Chelsey Derderian-LeBlang, PhD
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dr-cjdl.bsky.social
Chelsey Derderian-LeBlang, PhD
@dr-cjdl.bsky.social
Postdoc neuroscientist studying molecular mechanisms of degeneration in the CNS and PNS. Passion for all glia, creating iPSC models, and fluorescent imaging 🧫🔬🧠

https://chelseyjleblang.owlstown.net
Pinned
Intro post 👋🏻

Current postdoc in the Segal Lab at DFCI/ HMS using iPSC models to study axonal degeneration in the CNS and PNS👩🏼‍🔬

Interests include
⚡️pain and neuropathy
🔥neuroinflammation
🧠ADRD
💧biomolecular condensates
🔬 high resolution imaging
🐈‍⬛ cats
Reposted by Chelsey Derderian-LeBlang, PhD
“It’s extremely alarming that grants that have been vetted by the scientific community and deemed important and impactful to understand the world are now being cancelled because of political ideology,” says @lkfazio.bsky.social.

“This is direct censorship of scientific research.”
Exclusive: NIH to terminate hundreds of active research grants
Studies that touch on LGBT+ health, gender identity and DEI in the biomedical workforce could be terminated, according to documents obtained by Nature.
www.nature.com
March 6, 2025 at 2:17 AM
Reposted by Chelsey Derderian-LeBlang, PhD
They didn’t wait until Monday, nice! More of this! Including in defense of our trainees!
February 8, 2025 at 8:32 PM
Reposted by Chelsey Derderian-LeBlang, PhD
HOW COOL IS THIS?! Scientists have discovered a new way to destroy cancer cells. By stimulating aminocyanine molecules with near-infrared light, cancer cells vibrate in sync, enough to break apart their membranes! These “molecular jackhammers” DESTROYED 99% of cancer cells! 🧪🧵⬇️
December 27, 2024 at 5:00 PM
Reposted by Chelsey Derderian-LeBlang, PhD
Lots of exciting stuff in the #painresearch field yesterday. 4 papers and 1 news piece, but let's start with a...
BOOM! www.science.org/doi/10.1126/... big breakthrough on CIPN from Cheryl Stucky's lab led by @amikesell.bsky.social with @katesadlerphd.bsky.social
Increased keratinocyte activity and PIEZO1 signaling contribute to paclitaxel-induced mechanical hypersensitivity
Sensitization of the keratinocyte mechanotransducer PIEZO1 contributes to paclitaxel-induced touch pain.
www.science.org
December 13, 2024 at 7:16 PM
Reposted by Chelsey Derderian-LeBlang, PhD
@aliibarry.bsky.social ‘s excellent work on human DRG proteomics is now online. Collaboration between our lab and Manuela Schmidt’s lab in Austria. Ali’s multiomic integration analysis leads to some unique new insight into pain mechanisms with strong proteomic support.
Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway https://www.biorxiv.org/content/10.1101/2024.12.06.626968v1
December 10, 2024 at 11:43 AM
Reposted by Chelsey Derderian-LeBlang, PhD
A complement to @peiferlabunc.bsky.social reposting this image – it was the cover of the 40th anniversary issue of J Neuroscience back in 2021, together with an historical review on imaging the neuronal cytoskeleton with lots of cool pictures: www.jneurosci.org/content/41/1...
November 25, 2024 at 4:25 PM
First #FluorescenceFriday: two cute #iPSC derived pseudounipolar #sensory #neurons. Still in awe every time I generate these cells. For more information about this protocol see my pre-print on biorxiv, and stay tuned for a revised manuscript soon!
www.biorxiv.org/content/10.1...
November 22, 2024 at 2:59 PM
Reposted by Chelsey Derderian-LeBlang, PhD
🚨 Update for #RNA science fans:
I checked on #Bsky registry, and here is a 'condensate' (😆) of all #RNA #RNAsky starter packs so far:
1. General RNA biology #1
go.bsky.app/RN6HnZp
November 21, 2024 at 8:08 AM
Reposted by Chelsey Derderian-LeBlang, PhD
Cool new paper from Camilla Svensson’s team and a reminder to not give up understanding NGF signsling for pain treatment! journals.lww.com/pain/fulltex...
Sex-dependent effects of the targeted nerve growth factor... : PAIN
inflammation-induced pain-related behaviors and bone loss. The hNGF-R100E mutation did not alter the nerve fiber density in the sciatic nerve, ankle joint synovium, and skin of naïve mice. Withdrawal ...
journals.lww.com
November 19, 2024 at 11:31 AM
Reposted by Chelsey Derderian-LeBlang, PhD
By popular demand: the Axon Degeneration starter pack. Definitely incomplete so let me know who I missed.

go.bsky.app/5BH6mBE
Axon degeneration
Join the conversation
go.bsky.app
November 19, 2024 at 7:36 AM
Reposted by Chelsey Derderian-LeBlang, PhD
I started (at @katesadlerphd.bsky.social's suggestion, thanks Kate for pushing me) a pain neuroscience and pain research starter pack. I am sure I have missed many people so if I missed you, I am sorry, but please just ask me to add you in the thread below and I will do that. go.bsky.app/KboKNhg
November 18, 2024 at 4:58 PM
🧡🤍🩷
There are lots of things I love about being #QueerInSTEM, but the best thing by far is our community. Happy International Day of LGBTQIA+ People in STEM.
November 18, 2024 at 3:31 PM
Reposted by Chelsey Derderian-LeBlang, PhD
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?

go.bsky.app/MHtJzeC
November 17, 2024 at 8:35 PM
Reposted by Chelsey Derderian-LeBlang, PhD
Microglia community, let’s start the discussion 🧠 follow the Microglia Starter Pack and ask @mancusorenzo.bsky.social to add your colleagues as they join Bluesky 🦋

go.bsky.app/DT3Cp4A
November 17, 2024 at 12:52 PM
Reposted by Chelsey Derderian-LeBlang, PhD
Download our database of 492 (!) funding opportunities for EARLY-CAREER FACULTY AND RESEARCHERS.

For each entry, we provide link to funder, description, amount, deadline, and eligibility criteria (e.g. citizenship).

Download freely here: research.jhu.edu/rdt/funding-...
November 17, 2024 at 4:38 PM
Intro post 👋🏻

Current postdoc in the Segal Lab at DFCI/ HMS using iPSC models to study axonal degeneration in the CNS and PNS👩🏼‍🔬

Interests include
⚡️pain and neuropathy
🔥neuroinflammation
🧠ADRD
💧biomolecular condensates
🔬 high resolution imaging
🐈‍⬛ cats
November 17, 2024 at 5:08 PM
Reposted by Chelsey Derderian-LeBlang, PhD
go.bsky.app/Lyzro3M

!WELCOME!

thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.

apologies for missing many of you - please do reply to get added

and remember to repost so the newbies can find us!
November 14, 2024 at 3:21 AM