A huge thank you to all our collaborators ! 🙏

3/3 ZinS emerged via horizontal gene transfer of the zinP mRNA and neofunctionalization of its 3' UTR 🔄

2/3 ZinS is a dual-function sRNA encoding a small peptide, ZinP

1/3 We have revealed ZinS as the first small regulatory RNA involved in a zinc-sparing response in bacteria. ZinS (formerly RsaX20) negatively regulates Zn-dependent enzymes, including alcohol dehydrogenase to spare this essential element for S. aureus survival and virulence.