Dev Majumdar
@devdoot.bsky.social
Immunology & RNA Biology at the University of Vermont. Troubleshooting biology is my happy place. http://biolab.dev // It's all fun and games and "Reg, transporting really is the safest way to travel" until somebody gets bitten by quasi-energy microbes.
KOSMOS, this week's buzzy AI scientist, posits that a coding mutation in a well-studied diabetes-related protein is functioning instead by mutated/cryptic exonic TFBS. Plausible, and totally fine to hypothesize; and word salad for an AI preprint is fine too. But horizon farther away than I thought.
November 10, 2025 at 2:02 PM
KOSMOS, this week's buzzy AI scientist, posits that a coding mutation in a well-studied diabetes-related protein is functioning instead by mutated/cryptic exonic TFBS. Plausible, and totally fine to hypothesize; and word salad for an AI preprint is fine too. But horizon farther away than I thought.
Hung up on the all black dining room with black curtains.
October 18, 2025 at 12:47 AM
Hung up on the all black dining room with black curtains.
Publish the data, overlook the code? Glam gonna glam.
July 17, 2025 at 2:38 PM
Publish the data, overlook the code? Glam gonna glam.
Evangelizing for your favorite mechanisms will never quite be the same. (Flow/Veo 2).
May 22, 2025 at 3:30 AM
Evangelizing for your favorite mechanisms will never quite be the same. (Flow/Veo 2).
NF-kB enigmas endure...
May 16, 2025 at 6:30 PM
NF-kB enigmas endure...
For now, they are offering 75% off for academics and students. Just need to contact them. They should advertise this, but I suspect it goes away with too much publicity.
May 3, 2025 at 10:28 AM
For now, they are offering 75% off for academics and students. Just need to contact them. They should advertise this, but I suspect it goes away with too much publicity.
One side is clearly winning, but still feeling pretty grateful to those folks who are out there giving quotes. If you're a celebrity scientist with a big following who has gone oddly silent, I get it, but your silence is a bit deafening.
March 28, 2025 at 3:01 PM
One side is clearly winning, but still feeling pretty grateful to those folks who are out there giving quotes. If you're a celebrity scientist with a big following who has gone oddly silent, I get it, but your silence is a bit deafening.
Same as it ever was?
March 21, 2025 at 12:38 AM
Same as it ever was?
This study focuses on proper attribution of journalism but it does seem like they're getting (measurably?) better at science pub attribution. Anecdotally, Deepseek and Perplexity have been my favorites for this, but has there been a study?
March 16, 2025 at 9:35 AM
This study focuses on proper attribution of journalism but it does seem like they're getting (measurably?) better at science pub attribution. Anecdotally, Deepseek and Perplexity have been my favorites for this, but has there been a study?
Painting *and* sculpture.
February 20, 2025 at 9:53 AM
Painting *and* sculpture.
If you're wondering if those NHEJ inhibitors are for you, seems like they're doing a great job here...
February 15, 2025 at 7:41 PM
If you're wondering if those NHEJ inhibitors are for you, seems like they're doing a great job here...
Truer words couldn't have been said about that first group meeting slide before diving in to the latest and greatest. But yes, also Severance.
January 18, 2025 at 8:18 AM
Truer words couldn't have been said about that first group meeting slide before diving in to the latest and greatest. But yes, also Severance.
Where my rabbit hole ended was this rather provocative correlation (fewer attempts at unionization, presumably gipper-related). Source (econfip.org/policy-brief...)
December 8, 2024 at 3:28 AM
Where my rabbit hole ended was this rather provocative correlation (fewer attempts at unionization, presumably gipper-related). Source (econfip.org/policy-brief...)
That we had a Noah Kahan lookalike contest at UVM makes me so happy. Clear heterogeneity in degree of effort applied.
December 6, 2024 at 9:57 AM
That we had a Noah Kahan lookalike contest at UVM makes me so happy. Clear heterogeneity in degree of effort applied.
Thinking it'd be cool to make Jeff Koons-style antibody sculptures as Christmas gifts, had Gemini generate some. Then a webapp called Rodin turns 2D images into 3D-printable STL files (green background). Very new to all this but we live in amazing times for late-night rabbit holes.
November 25, 2024 at 4:26 AM
Thinking it'd be cool to make Jeff Koons-style antibody sculptures as Christmas gifts, had Gemini generate some. Then a webapp called Rodin turns 2D images into 3D-printable STL files (green background). Very new to all this but we live in amazing times for late-night rabbit holes.
Aside from the amazing 10/12 TEM hit rate, the press release metaphor just writes itself.
November 22, 2024 at 10:19 AM
Aside from the amazing 10/12 TEM hit rate, the press release metaphor just writes itself.
Finding it harder to find papers post-Twitter. Has anyone explored use of Elicit or other AI research assistant (paper discoverers)? Would anyone feel comfortable sharing use cases or workflows?
December 9, 2023 at 3:55 PM
Finding it harder to find papers post-Twitter. Has anyone explored use of Elicit or other AI research assistant (paper discoverers)? Would anyone feel comfortable sharing use cases or workflows?
Fun stuff. Addressable nanodroplets that, amazingly, do not mix.
October 8, 2023 at 4:57 AM
Fun stuff. Addressable nanodroplets that, amazingly, do not mix.
"IL-17 expressed by TIM-4+ B cells not only enhances the severity of experimental autoimmune encephalomyelitis (EAE) and promotes allograft rejection, but also acts in an autocrine manner to prevent their conversion into IL-10-expressing B cells with regulatory function"
September 24, 2023 at 10:59 PM
"IL-17 expressed by TIM-4+ B cells not only enhances the severity of experimental autoimmune encephalomyelitis (EAE) and promotes allograft rejection, but also acts in an autocrine manner to prevent their conversion into IL-10-expressing B cells with regulatory function"
"Here, we demonstrate that the lipid globotriaosylceramide (Gb3) expressed on germinal center (GC) B cells is essential for the production of high-affinity antibodies."
September 24, 2023 at 10:56 PM
"Here, we demonstrate that the lipid globotriaosylceramide (Gb3) expressed on germinal center (GC) B cells is essential for the production of high-affinity antibodies."
Viruses (and discarded socks) are truly everywhere...
September 14, 2023 at 9:07 AM
Viruses (and discarded socks) are truly everywhere...