Darius Valevicius
@dariusliutas.bsky.social
Restless neuroscientist and occasional artist.
PhD candidate at Université de Montréal.
Interests include: Emotion, critical psychiatry, trauma, psychophysiology, history and phil of science, painting, drawing, music, game development
dariusliutas.com
PhD candidate at Université de Montréal.
Interests include: Emotion, critical psychiatry, trauma, psychophysiology, history and phil of science, painting, drawing, music, game development
dariusliutas.com
I would love to see an in-depth back and forth discussion on this, whether live or in writing (maybe the latter would work better for the topic).
October 31, 2025 at 1:44 PM
I would love to see an in-depth back and forth discussion on this, whether live or in writing (maybe the latter would work better for the topic).
Seems compatible with this recent paper? bsky.app/profile/cp-t...
October 26, 2025 at 4:36 PM
Seems compatible with this recent paper? bsky.app/profile/cp-t...
I felt like there must be some unspoken rule not to talk about it?
October 19, 2025 at 3:02 PM
I felt like there must be some unspoken rule not to talk about it?
I just attended a conference that involved a fair percentage of really good work, mostly in the keynotes, but around 70-80% of the poster and symposia results would be completely voided if any multiple comparisons correction was used. No one seemed the least bit worried about it!
October 19, 2025 at 3:01 PM
I just attended a conference that involved a fair percentage of really good work, mostly in the keynotes, but around 70-80% of the poster and symposia results would be completely voided if any multiple comparisons correction was used. No one seemed the least bit worried about it!
In the latter theory as far as I can gather the learning is "done by" distributed cortical regions? E.g. the metabolic cost/benefit which would constitute reward/aversion is computed by medial PFC, insula etc. (which seems like an extremely computationally intensive task)
October 14, 2025 at 6:09 PM
In the latter theory as far as I can gather the learning is "done by" distributed cortical regions? E.g. the metabolic cost/benefit which would constitute reward/aversion is computed by medial PFC, insula etc. (which seems like an extremely computationally intensive task)
In Pksp's model, behavioral learning "bottoms out" in homeostatic error signals generated in the PAG... It's not dissimilar from the predictive brain theory of LFB except that error signals (which == affects) bottom out in high-level heuristics rather than optimizations of metabolic cost and benefit
October 14, 2025 at 6:01 PM
In Pksp's model, behavioral learning "bottoms out" in homeostatic error signals generated in the PAG... It's not dissimilar from the predictive brain theory of LFB except that error signals (which == affects) bottom out in high-level heuristics rather than optimizations of metabolic cost and benefit
'What is doing the learning' in terms of brain circuits or conceptually?
October 14, 2025 at 3:20 PM
'What is doing the learning' in terms of brain circuits or conceptually?
This seems in line with Panksepp's hypothesis of dopamine/the MFB as a general-purpose system for motivated behaviour right?
I also recall reading a critique (from Solms?) of the RPE hypothesis that the whole brain responds to RPEs, so the VTA was never very special in that regard to begin with
I also recall reading a critique (from Solms?) of the RPE hypothesis that the whole brain responds to RPEs, so the VTA was never very special in that regard to begin with
October 14, 2025 at 3:15 PM
This seems in line with Panksepp's hypothesis of dopamine/the MFB as a general-purpose system for motivated behaviour right?
I also recall reading a critique (from Solms?) of the RPE hypothesis that the whole brain responds to RPEs, so the VTA was never very special in that regard to begin with
I also recall reading a critique (from Solms?) of the RPE hypothesis that the whole brain responds to RPEs, so the VTA was never very special in that regard to begin with
Or a discord server for people wanting to talk shop in their spare time? If some folks show interest I can throw one together
October 6, 2025 at 11:20 PM
Or a discord server for people wanting to talk shop in their spare time? If some folks show interest I can throw one together
I felt the part about scientific conversations taking the backseat to logistical and "academic lifestyle" conversations. Honestly the latter bores me to tears most of the time ;-; time to start a journal club I guess?
October 6, 2025 at 11:19 PM
I felt the part about scientific conversations taking the backseat to logistical and "academic lifestyle" conversations. Honestly the latter bores me to tears most of the time ;-; time to start a journal club I guess?
That was an initial thought I had, that EDA spiking/sudomotor nerve firing might correlate with the phase of low frequency BOLD oscillations. But I wonder why that would be?
October 3, 2025 at 1:57 PM
That was an initial thought I had, that EDA spiking/sudomotor nerve firing might correlate with the phase of low frequency BOLD oscillations. But I wonder why that would be?
October 2, 2025 at 7:05 PM
Breath holding in anticipation? Or neuronally induced anticipation signal? Why does the EDA spike seem to trigger/coincide with a crash in GS? Paging @danielhandwerker.bsky.social @practicalfmri.bsky.social
Paper in question: doi.org/10.1016/j.ne...
Paper in question: doi.org/10.1016/j.ne...
October 2, 2025 at 5:05 PM
Breath holding in anticipation? Or neuronally induced anticipation signal? Why does the EDA spike seem to trigger/coincide with a crash in GS? Paging @danielhandwerker.bsky.social @practicalfmri.bsky.social
Paper in question: doi.org/10.1016/j.ne...
Paper in question: doi.org/10.1016/j.ne...
I guess that is one way to put it 😅
September 28, 2025 at 2:33 PM
I guess that is one way to put it 😅
Not exactly sure how to put this but I guess I'm wondering how much of a disconnect there is between the phenomenology of peripheral vision and how we think about it conceptually, and how that's affected by mistaking beliefs for percepts
September 26, 2025 at 3:05 AM
Not exactly sure how to put this but I guess I'm wondering how much of a disconnect there is between the phenomenology of peripheral vision and how we think about it conceptually, and how that's affected by mistaking beliefs for percepts
Do we know how much is "filling in" and how much is just beliefs about what ought to be there? I recall someone arguing that the blind spot phenomenon was proof of top down predictive processing. But to me, it just registers as an absence or lack, not that anything has been "filled in".
September 26, 2025 at 3:02 AM
Do we know how much is "filling in" and how much is just beliefs about what ought to be there? I recall someone arguing that the blind spot phenomenon was proof of top down predictive processing. But to me, it just registers as an absence or lack, not that anything has been "filled in".
Dovetails well with this recent work: bsky.app/profile/tsbo...
First post on an exciting new manuscript online today @natneuro.nature.com - in collab with @lucinauddin.bsky.social and Catie Chang. We take a fresh look at the physiological dynamics associated with the global signal 🧠 ...
www.nature.com/articles/s41...
Read here:
rdcu.be/ek01F
www.nature.com/articles/s41...
Read here:
rdcu.be/ek01F
Autonomic physiological coupling of the global fMRI signal
Nature Neuroscience - The brain and body are necessarily connected. Here the authors show that brain blood flow and electrical activity are coupled with systemic physiological changes in the body.
rdcu.be
September 25, 2025 at 12:42 PM
Dovetails well with this recent work: bsky.app/profile/tsbo...
"The findings support our reframing of arousal from a discrete, one-dimensional state to a structured, organism-wide process that continuously unfolds in an abstract multidimensional mathematical space."
Has Platonism gone too far?
Cool paper though :)
Has Platonism gone too far?
Cool paper though :)
September 25, 2025 at 12:41 PM
"The findings support our reframing of arousal from a discrete, one-dimensional state to a structured, organism-wide process that continuously unfolds in an abstract multidimensional mathematical space."
Has Platonism gone too far?
Cool paper though :)
Has Platonism gone too far?
Cool paper though :)
I noticed a jump from mixed selectivity to multifunctionality in this discussion - does a complex tuning curve imply a node with multiple functions? Or a node with a function that is recruited in multiple contexts?
September 15, 2025 at 9:28 PM
I noticed a jump from mixed selectivity to multifunctionality in this discussion - does a complex tuning curve imply a node with multiple functions? Or a node with a function that is recruited in multiple contexts?
"The Trading Game" is great pop econ. But yeah this balance is something that's been on my mind a lot, all my aspirations to help people by understanding the brain / the psyche start to pale the more broke we all get...
September 15, 2025 at 12:42 PM
"The Trading Game" is great pop econ. But yeah this balance is something that's been on my mind a lot, all my aspirations to help people by understanding the brain / the psyche start to pale the more broke we all get...
Could be a motor metaphor, e.g. when feeling "up" you feel buoyant (I know you'll appreciate that term) and have a spring in your step, when feeling "down" you can't seem to muster up the energy to rise out of bed?
Neurologically it must have something to do with SEEKING system tone..?
Neurologically it must have something to do with SEEKING system tone..?
September 14, 2025 at 2:11 PM
Could be a motor metaphor, e.g. when feeling "up" you feel buoyant (I know you'll appreciate that term) and have a spring in your step, when feeling "down" you can't seem to muster up the energy to rise out of bed?
Neurologically it must have something to do with SEEKING system tone..?
Neurologically it must have something to do with SEEKING system tone..?
And these days we also use it to refer to a non-symptomatic feeling/emotion 😛
Btw, the term "autism" was originally coined to refer to a symptom of schizophrenia, as recently as the 1910s. Big semantic shift!
Btw, the term "autism" was originally coined to refer to a symptom of schizophrenia, as recently as the 1910s. Big semantic shift!
September 14, 2025 at 1:10 PM
And these days we also use it to refer to a non-symptomatic feeling/emotion 😛
Btw, the term "autism" was originally coined to refer to a symptom of schizophrenia, as recently as the 1910s. Big semantic shift!
Btw, the term "autism" was originally coined to refer to a symptom of schizophrenia, as recently as the 1910s. Big semantic shift!