Dominique Holtappels
@dholtappels.bsky.social
Assistant Professor @ Cornell AgriTech
Plant Pathology in Controlled Environment Agriculture
Studying the ecology and evolution of plant diseases
Phages, cats, coffee and scicomm
Plant Pathology in Controlled Environment Agriculture
Studying the ecology and evolution of plant diseases
Phages, cats, coffee and scicomm
Reposted by Dominique Holtappels
So enjoyable to work with both @bkoskella.bsky.social & @dholtappels.bsky.social on this project! Which started as a brilliant idea from Britt at the Wiko, and has continued remotely since (ft also a lovely trip to Berkeley!) ☺️ yay for team science!
October 10, 2025 at 1:40 PM
So enjoyable to work with both @bkoskella.bsky.social & @dholtappels.bsky.social on this project! Which started as a brilliant idea from Britt at the Wiko, and has continued remotely since (ft also a lovely trip to Berkeley!) ☺️ yay for team science!
Reposted by Dominique Holtappels
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes www.nature.com/articles/s41... 🧬🖥️ github.com/linxingchen/...
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology
Contig overlap-based reassembly enables the generation of accurate and high-quality viral genomes from assembled metagenomes.
www.nature.com
February 9, 2024 at 2:28 PM
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes www.nature.com/articles/s41... 🧬🖥️ github.com/linxingchen/...
Reposted by Dominique Holtappels
Revised preprint:
Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients.
To support major conclusions, we repeated key analyses using qPCR instead of metagenomics to quantify phage ICP1 and V. cholerae
www.biorxiv.org/content/10.1...
Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients.
To support major conclusions, we repeated key analyses using qPCR instead of metagenomics to quantify phage ICP1 and V. cholerae
www.biorxiv.org/content/10.1...
December 7, 2023 at 5:03 PM
Revised preprint:
Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients.
To support major conclusions, we repeated key analyses using qPCR instead of metagenomics to quantify phage ICP1 and V. cholerae
www.biorxiv.org/content/10.1...
Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients.
To support major conclusions, we repeated key analyses using qPCR instead of metagenomics to quantify phage ICP1 and V. cholerae
www.biorxiv.org/content/10.1...
Reposted by Dominique Holtappels
Nice to see how the arbitrium story evolves!
Cool study in Cell Host&Microbe by @aislingbrady.bsky.social et al
Characterization of a unique repression system present in arbitrium phages of the SPbeta family
www.sciencedirect.com/science/arti...
November 30, 2023 at 9:35 AM
Nice to see how the arbitrium story evolves!
Reposted by Dominique Holtappels
Fabulous work by my colleagues - Stick'em with the pointy end ... UNLESS ...??? www.nature.com/articles/s41...
The evolution of short- and long-range weapons for bacterial competition - Nature Ecology & Evolutio...
An agent-based model suggests that bacteria use direct-contact systems for inhibiting competitors when the attacking strain is outnumbered, and long-range diffusion systems when the attacker is common...
www.nature.com
November 30, 2023 at 4:41 PM
Fabulous work by my colleagues - Stick'em with the pointy end ... UNLESS ...??? www.nature.com/articles/s41...
Reposted by Dominique Holtappels
Our paper looking into the phenomenon of domain mosaicism in phages is now out in Nature Communications. Work led by Bogna Smug together with Krzysztof Szczepaniak, @epcrocha.bsky.social and @staszekdh.bsky.social. See a short thread. 1/7
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with ...
Proteins are composed of distinct functional domains, each serving a specific role. Here, Smug et al. show that phages are able to shuffle fragments of their proteins and this predominantly occurs in ...
www.nature.com
November 28, 2023 at 1:51 PM
Our paper looking into the phenomenon of domain mosaicism in phages is now out in Nature Communications. Work led by Bogna Smug together with Krzysztof Szczepaniak, @epcrocha.bsky.social and @staszekdh.bsky.social. See a short thread. 1/7
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Dominique Holtappels
#Microsky #Phagesky
Interesting "primer for evolutionary biologists interested in studying social evolution in viruses" 👇
onlinelibrary.wiley.com/doi/10.1111/...
Interesting "primer for evolutionary biologists interested in studying social evolution in viruses" 👇
onlinelibrary.wiley.com/doi/10.1111/...
Open questions in the social lives of viruses
Social interactions among viruses are diverse and pervasive, with the potential to affect every stage of the viral lifecycle. Here, we explore some of the challenges and opportunities that these inte....
onlinelibrary.wiley.com
November 25, 2023 at 8:18 PM
#Microsky #Phagesky
Interesting "primer for evolutionary biologists interested in studying social evolution in viruses" 👇
onlinelibrary.wiley.com/doi/10.1111/...
Interesting "primer for evolutionary biologists interested in studying social evolution in viruses" 👇
onlinelibrary.wiley.com/doi/10.1111/...