Dr Jessica Otte, 🇨🇦 MD, CCFP, FCFP 🩺🌍🌱
banner
drotte.medsky.social
Dr Jessica Otte, 🇨🇦 MD, CCFP, FCFP 🩺🌍🌱
@drotte.medsky.social
Palliative care/family doc in Nanaimo, BC. Clinical Associate Prof, UBC Medicine

Focus: the intersection of Palliative Care + sustainability. Was @lessismoremedicine.❤️quaternary prevention, preventing overdiagnosis, goal-concordant EBM, choosing wisely.
RTVS programs = incredible. Saw that at the JCC talk today. As one who stopped remote practice, one reason was not feeling able to manage occasional critical cases with the skills/confidence required. That’s a big barrier to sustaining rural work.

RTVS could (does) make all the difference!!!
October 7, 2025 at 9:00 PM
Yes. Some are better than others. Many suggest things that conflict with others.
October 7, 2025 at 8:53 PM
good question...probably not. The mechanism is likely related to neurotransmitters and their post-synaptic receptors being down-regulated.

Our group has done a fair bit of work on this: www.ti.ubc.ca/2025/06/18/1... and www.ti.ubc.ca/2025/07/17/1... are our recent efforts.
Therapeutics Initiative | [156] Antidepressant withdrawal syndrome – Update
www.ti.ubc.ca
September 17, 2025 at 1:28 AM
. . . particularly in youth. I think tramadol carries a warning (in the USA anyway) of increased risk of suicide. We did not assess that in our paper - but none of the studies reported on it anyway. One has to look at population-level data and there are certainly a number of case reports that fit.
September 15, 2025 at 4:23 AM
I'm sorry you went through that, it must have been very frightening! Pharmacologically: the molecular structure and mechanism of action of tramadol, besides opioid-effect, is that of an SNRI (similar to venlafaxine). Increased suicidality can be a side effect of SSRI or SNRI antidepressants. . .
September 15, 2025 at 4:23 AM
tough! In Canada we don’t have “direct to consumer” marketing thankfully. People do see American TV ads but it is more the physicians who follow the myth that tramadol is “safer than opioids” who I suspect drive the prescribing trend. hopefully our article helps a bit
September 13, 2025 at 3:39 PM
that is a perfect summary! haha that is exactly what we found. Our inclusion of types/durations of pain and the durations of studies etc was perhaps overly broad, but there is so little out there that we decided it would be best to include it all.
September 13, 2025 at 5:58 AM
Critical thinking skills 101. How do you know something is “true”?

Kids need to be able to reason.
July 14, 2025 at 3:48 AM