drmichelleboyle.bsky.social
@drmichelleboyle.bsky.social
Reposted
The approved medication ruxolitinib dampens inflammatory responses to malaria and can enhance immune memory to the parasite in infected volunteers, supporting its potential as an adjunctive therapy to improve outcomes. #ScienceTranslationalMedicine https://scim.ag/44tu6TB
Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum
Adjunctive ruxolitinib reduces inflammatory response after experimental malaria challenge and enhances immune memory responses to reinfection.
scim.ag
December 1, 2025 at 5:05 PM
Reposted
This week's issue of #ScienceTranslationalMedicine has arrived!

A transcriptional signature could inform smarter antibiotic use in newborns with sepsis, an approved medication boosts anti-malaria immunity in volunteers, and more. https://scim.ag/43PsmE6
November 26, 2025 at 10:00 PM
So pleased to share our study of a host-directed therapy to boost malaria immunity.

Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum | Science Translational Medicine www.science.org/doi/10.1126/...
Adjunctive ruxolitinib attenuates inflammation and enhances immunity in volunteers experimentally infected with Plasmodium falciparum
Adjunctive ruxolitinib reduces inflammatory response after experimental malaria challenge and enhances immune memory responses to reinfection.
www.science.org
November 26, 2025 at 10:32 PM
Reposted
Excited to have our latest research published in @jem.org this week and also highlighted by @natrevimmunol.nature.com
@wehi-research.bsky.social @benjbroom.bsky.social
May 8, 2025 at 11:31 PM