dawnwenzel.bsky.social
@dawnwenzel.bsky.social
Biochemist at the Medical College of Wisconsin, views are my own
Reposted
Viral AlphaFold Database (VAD) is live in Science Advances

~27,000 predicted viral protein monomers & homodimers

Conserved folds across bacteria, archaea & eukaryotic viruses

New toxin–antitoxin system KreTA uncovered

Vast “functional darkness” remains uncharted

www.science.org/doi/10.1126/...
The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes
VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.
www.science.org
October 2, 2025 at 8:48 AM
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April 17, 2025 at 11:36 AM
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Best Wisconsin sign!
March 7, 2025 at 7:30 PM
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ChimeraX can run Foldseek to find similar structures, such as distantly related homologs, and analyze the results, for example, mapping all ligands onto your query structure. Here are ligands mapped onto Nipah virus G protein. www.rbvi.ucsf.edu/chimerax/dat...
March 6, 2025 at 11:06 PM
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hell yes
NEW: Letter filed in Adams case announces that ALL of the prior counsel on the case from the S.D. N.Y. U.S. Attorney’s Office are withdrawing from it.
February 14, 2025 at 11:59 PM
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Answering the call of @haesleinhuepf.bsky.social, Christian Tischer, Pete Bankhead, @kbias.bsky.social @bethcimini.bsky.social
My Fiji training notes are now FAIR. All online in an open format to download and use for teaching and training. All in Google Doc or PDF formats
bit.ly/4hkfEBF
Home
This site contains the complete version of the Fiji Training Manual that is written and maintained by Cameron Nowell of the Monash Institue of Pharmaceutical Science. This manual is provided under the...
bit.ly
February 5, 2025 at 10:57 PM
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Foldseek-Multimer—now published in @naturemethods.bsky.social—our fast multimer search tool, enables complex comparisons against the full PDB in seconds. It comes with BFMD, a collection of 300K+ predictions gathered from community projects.
📄 nature.com/articles/s41...
🌐 search.foldseek.com
February 6, 2025 at 8:25 AM
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Very excited that the lab's first paper is out! We showed that in stem cells, Aurora B controls abscission dynamics by regulating microtubules stability and MCAK recruitment. Very happy with this streamlined version of our 2024 preprint.
www.cell.com/cell-reports...
Aurora B controls microtubule stability to regulate abscission dynamics in stem cells
Mouse embryonic stem cells remain connected by bridges for hours after cell division. In this paper, Kodba et al. show that a high Aurora B activity at the bridge leads to microtubule stabilization. S...
www.cell.com
January 24, 2025 at 5:00 PM
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Did your child lose their book collection in the Los Angeles fires? Are you a teacher at a school that lost its library or your classroom library? Whether you need one book or a whole library, we can replace your books. 📚

Everyone else, please boost this post so we can connect with those in need. 🙏
January 16, 2025 at 3:35 PM
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I'm happy and humbled to take on a new role with @rcsbpdb.bsky.social. I'll be continuing David Goodsell's work on the Molecule of the Month, starting with my first article on Assembly Line Polyketide Synthases! Check it out (animation included!)
pdb101.rcsb.org/motm/301
PDB101: Molecule of the Month: Assembly Line Polyketide Synthases
Large multienzyme complexes that synthesize diverse small molecules in a stepwise manner.
pdb101.rcsb.org
January 7, 2025 at 6:32 PM
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eyes in space 👁️🌌
December 19, 2024 at 10:31 PM
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Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib
November 17, 2024 at 4:04 PM
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Want to make beautiful scientific figures? Easy!

The NIH released a library of 2000+ free scientific illustrations called *BioArt*.

Check it out! bioart.niaid.nih.gov

#AcademicSky #PsychSciSky 🧠🟦 🧪
October 30, 2024 at 9:45 AM