Dong Heun Lee(이동흔)
@dongleemd.bsky.social
Infectious disease physician @UCSF_ID, #TxID, 🇰🇷
Reposted by Dong Heun Lee(이동흔)
Did you miss the #IDWeek2025 session on Lassa fever? Check out our recap and more in IDWeek Daily News:
www.pageturnpro.com/JHCLLC/11289...
www.pageturnpro.com/JHCLLC/11289...
October 21, 2025 at 11:05 AM
Did you miss the #IDWeek2025 session on Lassa fever? Check out our recap and more in IDWeek Daily News:
www.pageturnpro.com/JHCLLC/11289...
www.pageturnpro.com/JHCLLC/11289...
Reposted by Dong Heun Lee(이동흔)
Reposted by Dong Heun Lee(이동흔)
One of the most challenging encounters in the outpatient practice of infectious diseases, summarized here wonderfully in @cidjournal.bsky.social by Drs. Advani and colleagues.
Have already used this algorithm several times!
doi.org/10.1093/cid/...
Have already used this algorithm several times!
doi.org/10.1093/cid/...
State-of-the-Art Review: Recurrent Uncomplicated Urinary Tract Infections in Women
Abstract. Over 50% of adult women experience at least 1 urinary tract infection (UTI) in their lifetime, and almost one-quarter of them will experience a r
doi.org
April 29, 2025 at 9:46 AM
One of the most challenging encounters in the outpatient practice of infectious diseases, summarized here wonderfully in @cidjournal.bsky.social by Drs. Advani and colleagues.
Have already used this algorithm several times!
doi.org/10.1093/cid/...
Have already used this algorithm several times!
doi.org/10.1093/cid/...
Reposted by Dong Heun Lee(이동흔)
In CID, Michael R Hodges and colleagues evaluated fosmanogepix (FMGX) treatment in invasive mold diseases (IMDs) by Aspergillus spp. and rare molds in adults with limited treatment options. academic.oup.com/cid/advance-...
Fosmanogepix for the Treatment of Invasive Mold Diseases Caused by Aspergillus Species and Rare Molds: A Phase 2, Open-Label Study (AEGIS)
Fosmanogepix 1000mg IV (loading dose) and 600mg IV or 800mg oral (maintenance dose) was associated with an all-cause mortality of 25% at Day 42 with accept
academic.oup.com
April 15, 2025 at 11:22 PM
In CID, Michael R Hodges and colleagues evaluated fosmanogepix (FMGX) treatment in invasive mold diseases (IMDs) by Aspergillus spp. and rare molds in adults with limited treatment options. academic.oup.com/cid/advance-...
Reposted by Dong Heun Lee(이동흔)
STOMP Study Interim analysis:
- TPOXX (tecovirimat) showed no improvement in lesion resolution time vs placebo in adults with mild-to-moderate clade II mpox
- Enrollment stopped in all study arms
- Strong safety profile
- Efficacy in severe cases not assessed
www.globenewswire.com/news-release...
- TPOXX (tecovirimat) showed no improvement in lesion resolution time vs placebo in adults with mild-to-moderate clade II mpox
- Enrollment stopped in all study arms
- Strong safety profile
- Efficacy in severe cases not assessed
www.globenewswire.com/news-release...
Interim Results from STOMP Study of SIGA’s Tecovirimat in Treatment of Mpox Announced
Interim analysis shows that tecovirimat did not improve time to lesion resolution compared to placebo in adults with mild to moderate clade II mpoxStudy...
www.globenewswire.com
December 10, 2024 at 9:19 PM
STOMP Study Interim analysis:
- TPOXX (tecovirimat) showed no improvement in lesion resolution time vs placebo in adults with mild-to-moderate clade II mpox
- Enrollment stopped in all study arms
- Strong safety profile
- Efficacy in severe cases not assessed
www.globenewswire.com/news-release...
- TPOXX (tecovirimat) showed no improvement in lesion resolution time vs placebo in adults with mild-to-moderate clade II mpox
- Enrollment stopped in all study arms
- Strong safety profile
- Efficacy in severe cases not assessed
www.globenewswire.com/news-release...
Reposted by Dong Heun Lee(이동흔)
So excited to have the Donor-Derived Infection Special Edition out - thanks to Stephanie Pouch and Karen Waller for being guest editors for this special edition!
onlinelibrary.wiley.com/toc/13993062...
onlinelibrary.wiley.com/toc/13993062...
Donor‐Derived Infections: Transplant Infectious Disease: Vol 26, No S1
Click on the title to browse this issue
onlinelibrary.wiley.com
December 4, 2024 at 10:21 PM
So excited to have the Donor-Derived Infection Special Edition out - thanks to Stephanie Pouch and Karen Waller for being guest editors for this special edition!
onlinelibrary.wiley.com/toc/13993062...
onlinelibrary.wiley.com/toc/13993062...
Reposted by Dong Heun Lee(이동흔)
We are so excited to welcome our new class of ID Fellows for next year – what an amazing group!!
December 4, 2024 at 6:01 PM
We are so excited to welcome our new class of ID Fellows for next year – what an amazing group!!
Reposted by Dong Heun Lee(이동흔)
The results of the SOT subgroup analysis of the SOLTICE Phase III RCT (Maribavir vs. IAT) are consistent with those of the overall population. > Effectiveness < Discontinuations. #TxID #IDSky #ViroSky #MedSky pubmed.ncbi.nlm.nih.gov/39613120/
Maribavir for refractory cytomegalovirus infection (with or without resistance) in solid organ transplant recipients: subgroup analysis of the phase 3 randomized SOLSTICE study - PubMed
ClinicalTrials.gov; NCT02931539 DATA AVAILABILITY STATEMENT: The datasets, including the redacted study protocol, redacted statistical analysis plan, and individual participants data supporting the re...
pubmed.ncbi.nlm.nih.gov
November 30, 2024 at 11:35 PM
The results of the SOT subgroup analysis of the SOLTICE Phase III RCT (Maribavir vs. IAT) are consistent with those of the overall population. > Effectiveness < Discontinuations. #TxID #IDSky #ViroSky #MedSky pubmed.ncbi.nlm.nih.gov/39613120/
Reposted by Dong Heun Lee(이동흔)
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Virtual Home Care for Patients With Acute Illness
This cohort study compares outcomes of patients receiving care in an outpatient, virtual, home-based acute care model with outcomes of patients receiving standard hospital care.
jamanetwork.com
November 30, 2024 at 9:24 PM
For my inaugural post, Im proud to announce the publication of our Safer@Home care model. This is going to change how medicine is practiced. No need to admit pts "for IV antibiotics" anymore. Or just for IV diuresis in CHF. Or just for EtOH withdrawal. Etc.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Dong Heun Lee(이동흔)
On World AIDS Day, let's remember those we've lost, support those living with HIV, and continue the fight for awareness and treatment. ❤️ #WorldAIDSDay2024 #IDSky #HIVSky @idsainfo.bsky.social @hivma.bsky.social
December 1, 2024 at 12:41 PM
On World AIDS Day, let's remember those we've lost, support those living with HIV, and continue the fight for awareness and treatment. ❤️ #WorldAIDSDay2024 #IDSky #HIVSky @idsainfo.bsky.social @hivma.bsky.social
Reposted by Dong Heun Lee(이동흔)
Just a friendly reminder that, in light of the IV fluid shortage, switching to PO antibiotics can be a safe, effective, and patient-centered option! This is because bacteria don't care how the antibiotic gets in.
Take, for example, Gram-negative rod bacteremia!
Take, for example, Gram-negative rod bacteremia!
November 30, 2024 at 4:31 PM
Just a friendly reminder that, in light of the IV fluid shortage, switching to PO antibiotics can be a safe, effective, and patient-centered option! This is because bacteria don't care how the antibiotic gets in.
Take, for example, Gram-negative rod bacteremia!
Take, for example, Gram-negative rod bacteremia!
Reposted by Dong Heun Lee(이동흔)
Latest State-of-the-Art Review in @cidjournal.bsky.social comes from Dr. Miriam Barshak et al on ocular infections.
(I had the pleasure of precepting Miriam in clinic around 20+ years ago --but who's counting! -- and she is brilliant and awesome.) @nottheogdrv.bsky.social
doi.org/10.1093/cid/...
(I had the pleasure of precepting Miriam in clinic around 20+ years ago --but who's counting! -- and she is brilliant and awesome.) @nottheogdrv.bsky.social
doi.org/10.1093/cid/...
State-of-the-Art Review: Ocular Infections
Collaborations between ophthalmologists and infectious disease specialists are critical for optimizing care of many patients with eye infections. We review
doi.org
November 22, 2024 at 10:30 AM
Latest State-of-the-Art Review in @cidjournal.bsky.social comes from Dr. Miriam Barshak et al on ocular infections.
(I had the pleasure of precepting Miriam in clinic around 20+ years ago --but who's counting! -- and she is brilliant and awesome.) @nottheogdrv.bsky.social
doi.org/10.1093/cid/...
(I had the pleasure of precepting Miriam in clinic around 20+ years ago --but who's counting! -- and she is brilliant and awesome.) @nottheogdrv.bsky.social
doi.org/10.1093/cid/...
Reposted by Dong Heun Lee(이동흔)
Interesting cluster report of symptomatic individuals in NYC presumed from Entamoeba disbar, likely sexually transmitted.
academic.oup.com/ofid/advance...
academic.oup.com/ofid/advance...
Symptomatic Entamoeba dispar Infections Among Men Who Have Sex With Men, New York City, 2018
Abstract. Entamoeba histolytica is considered the primary species causing the parasitic gastrointestinal infection amebiasis. A cluster of amebiasis infect
academic.oup.com
November 26, 2024 at 12:44 AM
Interesting cluster report of symptomatic individuals in NYC presumed from Entamoeba disbar, likely sexually transmitted.
academic.oup.com/ofid/advance...
academic.oup.com/ofid/advance...
Reposted by Dong Heun Lee(이동흔)
Excellent thread by @dralicehan.bsky.social on this important paper in @cidjournal.bsky.social.
Dramatic increase in cure with telehealth vs referral to local providers.
Very concerning that telehealth coverage might soon be limited -- it's one of the silver linings of the pandemic.
#IDSky
Dramatic increase in cure with telehealth vs referral to local providers.
Very concerning that telehealth coverage might soon be limited -- it's one of the silver linings of the pandemic.
#IDSky
#IDsky 🧵
We know telehealth is incredible at expanding access
This study randomized PWUD & hep C viremia in rural Oregon to telehealth vs referral to local providers
doi.org/10.1093/cid/...
We know telehealth is incredible at expanding access
This study randomized PWUD & hep C viremia in rural Oregon to telehealth vs referral to local providers
doi.org/10.1093/cid/...
November 27, 2024 at 10:33 PM
Excellent thread by @dralicehan.bsky.social on this important paper in @cidjournal.bsky.social.
Dramatic increase in cure with telehealth vs referral to local providers.
Very concerning that telehealth coverage might soon be limited -- it's one of the silver linings of the pandemic.
#IDSky
Dramatic increase in cure with telehealth vs referral to local providers.
Very concerning that telehealth coverage might soon be limited -- it's one of the silver linings of the pandemic.
#IDSky
Reposted by Dong Heun Lee(이동흔)
Reposted by Dong Heun Lee(이동흔)
In this single-center retrospective study, @mularoni.bsky.social tested donors (3%) and recipients (8%) for HHV-8. Most of the donor-derived HHV-8-related disease manifested as KICS!! 🤯 On the other hand, most reactivations presented as KS. #TxID #IDSky pubmed.ncbi.nlm.nih.gov/39551265/
Serologic screening and molecular surveillance of Kaposi sarcoma herpesvirus (KSHV)/human herpesvirus-8 (HHV-8) infections for early recognition and effective treatment of KSHV-associated inflammatory...
Kaposi sarcoma herpesvirus/human herpesvirus-8 (HHV-8) neoplastic and non-neoplastic disease in solid organ transplant (SOT) recipients can be life-threatening. We evaluated the seroprevalence of HHV-...
pubmed.ncbi.nlm.nih.gov
November 29, 2024 at 3:48 PM
In this single-center retrospective study, @mularoni.bsky.social tested donors (3%) and recipients (8%) for HHV-8. Most of the donor-derived HHV-8-related disease manifested as KICS!! 🤯 On the other hand, most reactivations presented as KS. #TxID #IDSky pubmed.ncbi.nlm.nih.gov/39551265/
Donor-derived Mycoplasma and Ureaplasma infections in Lung Transplant: 18% of donors tested positive. Culture had higher positive predictive value (PPV) compared to PCR.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 29, 2024 at 6:43 PM
Donor-derived Mycoplasma and Ureaplasma infections in Lung Transplant: 18% of donors tested positive. Culture had higher positive predictive value (PPV) compared to PCR.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Dong Heun Lee(이동흔)
🌟"Today’s teaching point may end up as tomorrow’s myth." 🌟
Dr.Erin McCreary article 👇
#idquotes #idsky #medsky #AMSsky
academic.oup.com/cid/article/...
Dr.Erin McCreary article 👇
#idquotes #idsky #medsky #AMSsky
academic.oup.com/cid/article/...
November 29, 2024 at 9:06 AM
🌟"Today’s teaching point may end up as tomorrow’s myth." 🌟
Dr.Erin McCreary article 👇
#idquotes #idsky #medsky #AMSsky
academic.oup.com/cid/article/...
Dr.Erin McCreary article 👇
#idquotes #idsky #medsky #AMSsky
academic.oup.com/cid/article/...
Reposted by Dong Heun Lee(이동흔)
We will have another pandemic. The question is not if but when. Excellent viewpoint in CID from 2 veterans of #publichealth Anthony Fauci & Greg Folkers. Speakly plainly they hold no punches reflecting on HIV & COVID. We need their wisdom esp now.
A must read! #IDSky
academic.oup.com/cid/advance-...
A must read! #IDSky
academic.oup.com/cid/advance-...
HIV/AIDS and COVID-19: Shared Lessons from Two Pandemics
The HIV/AIDS and COVID-19 pandemics hold important lessons for preparing for, and responding to, future infectious disease outbreaks. Eight lessons common
academic.oup.com
November 28, 2024 at 4:56 PM
We will have another pandemic. The question is not if but when. Excellent viewpoint in CID from 2 veterans of #publichealth Anthony Fauci & Greg Folkers. Speakly plainly they hold no punches reflecting on HIV & COVID. We need their wisdom esp now.
A must read! #IDSky
academic.oup.com/cid/advance-...
A must read! #IDSky
academic.oup.com/cid/advance-...
Reposted by Dong Heun Lee(이동흔)
Don't you just love a good disease primer. Especially for neglected rare diseases we don't see in clinical practice on the daily. This #leprosy primer in nature reviews is great and comes with a snapshot summary that's very digestible.
#IDSky #MedSky
www.nature.com/articles/s41....
#IDSky #MedSky
www.nature.com/articles/s41....
November 28, 2024 at 2:19 PM
Don't you just love a good disease primer. Especially for neglected rare diseases we don't see in clinical practice on the daily. This #leprosy primer in nature reviews is great and comes with a snapshot summary that's very digestible.
#IDSky #MedSky
www.nature.com/articles/s41....
#IDSky #MedSky
www.nature.com/articles/s41....
Reposted by Dong Heun Lee(이동흔)
A systematic review of 24 randomized trials for #LongCovid
www.bmj.com/content/387/... open-access
No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty).
We're still in desperate need for a validated treatment!
www.bmj.com/content/387/... open-access
No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty).
We're still in desperate need for a validated treatment!
November 27, 2024 at 11:57 PM
A systematic review of 24 randomized trials for #LongCovid
www.bmj.com/content/387/... open-access
No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty).
We're still in desperate need for a validated treatment!
www.bmj.com/content/387/... open-access
No drug, diet, or device intervention has supportive evidence for efficacy. CBT, rehab provided some relief of symptoms (moderate certainty).
We're still in desperate need for a validated treatment!
Reposted by Dong Heun Lee(이동흔)
Inaugural article in a new section in @cidjournal.bsky.social called
“Clinical Dilemmas in Infectious Diseases”
led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning
Rewriting the Script
academic.oup.com/cid/advance-... #IDSky
“Clinical Dilemmas in Infectious Diseases”
led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning
Rewriting the Script
academic.oup.com/cid/advance-... #IDSky
Rewriting the Script
Natasha Spottiswoode, MD DPhil, Daniel J Minter, MD, Rachel Friedman-Moraco, MD; Rewriting the Script, Clinical Infectious Diseases, , ciae589, https://doi
academic.oup.com
November 27, 2024 at 2:00 PM
Inaugural article in a new section in @cidjournal.bsky.social called
“Clinical Dilemmas in Infectious Diseases”
led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning
Rewriting the Script
academic.oup.com/cid/advance-... #IDSky
“Clinical Dilemmas in Infectious Diseases”
led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning
Rewriting the Script
academic.oup.com/cid/advance-... #IDSky
Reposted by Dong Heun Lee(이동흔)
Tenets of Infectious Diseases:
1. Source control, source control, source control
2. Stuff sticks to metal (and other material)
3. The drug has to get in to work (GI absorption, tissue penetration, presence of walled-off collection, etc.)
4. Antibiotics should not be anxiolytics
1. Source control, source control, source control
2. Stuff sticks to metal (and other material)
3. The drug has to get in to work (GI absorption, tissue penetration, presence of walled-off collection, etc.)
4. Antibiotics should not be anxiolytics
November 27, 2024 at 9:29 PM
Tenets of Infectious Diseases:
1. Source control, source control, source control
2. Stuff sticks to metal (and other material)
3. The drug has to get in to work (GI absorption, tissue penetration, presence of walled-off collection, etc.)
4. Antibiotics should not be anxiolytics
1. Source control, source control, source control
2. Stuff sticks to metal (and other material)
3. The drug has to get in to work (GI absorption, tissue penetration, presence of walled-off collection, etc.)
4. Antibiotics should not be anxiolytics
Reposted by Dong Heun Lee(이동흔)
Additionally, the updated research criteria for HOPE Act transplants are out. You have 15 days to share your thoughts on the revised criteria using the instruction in the notice!
www.federalregister.gov/documents/20...
www.federalregister.gov/documents/20...
Draft Revised Human Immunodeficiency Virus (HIV) Organ Policy Equity Act Safeguards and Research Criteria for Transplantation of Organs Infected With HIV
The HOPE Act requires the Secretary of Health and Human Services (the Secretary) to develop and publish criteria for research involving the transplantation of organs from donors with HIV to recipients...
www.federalregister.gov
November 27, 2024 at 1:27 PM
Additionally, the updated research criteria for HOPE Act transplants are out. You have 15 days to share your thoughts on the revised criteria using the instruction in the notice!
www.federalregister.gov/documents/20...
www.federalregister.gov/documents/20...