Djoser Genomics
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djosergenomics.github.io
Djoser Genomics
@djosergenomics.github.io
Exploring #SyntheticBiology & #Bioinformatics + Documenting my learning journey | Built by @noureldenrihan.bsky.social | 🌐 djosergenomics.github.io
Pinned
A major milestone: my first RNAseq preprint is now live on bioRxiv 🎉🎊

I reanalyzed public data from the human SCG to uncover neuroimmune signatures during cardiac disease.🧬🖥️

This was an awesome learning experience and I am excited use everything I learned for new project ideas :D.

#Bioinformatics
Transcriptomic Signatures of Neuroinflammation and Adaptive Immunity in the Human SCG During Cardiac Disease: A Bulk RNA-seq Reanalysis https://www.biorxiv.org/content/10.1101/2025.05.18.654713v1
Part of HTGAA Week 4 is to write a proposal on an In-silico Bacteriophage Engineering.

My proposal: 'ArmoredPhage' 🛡️

My goal: Engineer a Thermostable MS2 Bacteriophage Using Protein Design Techniques.

Check it out:
djosergenomics.github.io/Armored-Phag...

#HTGAA #synbio #AlphaFold #proteindesign
November 11, 2025 at 5:21 PM
Week 4 of HTGAA (Protein Design) is done & I'm amazed!

I was always intimidated by 3D protein models in papers & never thought I'd understand them one day!

Today, I loaded a PDB file into PyMOL, saw the alpha helices & beta sheets of my Tyrosinase enzyme.

This is so cool. 🚀
#HTGAA #proteindesign
November 11, 2025 at 2:27 AM
Week 3 of HTGAA is all about lab automation! 🤖

I wrote a script to program a virtual Opentrons robot to draw my Djoser Genomics pyramid. It simulates robots pipetting 100+ dots of fluorescent E.coli because manually it is slow & error-prone.

#HTGAA #synbio #Opentrons #automation #bioinformatics
October 31, 2025 at 12:34 AM
I am going to audit the How to Grow Almost Anything (HTGAA) course for my first introduction to my Synthetic Biology journey.

I just did the Bio Bootcamp, & i really loved the interactive sessions on Benchling and Opentrons.

Super Excited for more!
#SyntheticBiology #Bioengineering #MIT #HTGAA
October 23, 2025 at 4:27 PM
I decided to take a deep dive into Synthetic Biology, Bio & Genetic Engineering, something I've wanted to learn for a while.

I believe it holds incredible potential & innovation for the future if used correctly

Got any tips or resources? :D
#SyntheticBiology #Bioengineering
October 17, 2025 at 11:26 PM
Introducing Field Notes from the Step Pyramid!

The target is a space where I can document and share my thoughts, experiences, dreams, & struggles as I navigate through bioinformatics & computational biology.

I will also share snippets from it here to be able to engage with others and learn more.
Field Note 00: Dispatch from the Step Pyramid
Hey everyone 👋 So, something new is happening at Djoser Genomics.
djosergenomics.github.io
October 17, 2025 at 12:04 AM
Been busy with final exams in med school for the last couple of weeks, still not done! But I'll have some time to get back here :)

I've got some new projects and ideas that I'm excited about, so stay tuned! :D
October 16, 2025 at 3:35 AM
🥳 Happy 1st Birthday to Djoser Genomics! 🥳

From starting Djoser Genomics, Learning and Exploring Various Projects, to publishing my first preprint and creating the Bulk RNAseq Tutorial Codex!

Thank you for being part of this journey so far. Here’s to Year Two. 🚀

#Bioinformatics #DjoserGenomics
Djoser Genomics: Year One
Today marks Djoser Genomics’ 1st Birthday.
djosergenomics.github.io
September 16, 2025 at 5:38 PM
🎉 The Bulk RNAseq Tutorial Codex is now complete! 🎉

From dataset discovery all the way to enrichment analyses

Every scroll 📜 is now available, covering alignment, quantification, DEGs, visualization & everything in between

The Codex is yours to explore ✨

#RNAseq #Bioinformatics #scicomm
🧬 Introducing the Bulk RNA-seq Tutorial Codex.

A step-by-step series where I guide you through real transcriptomics analysis, one scroll at a time.

Check out the blog post and follow the codex 👉 djosergenomics.github.io/Bulk-RNAseq-...

#Bioinformatics #RNAseq #scicomm
Djoser’s Bulk RNAseq Tutorial Codex
A beginner friendly bulk RNAseq tutorial series told through step by step guides and inspired by ancient Egyptian History.
djosergenomics.github.io
August 20, 2025 at 4:28 PM
Reposted by Djoser Genomics
New Zealand’s prescribing habits likely helped create a homegrown #MRSA 🇳🇿🧬💊

Now ‘AK3’ has been detected overseas

Our recent study shows how it evolved & how #Genomics can help reduce the impact of the next ‘superbug’

#AMR is an issue for everyone
#SciComm

🖥️🧬💻
#AcademicSky
#MicroSky
🧪🧫🦠
Over-subscription of a topical antibiotic likely led to the emergence of a superbug which is now the leading cause of resistant infections.
Antibiotic use likely fuelled the rise of a ‘superbug’ in NZ – genomics offers a defence against the next threat
theconversation.com
August 18, 2025 at 3:01 AM
📜 Scroll VIII: Djoser's Discoveries!

The Grand Finale, we dive into Gene set Enrichment Analysis (GSEA), why we do it, how we do it and how to visualize and interpret it.

Check it out: djosergenomics.github.io/Scroll-8-Djo...

#bioinformatics #RNAseq #scicomm
August 15, 2025 at 10:55 PM
📜 Scroll VII: Thutmose's Trends!

Here, We identify Trends among our DEGs using Functional (GO) and Pathway (KEGG) Enrichment Analysis!

Check it out: djosergenomics.github.io/Scroll-7-Thu...

#bioinformatics #RNAseq #scicomm
August 15, 2025 at 12:58 AM
📜 Scroll VI: Ramses' Plots!

We dive into Visualizations!

MA, PCA, Volcano Plots and Heatmaps!

Check it out: djosergenomics.github.io/Scroll-6-Ram...

#bioinformatics #RNAseq #scicomm
August 14, 2025 at 12:37 AM
📜 Scroll V: Menkaure's Measures!

We dive into Differential expression analysis (DEA), using DESeq2, and how to interpret the findings

Check it out: djosergenomics.github.io/Scroll-5-Men...

#bioinformatics #RNAseq #scicomm
August 12, 2025 at 1:56 AM
Reposted by Djoser Genomics
Q: What can we learn about plants via metabolomics analysis? 🌱🤔
A: Lots of interesting and useful things! Read our blog to find out what they are:
www.fiosgenomics.com/plant-metabo...

#metabolomics #plantmetabolomics #metabolomicsanalysis #bioinformatics
August 11, 2025 at 2:02 PM
📜 Scroll IV: Khafre’s Connections is here!

We step into the next stage of our RNAseq journey!
Importing Kallisto results into R, linking them to gene annotations, & building a strong foundation for downstream analysis

Here: djosergenomics.github.io/Scroll-4-Kha...

#bioinformatics #RNAseq #scicomm
August 9, 2025 at 9:09 PM
🧬 Scroll 3 of the Bulk RNA-seq Tutorial Codex is here!

⚒️ Guided by King Khufu, we pseudoalign our reads using Kallisto — fast, efficient, and accurate.

🌐 Full tutorial + cultural spotlight:

📜 djosergenomics.github.io/Scroll-3-Khu...

#RNAseq #bioinformatics #scicomm
August 7, 2025 at 10:38 PM
🔍 Scroll 2 of Djoser’s Bulk RNAseq Tutorial Codex is here!

We dive into RNA-seq Quality Control with FASTQC — guided by Hesy-Ra, the first known dentist & physician in history.

🧪 Read here: djosergenomics.github.io/Scroll-2-Hes...

#bioinformatics #RNAseq #scicomm
August 5, 2025 at 10:57 PM
Did you know? 🧠

The Original Step Pyramid that inspired our logo was designed by Imhotep — the same ancient figure featured in Scroll 1 of our Bulk RNAseq Tutorial Codex.

Dive in Now ↓

#RNAseq #Bioinformatics #SciComm
🎊 Scroll 1 of Djoser’s Bulk RNAseq Tutorial Codex: Imhotep's Insights 🎊

We start by collecting real RNA-seq data from ENA using Google Colab.

Inspired by Imhotep - ancient Egypt’s architect of the Pyramid of Djoser.

📜 Check it out: djosergenomics.github.io/Scroll-1-Imh...

#bioinformatics #RNAseq
August 5, 2025 at 6:49 PM
🎊 Scroll 1 of Djoser’s Bulk RNAseq Tutorial Codex: Imhotep's Insights 🎊

We start by collecting real RNA-seq data from ENA using Google Colab.

Inspired by Imhotep - ancient Egypt’s architect of the Pyramid of Djoser.

📜 Check it out: djosergenomics.github.io/Scroll-1-Imh...

#bioinformatics #RNAseq
August 5, 2025 at 2:00 AM
🧬 Introducing the Bulk RNA-seq Tutorial Codex.

A step-by-step series where I guide you through real transcriptomics analysis, one scroll at a time.

Check out the blog post and follow the codex 👉 djosergenomics.github.io/Bulk-RNAseq-...

#Bioinformatics #RNAseq #scicomm
Djoser’s Bulk RNAseq Tutorial Codex
A beginner friendly bulk RNAseq tutorial series told through step by step guides and inspired by ancient Egyptian History.
djosergenomics.github.io
August 4, 2025 at 3:31 PM
I'm planning on making a series of mini blog tutorials on bulk RNAseq, they'll be beginner friendly to help someone who's just starting.

I'm also planning to theme it around ancient Egypt just like Djoser ;D

So stay tuned!

#Bioinfomatics #RNAseq
August 2, 2025 at 7:46 PM
Reposted by Djoser Genomics
Only a few days left to apply to join our lab and do exciting senescence research at the University of Cambridge Cancer Research UK Cambridge Institute @cruk-ci.bsky.social @cam.ac.uk 🧪🧬

You can also send informal enquiries (info below):

www.jobs.cam.ac.uk/job/52026/
www.jobs.cam.ac.uk/job/52027/
a cartoon character is surrounded by cats and the caption says when someone asks you what your dream job is
ALT: a cartoon character is surrounded by cats and the caption says when someone asks you what your dream job is
media.tenor.com
July 29, 2025 at 10:15 AM
Reposted by Djoser Genomics
Spread the news! We are excited to expand our research team, working on cellular senescence, at the Cancer Research UK Cambridge Institute, University of Cambridge.

jobs.cam.ac.uk/job/52026/
jobs.cam.ac.uk/job/52027/
a yellow sign that says we 're hiring
ALT: a yellow sign that says we 're hiring
media.tenor.com
July 25, 2025 at 10:06 PM
Reposted by Djoser Genomics
🧬💻 We're hiring a #Software #Developer @emblebi.bsky.social! Join the @deciphergenomics.bsky.social team building tools for global rare disease diagnosis & research. Work that matters, in a collaborative environment.
👉 Apply: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
⏰ Deadline: 10 August
Software Developer
In this role, you will have the opportunity to develop domain area expertise in human genetics while working with a modern technology stack. You will design, develop and support the DECIPHER platform,...
embl.wd103.myworkdayjobs.com
July 26, 2025 at 9:34 AM