Charles Herndon
@drcyclopath.bsky.social
My education site http://pathologynotebook.com
Incoming PGY1 @UCSFPath
All views are my own
#CytoPath #PediPath #BSTPath #PathSky #Pathology
Incoming PGY1 @UCSFPath
All views are my own
#CytoPath #PediPath #BSTPath #PathSky #Pathology
#1 of 2: Pap from a 30-year-old female.
What is your interpretation?
A) NILM
B) HSIL
C) AIS
#CytoPath #Pathology
#PathSky #PathTwitter
What is your interpretation?
A) NILM
B) HSIL
C) AIS
#CytoPath #Pathology
#PathSky #PathTwitter
August 9, 2025 at 3:43 PM
#1 of 2: Pap from a 30-year-old female.
What is your interpretation?
A) NILM
B) HSIL
C) AIS
#CytoPath #Pathology
#PathSky #PathTwitter
What is your interpretation?
A) NILM
B) HSIL
C) AIS
#CytoPath #Pathology
#PathSky #PathTwitter
#Thyroid FNA shows abundant colloid but no follicular cells.
Interpretation:
A) Non-Diagnostic
B) Benign
#CytoPath #PathTwitter #Pathology #PathSky
Interpretation:
A) Non-Diagnostic
B) Benign
#CytoPath #PathTwitter #Pathology #PathSky
August 8, 2025 at 1:37 PM
#Thyroid FNA shows abundant colloid but no follicular cells.
Interpretation:
A) Non-Diagnostic
B) Benign
#CytoPath #PathTwitter #Pathology #PathSky
Interpretation:
A) Non-Diagnostic
B) Benign
#CytoPath #PathTwitter #Pathology #PathSky
#PapSmear
How would you interpret these glandular cells?
A) Metaplastic
B) Neoplastic
#CytoPath #PathSky #PathTwitter #Pathology#PapSmear
How would you interpret these glandular cells?
A) Metaplastic
B) Neoplastic
#CytoPath #PathSky #PathTwitter #Pathology#PapSmear
August 7, 2025 at 2:07 PM
#PapSmear
How would you interpret these glandular cells?
A) Metaplastic
B) Neoplastic
#CytoPath #PathSky #PathTwitter #Pathology#PapSmear
How would you interpret these glandular cells?
A) Metaplastic
B) Neoplastic
#CytoPath #PathSky #PathTwitter #Pathology#PapSmear
Postmenopausal bleeding in a 65-year-old woman.
Her pap smear is shown. What is your interpretation?
A) Negative for malignancy
B) High grade
C) Squamous cell carcinoma
#CytoPath #Pathology #PathSky
Her pap smear is shown. What is your interpretation?
A) Negative for malignancy
B) High grade
C) Squamous cell carcinoma
#CytoPath #Pathology #PathSky
August 6, 2025 at 3:17 PM
Postmenopausal bleeding in a 65-year-old woman.
Her pap smear is shown. What is your interpretation?
A) Negative for malignancy
B) High grade
C) Squamous cell carcinoma
#CytoPath #Pathology #PathSky
Her pap smear is shown. What is your interpretation?
A) Negative for malignancy
B) High grade
C) Squamous cell carcinoma
#CytoPath #Pathology #PathSky
AUS featuring __ atypia
A) architectural
B) nuclear
#Thyroid #CytoPath #Pathology #PathTwitter #PathSky
A) architectural
B) nuclear
#Thyroid #CytoPath #Pathology #PathTwitter #PathSky
August 5, 2025 at 1:43 PM
AUS featuring __ atypia
A) architectural
B) nuclear
#Thyroid #CytoPath #Pathology #PathTwitter #PathSky
A) architectural
B) nuclear
#Thyroid #CytoPath #Pathology #PathTwitter #PathSky
August 4, 2025 at 1:56 PM
30-year-old female with a diffusely enlarged thyroid.
What is your interpretation of the FNA?🧐
A) Non-Diagnostic
B) Benign
C) Follicular neoplasm
D) Atypia of undetermined significance (AUS)
#CytoPath #PathTwitter #Pathology
What is your interpretation of the FNA?🧐
A) Non-Diagnostic
B) Benign
C) Follicular neoplasm
D) Atypia of undetermined significance (AUS)
#CytoPath #PathTwitter #Pathology
August 3, 2025 at 4:25 PM
30-year-old female with a diffusely enlarged thyroid.
What is your interpretation of the FNA?🧐
A) Non-Diagnostic
B) Benign
C) Follicular neoplasm
D) Atypia of undetermined significance (AUS)
#CytoPath #PathTwitter #Pathology
What is your interpretation of the FNA?🧐
A) Non-Diagnostic
B) Benign
C) Follicular neoplasm
D) Atypia of undetermined significance (AUS)
#CytoPath #PathTwitter #Pathology
Renal pelvis washing reveals a papillary structure.
What is your interpretation? 🧐
A) High grade urothelial carcinoma (HGUC)
B) Atypical urothelial cells
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #PathTwitter #Pathology #GUPath
What is your interpretation? 🧐
A) High grade urothelial carcinoma (HGUC)
B) Atypical urothelial cells
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #PathTwitter #Pathology #GUPath
August 2, 2025 at 10:23 PM
Renal pelvis washing reveals a papillary structure.
What is your interpretation? 🧐
A) High grade urothelial carcinoma (HGUC)
B) Atypical urothelial cells
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #PathTwitter #Pathology #GUPath
What is your interpretation? 🧐
A) High grade urothelial carcinoma (HGUC)
B) Atypical urothelial cells
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #PathTwitter #Pathology #GUPath
MRI core needle biopsy for a non-mass enhancing lesion.
What is your interpretation?
A) Fibrocystic change
B) Intraductal papilloma
C) Apocrine adenosis
#BreastPath #PathSky #Pathology #PathTwitter
🔬 dpa-dapa.com/public/displ...
What is your interpretation?
A) Fibrocystic change
B) Intraductal papilloma
C) Apocrine adenosis
#BreastPath #PathSky #Pathology #PathTwitter
🔬 dpa-dapa.com/public/displ...
May 10, 2025 at 12:46 PM
MRI core needle biopsy for a non-mass enhancing lesion.
What is your interpretation?
A) Fibrocystic change
B) Intraductal papilloma
C) Apocrine adenosis
#BreastPath #PathSky #Pathology #PathTwitter
🔬 dpa-dapa.com/public/displ...
What is your interpretation?
A) Fibrocystic change
B) Intraductal papilloma
C) Apocrine adenosis
#BreastPath #PathSky #Pathology #PathTwitter
🔬 dpa-dapa.com/public/displ...
How will we change #ChangeMedEd??
Where "we" includes you, me, and AI!
Submit your ideas for a $20K grant from the AMA
Deadline: June 13, 2025
www.cvent.com/c/abstracts/...
#MedEd #Pathology #PathTwitter #PathSky
Where "we" includes you, me, and AI!
Submit your ideas for a $20K grant from the AMA
Deadline: June 13, 2025
www.cvent.com/c/abstracts/...
#MedEd #Pathology #PathTwitter #PathSky
May 9, 2025 at 5:11 PM
How will we change #ChangeMedEd??
Where "we" includes you, me, and AI!
Submit your ideas for a $20K grant from the AMA
Deadline: June 13, 2025
www.cvent.com/c/abstracts/...
#MedEd #Pathology #PathTwitter #PathSky
Where "we" includes you, me, and AI!
Submit your ideas for a $20K grant from the AMA
Deadline: June 13, 2025
www.cvent.com/c/abstracts/...
#MedEd #Pathology #PathTwitter #PathSky
Tonsilar lesion. Is it #TooFarToDiagnose?
🧐🧐
A) Squamous cell carcinoma
B) Adenocarcinoma
C) Both
D) Neither
#ENTPath #HeadNeckPath #PathSky
rosai.secondslide.com/view/sem1142...
🧐🧐
A) Squamous cell carcinoma
B) Adenocarcinoma
C) Both
D) Neither
#ENTPath #HeadNeckPath #PathSky
rosai.secondslide.com/view/sem1142...
May 9, 2025 at 4:41 PM
Tonsilar lesion. Is it #TooFarToDiagnose?
🧐🧐
A) Squamous cell carcinoma
B) Adenocarcinoma
C) Both
D) Neither
#ENTPath #HeadNeckPath #PathSky
rosai.secondslide.com/view/sem1142...
🧐🧐
A) Squamous cell carcinoma
B) Adenocarcinoma
C) Both
D) Neither
#ENTPath #HeadNeckPath #PathSky
rosai.secondslide.com/view/sem1142...
Laryngeal biopsy. What would you call this squamous cell proliferation?
🤔
A) hyperplasia
B) dysplasia
C) carcinoma
#OralPath #HeadNeckPath #DermPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
🤔
A) hyperplasia
B) dysplasia
C) carcinoma
#OralPath #HeadNeckPath #DermPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
May 6, 2025 at 12:17 PM
Laryngeal biopsy. What would you call this squamous cell proliferation?
🤔
A) hyperplasia
B) dysplasia
C) carcinoma
#OralPath #HeadNeckPath #DermPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
🤔
A) hyperplasia
B) dysplasia
C) carcinoma
#OralPath #HeadNeckPath #DermPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
Painful palatal ulcer.
What do you think?🧐
A) Benign
B) Malignant
Could it be #TooFarToDiagnose??
#OralPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
What do you think?🧐
A) Benign
B) Malignant
Could it be #TooFarToDiagnose??
#OralPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
May 4, 2025 at 5:20 PM
Painful palatal ulcer.
What do you think?🧐
A) Benign
B) Malignant
Could it be #TooFarToDiagnose??
#OralPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
What do you think?🧐
A) Benign
B) Malignant
Could it be #TooFarToDiagnose??
#OralPath #PathSky #pathology
🔬 tumourclassification.iarc.who.int/Viewer/Index...
Breast core needle biopsy. Diagnosis?
A) Myofibroblastoma
B) Myoid hamartoma
C) Fibrous mastopathy
D) Fibromatosis
#BreastPath #Pathology #PathTwiter #PathSky
🔬 dpa-dapa.com/public/displ...
A) Myofibroblastoma
B) Myoid hamartoma
C) Fibrous mastopathy
D) Fibromatosis
#BreastPath #Pathology #PathTwiter #PathSky
🔬 dpa-dapa.com/public/displ...
May 2, 2025 at 10:08 AM
Breast core needle biopsy. Diagnosis?
A) Myofibroblastoma
B) Myoid hamartoma
C) Fibrous mastopathy
D) Fibromatosis
#BreastPath #Pathology #PathTwiter #PathSky
🔬 dpa-dapa.com/public/displ...
A) Myofibroblastoma
B) Myoid hamartoma
C) Fibrous mastopathy
D) Fibromatosis
#BreastPath #Pathology #PathTwiter #PathSky
🔬 dpa-dapa.com/public/displ...
#1 of 3
Pigmented skin lesion.
Is it #TooFarToDiagnose?
A) Benign nevus
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
Pigmented skin lesion.
Is it #TooFarToDiagnose?
A) Benign nevus
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
May 1, 2025 at 10:46 AM
#1 of 3
Pigmented skin lesion.
Is it #TooFarToDiagnose?
A) Benign nevus
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
Pigmented skin lesion.
Is it #TooFarToDiagnose?
A) Benign nevus
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
FNA of solid pancreatic head mass reveals large epithelioid cells in syncytial groups associated with smaller cells having prominent nucleoli.
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
April 30, 2025 at 11:45 AM
FNA of solid pancreatic head mass reveals large epithelioid cells in syncytial groups associated with smaller cells having prominent nucleoli.
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
#PathSky #Pathology #GIPath #CytoPath
Pigmented skin lesion. Diagnosis?
A) Melanoma in situ
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
🔬 www.virtualpathology.leeds.ac.uk/slides/libra...
A) Melanoma in situ
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
🔬 www.virtualpathology.leeds.ac.uk/slides/libra...
April 29, 2025 at 11:43 AM
Pigmented skin lesion. Diagnosis?
A) Melanoma in situ
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
🔬 www.virtualpathology.leeds.ac.uk/slides/libra...
A) Melanoma in situ
B) Dysplastic nevus
#DermPath #Pathology #Dermatology
🔬 www.virtualpathology.leeds.ac.uk/slides/libra...
Breast core needle biopsy.
Is it #TooFarToDiagnosis?
A) Tubular carcinoma
B) Microglandular adenosis
C) Sclerosing adenosis
D) Radial scar
#PathSky #BreastPath #PathTwitter #Pathology
🔬 dpa-dapa.com/public/displ...
Is it #TooFarToDiagnosis?
A) Tubular carcinoma
B) Microglandular adenosis
C) Sclerosing adenosis
D) Radial scar
#PathSky #BreastPath #PathTwitter #Pathology
🔬 dpa-dapa.com/public/displ...
April 28, 2025 at 12:49 PM
Breast core needle biopsy.
Is it #TooFarToDiagnosis?
A) Tubular carcinoma
B) Microglandular adenosis
C) Sclerosing adenosis
D) Radial scar
#PathSky #BreastPath #PathTwitter #Pathology
🔬 dpa-dapa.com/public/displ...
Is it #TooFarToDiagnosis?
A) Tubular carcinoma
B) Microglandular adenosis
C) Sclerosing adenosis
D) Radial scar
#PathSky #BreastPath #PathTwitter #Pathology
🔬 dpa-dapa.com/public/displ...
FNA of solid pancreatic head mass shows dispersed plasmacytoid cells.
What do you think these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
What do you think these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
April 27, 2025 at 2:38 PM
FNA of solid pancreatic head mass shows dispersed plasmacytoid cells.
What do you think these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
What do you think these cells represent?
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
🔬 learn.mghpathology.org/index.php/WS...
🧐🧐 Is it #TooCloseToDiagnose?
How would you interpret this core needle biopsy?
A) Flat epithelial atypia
B) Atypical ductal hyperplasia
C) Columnar cell change
🔬 pathpresenter.net/public/displ...
#BreastPath #PathSky #PathTwitter #Pathology
How would you interpret this core needle biopsy?
A) Flat epithelial atypia
B) Atypical ductal hyperplasia
C) Columnar cell change
🔬 pathpresenter.net/public/displ...
#BreastPath #PathSky #PathTwitter #Pathology
April 26, 2025 at 3:38 PM
🧐🧐 Is it #TooCloseToDiagnose?
How would you interpret this core needle biopsy?
A) Flat epithelial atypia
B) Atypical ductal hyperplasia
C) Columnar cell change
🔬 pathpresenter.net/public/displ...
#BreastPath #PathSky #PathTwitter #Pathology
How would you interpret this core needle biopsy?
A) Flat epithelial atypia
B) Atypical ductal hyperplasia
C) Columnar cell change
🔬 pathpresenter.net/public/displ...
#BreastPath #PathSky #PathTwitter #Pathology
What would you call these cells from a pap smear?
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology #PathTwitter #PathSky
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology #PathTwitter #PathSky
April 25, 2025 at 12:36 PM
What would you call these cells from a pap smear?
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology #PathTwitter #PathSky
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology #PathTwitter #PathSky
Screening pap smear.
What would you call these cells?
🤔
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology
What would you call these cells?
🤔
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology
April 24, 2025 at 11:50 AM
Screening pap smear.
What would you call these cells?
🤔
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology
What would you call these cells?
🤔
A) High grade squamous lesion (HSIL)
B) Atypical glandular cells (AGC)
C) Benign endometrial cells
D) Tubal metaplasia
#CytoPath #Pathology
Bladder washing.
🧐🧐🧐
What is your interpretation of these spindle cells amid an inflamed stroma?
A) High grade urothelial carcinoma (HGUC)
B) Low-grade urothelial neoplasm (LGUN)
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #GUPath #Pathology #PathSky
🧐🧐🧐
What is your interpretation of these spindle cells amid an inflamed stroma?
A) High grade urothelial carcinoma (HGUC)
B) Low-grade urothelial neoplasm (LGUN)
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #GUPath #Pathology #PathSky
April 21, 2025 at 11:33 AM
Bladder washing.
🧐🧐🧐
What is your interpretation of these spindle cells amid an inflamed stroma?
A) High grade urothelial carcinoma (HGUC)
B) Low-grade urothelial neoplasm (LGUN)
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #GUPath #Pathology #PathSky
🧐🧐🧐
What is your interpretation of these spindle cells amid an inflamed stroma?
A) High grade urothelial carcinoma (HGUC)
B) Low-grade urothelial neoplasm (LGUN)
C) Negative for HGUC
D) Non-urothelial malignancy
#CytoPath #GUPath #Pathology #PathSky
FNA of solid pancreatic head mass.
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
April 20, 2025 at 1:34 PM
FNA of solid pancreatic head mass.
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
What do these cells represent?🧐🧐
A) Acinar cell carcinoma
B) Neuroendocrine tumor
C) Pancreatoblastoma
D) Solid pseudopapillary neoplasm
#PathSky #Pathology #GIPath #CytoPath
Fungus among us 🍄?!
Or bacteria in the area 🦠?!
What do you see on this a Grocott methenamine silver (GMS) stain?
#Pathology #PathTwitter
Or bacteria in the area 🦠?!
What do you see on this a Grocott methenamine silver (GMS) stain?
#Pathology #PathTwitter
April 19, 2025 at 12:15 PM
Fungus among us 🍄?!
Or bacteria in the area 🦠?!
What do you see on this a Grocott methenamine silver (GMS) stain?
#Pathology #PathTwitter
Or bacteria in the area 🦠?!
What do you see on this a Grocott methenamine silver (GMS) stain?
#Pathology #PathTwitter