Demarialab
@demarialab.bsky.social
Cellular senescence and age-related pathologies group. European Research Institute for the Biology of Ageing (ERIBA), UMCG. https://demarialab.com/
Yesterday we celebrated our new paper in Advanced Science! 🎉
👉 doi.org/10.1002/advs...
Yao Lin, Boshi Wang & Mengling Huang showed that female mice accumulate more p16⁺ cells but recover better after clearance. Removing them rejuvenates liver & reduces inflammation. Congrats team! 👏
👉 doi.org/10.1002/advs...
Yao Lin, Boshi Wang & Mengling Huang showed that female mice accumulate more p16⁺ cells but recover better after clearance. Removing them rejuvenates liver & reduces inflammation. Congrats team! 👏
November 7, 2025 at 1:55 PM
Yesterday we celebrated our new paper in Advanced Science! 🎉
👉 doi.org/10.1002/advs...
Yao Lin, Boshi Wang & Mengling Huang showed that female mice accumulate more p16⁺ cells but recover better after clearance. Removing them rejuvenates liver & reduces inflammation. Congrats team! 👏
👉 doi.org/10.1002/advs...
Yao Lin, Boshi Wang & Mengling Huang showed that female mice accumulate more p16⁺ cells but recover better after clearance. Removing them rejuvenates liver & reduces inflammation. Congrats team! 👏
🎓 Wonderful to celebrate the PhD defense of Dr. Darren Baker’s student, Dr. Graves, from the Mayo Clinic, who obtained her PhD cum laude from the University of Groningen! The Demaria Lab was glad to be there to share this achievement. ❤️
#PhDDefense #AgingResearch #UMCG #ERIBA
#PhDDefense #AgingResearch #UMCG #ERIBA
October 31, 2025 at 10:49 AM
🎓 Wonderful to celebrate the PhD defense of Dr. Darren Baker’s student, Dr. Graves, from the Mayo Clinic, who obtained her PhD cum laude from the University of Groningen! The Demaria Lab was glad to be there to share this achievement. ❤️
#PhDDefense #AgingResearch #UMCG #ERIBA
#PhDDefense #AgingResearch #UMCG #ERIBA
Great to host Dr. Darren Baker (Mayo Clinic) at ERIBA! He shared exciting insights on cellular senescence in neurodegeneration & cancer, followed by great discussions and a fun lab happy hour. Inspiring science and collaboration!
#AgingResearch #ERIBA #UMCG
#AgingResearch #ERIBA #UMCG
October 31, 2025 at 10:26 AM
Great to host Dr. Darren Baker (Mayo Clinic) at ERIBA! He shared exciting insights on cellular senescence in neurodegeneration & cancer, followed by great discussions and a fun lab happy hour. Inspiring science and collaboration!
#AgingResearch #ERIBA #UMCG
#AgingResearch #ERIBA #UMCG
Since September we’ve been hosting Emilio Sosa-Diaz, a master student from the National Autonomous University of Mexico 🇲🇽 . He’ll be with us to study the role of transposable elements in single cell data from senescent cells and explore macrophage aging in the liver. We’re excited to welcome him 🔬
October 11, 2025 at 8:37 AM
Since September we’ve been hosting Emilio Sosa-Diaz, a master student from the National Autonomous University of Mexico 🇲🇽 . He’ll be with us to study the role of transposable elements in single cell data from senescent cells and explore macrophage aging in the liver. We’re excited to welcome him 🔬
🎉 ICSA Rome 2025
Our team had an incredible time at the 10th ICSA conference!
Marco gave an inspiring talk on the role of Tetraspanin 13 in senescence and aging, Myrthe shared her work via a poster, and Alessio, Pilar, and Mengling presented short talks on their senescence related projects.
Our team had an incredible time at the 10th ICSA conference!
Marco gave an inspiring talk on the role of Tetraspanin 13 in senescence and aging, Myrthe shared her work via a poster, and Alessio, Pilar, and Mengling presented short talks on their senescence related projects.
October 9, 2025 at 1:02 PM
🎉 ICSA Rome 2025
Our team had an incredible time at the 10th ICSA conference!
Marco gave an inspiring talk on the role of Tetraspanin 13 in senescence and aging, Myrthe shared her work via a poster, and Alessio, Pilar, and Mengling presented short talks on their senescence related projects.
Our team had an incredible time at the 10th ICSA conference!
Marco gave an inspiring talk on the role of Tetraspanin 13 in senescence and aging, Myrthe shared her work via a poster, and Alessio, Pilar, and Mengling presented short talks on their senescence related projects.
Exciting moments from the 2nd SenAP Symposium at Hasselt University on October 7th!
Our senior scientist, Dr. Boshi Wang, delivered a keynote talk exploring the role of CDK4/6 inhibitors in senescence induction, SASP regulation, and combinatorial cancer therapy.
Our senior scientist, Dr. Boshi Wang, delivered a keynote talk exploring the role of CDK4/6 inhibitors in senescence induction, SASP regulation, and combinatorial cancer therapy.
October 9, 2025 at 11:05 AM
Exciting moments from the 2nd SenAP Symposium at Hasselt University on October 7th!
Our senior scientist, Dr. Boshi Wang, delivered a keynote talk exploring the role of CDK4/6 inhibitors in senescence induction, SASP regulation, and combinatorial cancer therapy.
Our senior scientist, Dr. Boshi Wang, delivered a keynote talk exploring the role of CDK4/6 inhibitors in senescence induction, SASP regulation, and combinatorial cancer therapy.
🎉 Lab Retreat 2025
We had an amazing time at our retreat, full of fun, teamwork, and great memories!
This year was extra special as we also celebrated the 10-year anniversary of our lab!
Grateful for this journey and for everyone who makes it so special, a big thank you to @marcdema.bsky.social.
We had an amazing time at our retreat, full of fun, teamwork, and great memories!
This year was extra special as we also celebrated the 10-year anniversary of our lab!
Grateful for this journey and for everyone who makes it so special, a big thank you to @marcdema.bsky.social.
October 5, 2025 at 6:08 PM
🎉 Lab Retreat 2025
We had an amazing time at our retreat, full of fun, teamwork, and great memories!
This year was extra special as we also celebrated the 10-year anniversary of our lab!
Grateful for this journey and for everyone who makes it so special, a big thank you to @marcdema.bsky.social.
We had an amazing time at our retreat, full of fun, teamwork, and great memories!
This year was extra special as we also celebrated the 10-year anniversary of our lab!
Grateful for this journey and for everyone who makes it so special, a big thank you to @marcdema.bsky.social.
Exciting days at the G-JAM meeting hosted by the Fritz-Lipmann-Institut in Jena 🇩🇪! Our PhDs and Postdocs presented their latest work on cellular senescence and connected with an inspiring community of aging researchers. Many thanks to the organizers for such a stimulating event! 💥🧬 #aging #research
October 5, 2025 at 5:01 PM
Exciting days at the G-JAM meeting hosted by the Fritz-Lipmann-Institut in Jena 🇩🇪! Our PhDs and Postdocs presented their latest work on cellular senescence and connected with an inspiring community of aging researchers. Many thanks to the organizers for such a stimulating event! 💥🧬 #aging #research
🔥Exciting science at ERIBA seminar! 🔥
Our Postdoc @jamilnehme.bsky.social presented his research on cell fate decisions in response to damage and the broader implications for health and disease. Inspiring insights into life’s resilience!
#aging #cellularsenescence #science
Our Postdoc @jamilnehme.bsky.social presented his research on cell fate decisions in response to damage and the broader implications for health and disease. Inspiring insights into life’s resilience!
#aging #cellularsenescence #science
September 26, 2025 at 7:57 AM
🔥Exciting science at ERIBA seminar! 🔥
Our Postdoc @jamilnehme.bsky.social presented his research on cell fate decisions in response to damage and the broader implications for health and disease. Inspiring insights into life’s resilience!
#aging #cellularsenescence #science
Our Postdoc @jamilnehme.bsky.social presented his research on cell fate decisions in response to damage and the broader implications for health and disease. Inspiring insights into life’s resilience!
#aging #cellularsenescence #science
Since September we’ve been hosting Chiara Sasia, a PhD student from the University of Florence 🇮🇹. She’ll be with us for a few months to study the role of TREM2 in senescent microglia and its interaction with astrocytes. We’re excited to welcome her and look forward to an enriching exchange! 🧫🧪
September 22, 2025 at 8:28 PM
Since September we’ve been hosting Chiara Sasia, a PhD student from the University of Florence 🇮🇹. She’ll be with us for a few months to study the role of TREM2 in senescent microglia and its interaction with astrocytes. We’re excited to welcome her and look forward to an enriching exchange! 🧫🧪
Farewell to @magnusberglind.bsky.social 👋
After two months in our lab, it was great having you around. We really enjoyed you being part of the team, both for your work and the fun moments.
Good luck with what’s next, we’re sure you’ll do great 🚀 #labteam #cellularsenescence #aging
After two months in our lab, it was great having you around. We really enjoyed you being part of the team, both for your work and the fun moments.
Good luck with what’s next, we’re sure you’ll do great 🚀 #labteam #cellularsenescence #aging
August 22, 2025 at 2:14 PM
Farewell to @magnusberglind.bsky.social 👋
After two months in our lab, it was great having you around. We really enjoyed you being part of the team, both for your work and the fun moments.
Good luck with what’s next, we’re sure you’ll do great 🚀 #labteam #cellularsenescence #aging
After two months in our lab, it was great having you around. We really enjoyed you being part of the team, both for your work and the fun moments.
Good luck with what’s next, we’re sure you’ll do great 🚀 #labteam #cellularsenescence #aging
Starting in mid-May, Ian Davis has joined us from SUNY-ESF (Syracuse, NY). Ian is a B.Sc. student with us through mid-August and has been investigating an already-approved drug class for its potential senolytic effects in mice.
July 15, 2025 at 1:05 PM
Starting in mid-May, Ian Davis has joined us from SUNY-ESF (Syracuse, NY). Ian is a B.Sc. student with us through mid-August and has been investigating an already-approved drug class for its potential senolytic effects in mice.
Since June, we’ve been hosting @magnusberglind.bsky.social, PhD student from Copenhagen University Hospital (Hvidovre)🇩🇰.He’s with us for two months to study cells isolated from a new tissue-specific p16 reporter mouse model.We’re glad to have him and look forward to a great scientific exchange!
June 25, 2025 at 1:31 PM
Since June, we’ve been hosting @magnusberglind.bsky.social, PhD student from Copenhagen University Hospital (Hvidovre)🇩🇰.He’s with us for two months to study cells isolated from a new tissue-specific p16 reporter mouse model.We’re glad to have him and look forward to a great scientific exchange!
Farewell 🍻🫶
Last week we said goodbye to Allancer, Arianna and Chiara with a lovely lab happy hour.
Thank you for your dedication, curiosity, and bright spirit.
Wishing you all the best in your next adventures.
You'll be missed and always welcome back! 💛
#LabHappyHour #Science
Last week we said goodbye to Allancer, Arianna and Chiara with a lovely lab happy hour.
Thank you for your dedication, curiosity, and bright spirit.
Wishing you all the best in your next adventures.
You'll be missed and always welcome back! 💛
#LabHappyHour #Science
June 25, 2025 at 12:05 PM
Farewell 🍻🫶
Last week we said goodbye to Allancer, Arianna and Chiara with a lovely lab happy hour.
Thank you for your dedication, curiosity, and bright spirit.
Wishing you all the best in your next adventures.
You'll be missed and always welcome back! 💛
#LabHappyHour #Science
Last week we said goodbye to Allancer, Arianna and Chiara with a lovely lab happy hour.
Thank you for your dedication, curiosity, and bright spirit.
Wishing you all the best in your next adventures.
You'll be missed and always welcome back! 💛
#LabHappyHour #Science
On 10th April 2025, members from the Demaria lab, and others, organized the first PhD Day for PhD candidates in the theme of development and ageing. This event gave PhD candidates the opportunity to present their research, engage with their peers and become part of a vibrant academic community.
June 25, 2025 at 10:58 AM
On 10th April 2025, members from the Demaria lab, and others, organized the first PhD Day for PhD candidates in the theme of development and ageing. This event gave PhD candidates the opportunity to present their research, engage with their peers and become part of a vibrant academic community.
Congrats to @jamilnehme.bsky.social for winning an NWO XS grant at UMCG! 🧬 He’ll explore if an elephant gene that controls cell death can fight cancer and aging by enhancing the removal of damaged cells. A bold step toward unlocking nature’s secrets for healthier lives. @umcgroningen.bsky.social
June 5, 2025 at 1:10 PM
Congrats to @jamilnehme.bsky.social for winning an NWO XS grant at UMCG! 🧬 He’ll explore if an elephant gene that controls cell death can fight cancer and aging by enhancing the removal of damaged cells. A bold step toward unlocking nature’s secrets for healthier lives. @umcgroningen.bsky.social
🧬 In his latest editorial for Aging-US, Prof. Marco Demaria @marcdema.bsky.social
advocates for a transformative shift in healthcare from reactive disease management to more proactive strategies...
Read more: www.aging-us.com/article/2062...
#Healthspan #Longevity #HealthcareInnovation
advocates for a transformative shift in healthcare from reactive disease management to more proactive strategies...
Read more: www.aging-us.com/article/2062...
#Healthspan #Longevity #HealthcareInnovation
June 5, 2025 at 12:43 PM
🧬 In his latest editorial for Aging-US, Prof. Marco Demaria @marcdema.bsky.social
advocates for a transformative shift in healthcare from reactive disease management to more proactive strategies...
Read more: www.aging-us.com/article/2062...
#Healthspan #Longevity #HealthcareInnovation
advocates for a transformative shift in healthcare from reactive disease management to more proactive strategies...
Read more: www.aging-us.com/article/2062...
#Healthspan #Longevity #HealthcareInnovation
New brain on board! 🔬
Meet Vlaicu, our new MSc student from RUG who joined in December to study how hypoxia-mimetic drugs impact senescence in lung MSCs 🧬 🫁
Good luck on this exciting scientific adventure! 🚀 #CellBiology #Senescence #Hypoxia
Meet Vlaicu, our new MSc student from RUG who joined in December to study how hypoxia-mimetic drugs impact senescence in lung MSCs 🧬 🫁
Good luck on this exciting scientific adventure! 🚀 #CellBiology #Senescence #Hypoxia
June 5, 2025 at 12:12 PM
New brain on board! 🔬
Meet Vlaicu, our new MSc student from RUG who joined in December to study how hypoxia-mimetic drugs impact senescence in lung MSCs 🧬 🫁
Good luck on this exciting scientific adventure! 🚀 #CellBiology #Senescence #Hypoxia
Meet Vlaicu, our new MSc student from RUG who joined in December to study how hypoxia-mimetic drugs impact senescence in lung MSCs 🧬 🫁
Good luck on this exciting scientific adventure! 🚀 #CellBiology #Senescence #Hypoxia
🚨New student in the lab!🚨
Welcome to our MSc student Manon from RUG 🎓 Since January, she's been exploring how a fatty acid modulates cellular senescence 🧬🧪 Guided by postdoctoral researcher Pilar Picallos.
Wishing her an exciting journey into the science of aging! 🌟
#CellBiology #Senescence #Aging
Welcome to our MSc student Manon from RUG 🎓 Since January, she's been exploring how a fatty acid modulates cellular senescence 🧬🧪 Guided by postdoctoral researcher Pilar Picallos.
Wishing her an exciting journey into the science of aging! 🌟
#CellBiology #Senescence #Aging
June 5, 2025 at 11:55 AM
🚨New student in the lab!🚨
Welcome to our MSc student Manon from RUG 🎓 Since January, she's been exploring how a fatty acid modulates cellular senescence 🧬🧪 Guided by postdoctoral researcher Pilar Picallos.
Wishing her an exciting journey into the science of aging! 🌟
#CellBiology #Senescence #Aging
Welcome to our MSc student Manon from RUG 🎓 Since January, she's been exploring how a fatty acid modulates cellular senescence 🧬🧪 Guided by postdoctoral researcher Pilar Picallos.
Wishing her an exciting journey into the science of aging! 🌟
#CellBiology #Senescence #Aging
Visiting Students👩🏾🔬🧪
Since February 27, our lab has been hosting Chiara and Arianna, Erasmus Master's students from the University of Calabria (Italy).
Over 4 months, they’ll explore cellular senescence and learn new lab techniques.
A wonderful exchange of skills and scientific curiosity! 🧬🔬 #Science
Since February 27, our lab has been hosting Chiara and Arianna, Erasmus Master's students from the University of Calabria (Italy).
Over 4 months, they’ll explore cellular senescence and learn new lab techniques.
A wonderful exchange of skills and scientific curiosity! 🧬🔬 #Science
May 26, 2025 at 1:27 PM
Visiting Students👩🏾🔬🧪
Since February 27, our lab has been hosting Chiara and Arianna, Erasmus Master's students from the University of Calabria (Italy).
Over 4 months, they’ll explore cellular senescence and learn new lab techniques.
A wonderful exchange of skills and scientific curiosity! 🧬🔬 #Science
Since February 27, our lab has been hosting Chiara and Arianna, Erasmus Master's students from the University of Calabria (Italy).
Over 4 months, they’ll explore cellular senescence and learn new lab techniques.
A wonderful exchange of skills and scientific curiosity! 🧬🔬 #Science
💥ERIBA Seminar💥
🔬 On March 14, Pilar Picallos-Rabina presented her postdoc project at her 1st ERIBA seminar, unveiling how fatty acids modulate cellular senescence. Aging meets metabolism in a science-packed talk! 🧬🔥
🔬 On March 14, Pilar Picallos-Rabina presented her postdoc project at her 1st ERIBA seminar, unveiling how fatty acids modulate cellular senescence. Aging meets metabolism in a science-packed talk! 🧬🔥
May 23, 2025 at 2:26 PM
💥ERIBA Seminar💥
🔬 On March 14, Pilar Picallos-Rabina presented her postdoc project at her 1st ERIBA seminar, unveiling how fatty acids modulate cellular senescence. Aging meets metabolism in a science-packed talk! 🧬🔥
🔬 On March 14, Pilar Picallos-Rabina presented her postdoc project at her 1st ERIBA seminar, unveiling how fatty acids modulate cellular senescence. Aging meets metabolism in a science-packed talk! 🧬🔥
Thrilled to welcome Allancer Nunes 👋 Visiting postdoc from the Paul Robbins Lab at the Masonic Institute on the biology of aging and metabolism! Here for 2 months to validate the senotherapeutic activity of a new compound in mouse cell lines, with a focus on sex disparity 🧬 #senescence #aging
April 14, 2025 at 10:06 AM
Thrilled to welcome Allancer Nunes 👋 Visiting postdoc from the Paul Robbins Lab at the Masonic Institute on the biology of aging and metabolism! Here for 2 months to validate the senotherapeutic activity of a new compound in mouse cell lines, with a focus on sex disparity 🧬 #senescence #aging
On March 13, our postdoc @boshiwang.bsky.social joined the pitch competition at #This-is-UMCG-Research, presenting his project on how chemotherapy-induced senescent cells promote cancer progression. A great day to celebrate innovative science and fresh grants across UMCG’s research institutes! 🔬⚛️
April 6, 2025 at 5:11 PM
On March 13, our postdoc @boshiwang.bsky.social joined the pitch competition at #This-is-UMCG-Research, presenting his project on how chemotherapy-induced senescent cells promote cancer progression. A great day to celebrate innovative science and fresh grants across UMCG’s research institutes! 🔬⚛️
🎉 Congrats on the successful MoHAD Postdoc/Early Researcher Day, organized by postdocs @martijnrutten.bsky.social & @jamilnehme.bsky.social from our lab! An inspiring event with career talks, great presentations, lively discussions, and creative brainstorming to foster collaboration. 🚀
March 26, 2025 at 9:42 AM
🎉 Congrats on the successful MoHAD Postdoc/Early Researcher Day, organized by postdocs @martijnrutten.bsky.social & @jamilnehme.bsky.social from our lab! An inspiring event with career talks, great presentations, lively discussions, and creative brainstorming to foster collaboration. 🚀