Melanie Walter
@drmelaniew.bsky.social
Postdoc in the @thecesarelab.bsky.social 🧬 at Children's Medical Research Institute in Sydney, Australia🇦🇺 | former MSCA PhD fellow | interested in genome stability and mechanisms of cell death following DNA replication stress and radiotherapy.
Reposted by Melanie Walter
Please repost - Multiple PhDs available
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
November 5, 2025 at 9:18 AM
Please repost - Multiple PhDs available
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
It was a pleasure to take a step back from maternity leave to present my work at the #acdtm25 in Melbourne this year.
The Cesare Lab had an excellent time at the Australian Cell Cycle, DNA Repair & Telomere Meeting in Melbourne.
australiancellcycle.org
A huge thank you to @genomestability.bsky.social and all the organisers for putting together such a fantastic and inspiring meeting.
We're looking forward to 2027!
australiancellcycle.org
A huge thank you to @genomestability.bsky.social and all the organisers for putting together such a fantastic and inspiring meeting.
We're looking forward to 2027!
October 23, 2025 at 4:27 AM
It was a pleasure to take a step back from maternity leave to present my work at the #acdtm25 in Melbourne this year.
Congratulations @ssegurabayona.bsky.social and team!
Very honoured to have contributed to such an amazing and important paper.
Very honoured to have contributed to such an amazing and important paper.
🚀 New preprint alert!
We uncover SLFN11 as a molecular gatekeeper that restricts alternative lengthening of telomeres (ALT) by sensing telomere-associated replication stress and triggering apoptosis.
📄 Read the manuscript here: www.biorxiv.org/content/10.1...
We uncover SLFN11 as a molecular gatekeeper that restricts alternative lengthening of telomeres (ALT) by sensing telomere-associated replication stress and triggering apoptosis.
📄 Read the manuscript here: www.biorxiv.org/content/10.1...
SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres
The tRNA nuclease SLFN11 is epigenetically silenced in ~50% of treatment-naive tumours and is the strongest predictor of chemoresistance but why it is frequently inactivated in cancer is unknown. To a...
www.biorxiv.org
September 11, 2025 at 7:39 AM
Congratulations @ssegurabayona.bsky.social and team!
Very honoured to have contributed to such an amazing and important paper.
Very honoured to have contributed to such an amazing and important paper.
Reposted by Melanie Walter
We are excited to announce a groundbreaking study out in @natcomms.nature.com from #CMRI Dr Alex Sobinoff & team. They have discovered proteins that guide telomerase — opening doors to new treatments for #cancer, aging & genetic disease. Read more: www.cmrijeansforgenes.org.au/news/scienti...
July 2, 2025 at 3:44 AM
We are excited to announce a groundbreaking study out in @natcomms.nature.com from #CMRI Dr Alex Sobinoff & team. They have discovered proteins that guide telomerase — opening doors to new treatments for #cancer, aging & genetic disease. Read more: www.cmrijeansforgenes.org.au/news/scienti...
Check out the newest review by my talented colleague and friend @scientistkate.bsky.social.
Excited to see our review on the 3D genome in the cell cycle, DNA repair and DNA replication out today!
#3Dgenome #replication #DNArepair #cellcycle #epigenetics #chromatinstructure #chromatinbiology
www.frontiersin.org/journals/cel...
#3Dgenome #replication #DNArepair #cellcycle #epigenetics #chromatinstructure #chromatinbiology
www.frontiersin.org/journals/cel...
March 5, 2025 at 7:57 AM
Check out the newest review by my talented colleague and friend @scientistkate.bsky.social.
For all the genome instability, DDR, cell death and radiation enthusiasts - our new paper is finally out. Congratulations to @szmyd-radoslaw.bsky.social! Feeling honoured to have contributed to this amazing piece of work.
1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....
Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage - Nature Cell Biology
Szmyd et al. show that DNA repair pathways impact whether cells with DNA lesions arrest in mitosis. The formation of homologous recombination-driven double Holliday junctions elicits mitotic cell deat...
www.nature.com
January 13, 2025 at 10:19 AM
For all the genome instability, DDR, cell death and radiation enthusiasts - our new paper is finally out. Congratulations to @szmyd-radoslaw.bsky.social! Feeling honoured to have contributed to this amazing piece of work.