood vessels, lungs, intestines. Organ-on-chip applies stretch/strain to cells, influencing behavior via flow or mechanical deformation. This activates the mechanostimulatory complex, a key cellular sensor ignored in standard in vitro tests.
While looking for stem-cell-based PhD projects Joanna found her final topic #organonchip rather spontaneously. Not knowing what it was she start to read on it & was immediately captivated by the power of organ models & their promises for the future of biomedical research.
August 12, 2025 at 7:35 AM
While looking for stem-cell-based PhD projects Joanna found her final topic #organonchip rather spontaneously. Not knowing what it was she start to read on it & was immediately captivated by the power of organ models & their promises for the future of biomedical research.