Daniel Lab
@daniellab.bsky.social
PI at #HelmholtzMunich
Group leader of Type 1 Diabetes Immunology Research Unit (TDI)
https://www.helmholtz-munich.de/en/tdi
Professor of Immune Modulation at LMU
Co-Speaker of TRR355
#Tregs #Diabetes #Autoimmunity
Group leader of Type 1 Diabetes Immunology Research Unit (TDI)
https://www.helmholtz-munich.de/en/tdi
Professor of Immune Modulation at LMU
Co-Speaker of TRR355
#Tregs #Diabetes #Autoimmunity
Reposted by Daniel Lab
🔬 New study by #HelmholtzMunich, #DZD & Goethe University Frankfurt shows vidofludimus calcium may delay #Type1Diabetes by rebalancing immune cells.
👉 Read more: t1p.de/n6s0g
@daniellab.bsky.social @diabresearch-dzd.bsky.social @goetheuni.bsky.social
👉 Read more: t1p.de/n6s0g
@daniellab.bsky.social @diabresearch-dzd.bsky.social @goetheuni.bsky.social
July 29, 2025 at 7:11 AM
🔬 New study by #HelmholtzMunich, #DZD & Goethe University Frankfurt shows vidofludimus calcium may delay #Type1Diabetes by rebalancing immune cells.
👉 Read more: t1p.de/n6s0g
@daniellab.bsky.social @diabresearch-dzd.bsky.social @goetheuni.bsky.social
👉 Read more: t1p.de/n6s0g
@daniellab.bsky.social @diabresearch-dzd.bsky.social @goetheuni.bsky.social
Reposted by Daniel Lab
Immune Modulation in Metabolic Disease
A study from #HelmholtzMunich & #DZD uncovers how #Tregs link immunity & #metabolism, paving the way for immune-based therapies for #obesity & #Type2Diabetes.
Learn more:
👉 t1p.de/4uebn
#Immunology #DiabetesResearch
A study from #HelmholtzMunich & #DZD uncovers how #Tregs link immunity & #metabolism, paving the way for immune-based therapies for #obesity & #Type2Diabetes.
Learn more:
👉 t1p.de/4uebn
#Immunology #DiabetesResearch
March 21, 2025 at 12:36 PM
Immune Modulation in Metabolic Disease
A study from #HelmholtzMunich & #DZD uncovers how #Tregs link immunity & #metabolism, paving the way for immune-based therapies for #obesity & #Type2Diabetes.
Learn more:
👉 t1p.de/4uebn
#Immunology #DiabetesResearch
A study from #HelmholtzMunich & #DZD uncovers how #Tregs link immunity & #metabolism, paving the way for immune-based therapies for #obesity & #Type2Diabetes.
Learn more:
👉 t1p.de/4uebn
#Immunology #DiabetesResearch
Reposted by Daniel Lab
#ScienceNeedsHer
Inspiring Careers – Insights on Female Leadership
#HelmholtzMunich wrapped up its #AwarenessMonth #WomenAtHelmholtzMunich with the event "Inspiring Careers – Insights on Female Leadership" at Salon Luitpold in Munich.
👉 t1p.de/9jw3p
Photos: ©Milos Jakobi I Helmholtz Munich
Inspiring Careers – Insights on Female Leadership
#HelmholtzMunich wrapped up its #AwarenessMonth #WomenAtHelmholtzMunich with the event "Inspiring Careers – Insights on Female Leadership" at Salon Luitpold in Munich.
👉 t1p.de/9jw3p
Photos: ©Milos Jakobi I Helmholtz Munich
March 12, 2025 at 1:30 PM
#ScienceNeedsHer
Inspiring Careers – Insights on Female Leadership
#HelmholtzMunich wrapped up its #AwarenessMonth #WomenAtHelmholtzMunich with the event "Inspiring Careers – Insights on Female Leadership" at Salon Luitpold in Munich.
👉 t1p.de/9jw3p
Photos: ©Milos Jakobi I Helmholtz Munich
Inspiring Careers – Insights on Female Leadership
#HelmholtzMunich wrapped up its #AwarenessMonth #WomenAtHelmholtzMunich with the event "Inspiring Careers – Insights on Female Leadership" at Salon Luitpold in Munich.
👉 t1p.de/9jw3p
Photos: ©Milos Jakobi I Helmholtz Munich
Reposted by Daniel Lab
Today is #WorldObesityDay.
#Obesity is a complex condition and each individual faces distinct needs & challenges.
A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
#Obesity is a complex condition and each individual faces distinct needs & challenges.
A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
March 4, 2025 at 7:07 AM
Today is #WorldObesityDay.
#Obesity is a complex condition and each individual faces distinct needs & challenges.
A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
#Obesity is a complex condition and each individual faces distinct needs & challenges.
A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
More reasons to celebrate today! 👏 Our PhD student Sandra Dirschl won the Jury's Choice Award at the Three-Minute Thesis Competition organized by @www.helmholtz-munich.de's Research School for Diabetes. Congratulations, Sandra! 🏆
February 11, 2025 at 12:51 PM
More reasons to celebrate today! 👏 Our PhD student Sandra Dirschl won the Jury's Choice Award at the Three-Minute Thesis Competition organized by @www.helmholtz-munich.de's Research School for Diabetes. Congratulations, Sandra! 🏆
Happy International Day of Women and Girls In Science! On this day, I'm proud to acknowledge the creativity, hard work and contributions of all the women in the TDI team. Thank you for your ideas and your wonderful work!
February 11, 2025 at 8:39 AM
Happy International Day of Women and Girls In Science! On this day, I'm proud to acknowledge the creativity, hard work and contributions of all the women in the TDI team. Thank you for your ideas and your wonderful work!
Reposted by Daniel Lab
#WomenAtHelmholtzMunich
This February, we’re kicking off an awareness month for our outstanding #WomenInScience! 👏
👉 Check out inspiring thoughts, careers & leadership journeys of female researchers at #HelmholtzMunich:
t1p.de/mddsr
🌟Stay tuned & learn why #ScienceNeedsHer!
#InspiringWomen
This February, we’re kicking off an awareness month for our outstanding #WomenInScience! 👏
👉 Check out inspiring thoughts, careers & leadership journeys of female researchers at #HelmholtzMunich:
t1p.de/mddsr
🌟Stay tuned & learn why #ScienceNeedsHer!
#InspiringWomen
February 11, 2025 at 8:35 AM
#WomenAtHelmholtzMunich
This February, we’re kicking off an awareness month for our outstanding #WomenInScience! 👏
👉 Check out inspiring thoughts, careers & leadership journeys of female researchers at #HelmholtzMunich:
t1p.de/mddsr
🌟Stay tuned & learn why #ScienceNeedsHer!
#InspiringWomen
This February, we’re kicking off an awareness month for our outstanding #WomenInScience! 👏
👉 Check out inspiring thoughts, careers & leadership journeys of female researchers at #HelmholtzMunich:
t1p.de/mddsr
🌟Stay tuned & learn why #ScienceNeedsHer!
#InspiringWomen
Job alert! We're looking for a Technical Assistant for our team, with experience in molecular and cell biology techniques (e.g., PCR, ELISA, flow cytometry), and skills in managing mouse lines (FELASA certification is a plus).
Learn more and apply here:
Learn more and apply here:
Technische Assistenz - BTA/CTA/MTA (m/w/d)
jobs.helmholtz-muenchen.de
January 9, 2025 at 9:29 AM
Job alert! We're looking for a Technical Assistant for our team, with experience in molecular and cell biology techniques (e.g., PCR, ELISA, flow cytometry), and skills in managing mouse lines (FELASA certification is a plus).
Learn more and apply here:
Learn more and apply here:
Reposted by Daniel Lab
Engineering T cells with capability for a switch in specificity
www.cell.com/immunity/ful... for better homing agents, to improve safety and efficacy vs cancer and other emerging T cell interventions
www.cell.com/immunity/ful... for better homing agents, to improve safety and efficacy vs cancer and other emerging T cell interventions
T-Switch: A specificity-based engineering platform for developing safe and effective T cell therapeutics
Abdelfattah et al. developed an engineering platform (T-Switch) for the creation,
modification, and high-throughput profiling of T cell receptors (TCRs) to desired
targets, particularly self-antigens....
www.cell.com
December 3, 2024 at 4:02 PM
Engineering T cells with capability for a switch in specificity
www.cell.com/immunity/ful... for better homing agents, to improve safety and efficacy vs cancer and other emerging T cell interventions
www.cell.com/immunity/ful... for better homing agents, to improve safety and efficacy vs cancer and other emerging T cell interventions
Reposted by Daniel Lab
More #evidence for the existence of #CD8 #Regulatory #Tcells www.nature.com/articles/s41... Check our previous paper also> #KIR+CD8+ #T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 | Science www.science.org/doi/10.1126/...
Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma - Nature Immunology
Tumor-antigen-specific CD8+ T cells are generally thought to help fight against cancer, but here the authors identify a subpopulation of CD8+ T cells that are associated with a poor clinical outcome i...
www.nature.com
December 1, 2024 at 12:00 PM
More #evidence for the existence of #CD8 #Regulatory #Tcells www.nature.com/articles/s41... Check our previous paper also> #KIR+CD8+ #T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 | Science www.science.org/doi/10.1126/...
Excited to participate in next week's workshop on T cell diversity at the Bayerische Akademie der Wissenschaften @badw.de and present our work on regulatory T cells in diabetes. Don't miss it!
#Tregs #Immunology #DiabetesResearch @www.helmholtz-munich.de
#Tregs #Immunology #DiabetesResearch @www.helmholtz-munich.de
#Workshop: T Cell Diversity: Separating Facts from Fiction | 2 December, 9 AM: badw.de/fileadmin/ev...
#Tcells #Medizin #JungesKolleg #Mikrobiologie
#Tcells #Medizin #JungesKolleg #Mikrobiologie
November 29, 2024 at 10:10 AM
Excited to participate in next week's workshop on T cell diversity at the Bayerische Akademie der Wissenschaften @badw.de and present our work on regulatory T cells in diabetes. Don't miss it!
#Tregs #Immunology #DiabetesResearch @www.helmholtz-munich.de
#Tregs #Immunology #DiabetesResearch @www.helmholtz-munich.de
Reposted by Daniel Lab
Cancer escapes immunotherapies by mutating its surface, meaning even groundbreaking #CARTCell therapies fail too often. But what if #GenerativeAI could design CAR-T with de novo binders faster, targeting resistant tumors? 🧵 www.biorxiv.org/content/10.1... (1)
November 26, 2024 at 1:36 PM
Cancer escapes immunotherapies by mutating its surface, meaning even groundbreaking #CARTCell therapies fail too often. But what if #GenerativeAI could design CAR-T with de novo binders faster, targeting resistant tumors? 🧵 www.biorxiv.org/content/10.1... (1)
Reposted by Daniel Lab
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
Reposted by Daniel Lab
T cells that have not undergone MHC selection can bind soluble antigens, such as proteins or peptides, without the need for MHC presentation. 😱😱https://www.sciencedirect.com/science/article/pii/S1074761311005206
November 26, 2024 at 2:30 AM
T cells that have not undergone MHC selection can bind soluble antigens, such as proteins or peptides, without the need for MHC presentation. 😱😱https://www.sciencedirect.com/science/article/pii/S1074761311005206
Reposted by Daniel Lab
🧬 New in @Nature: Our team found that fat cells keep a “memory” of their previous obese state even after weight loss, helping explain why maintaining weight loss is so challenging. Excited to share this work!!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
www.nature.com
November 19, 2024 at 5:12 AM
🧬 New in @Nature: Our team found that fat cells keep a “memory” of their previous obese state even after weight loss, helping explain why maintaining weight loss is so challenging. Excited to share this work!!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Daniel Lab
To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny app for interactive exploration. Check it out! 👇
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...
November 23, 2024 at 1:31 PM
To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny app for interactive exploration. Check it out! 👇
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...
Hello, #Bluesky community! 🌟
We are TDI (Type 1 Diabetes Immunology) at #HelmholtzMunich. Our research focuses on understanding the role of #Tregs in autoimmune diseases such as #Type1Diabetes. Excited to reconnect with peers here and forge new connections with #immunologists worldwide!🙌
We are TDI (Type 1 Diabetes Immunology) at #HelmholtzMunich. Our research focuses on understanding the role of #Tregs in autoimmune diseases such as #Type1Diabetes. Excited to reconnect with peers here and forge new connections with #immunologists worldwide!🙌
November 22, 2024 at 10:22 AM
Hello, #Bluesky community! 🌟
We are TDI (Type 1 Diabetes Immunology) at #HelmholtzMunich. Our research focuses on understanding the role of #Tregs in autoimmune diseases such as #Type1Diabetes. Excited to reconnect with peers here and forge new connections with #immunologists worldwide!🙌
We are TDI (Type 1 Diabetes Immunology) at #HelmholtzMunich. Our research focuses on understanding the role of #Tregs in autoimmune diseases such as #Type1Diabetes. Excited to reconnect with peers here and forge new connections with #immunologists worldwide!🙌
Reposted by Daniel Lab
Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Wonderful to see the #immunology community growing here.
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
November 19, 2024 at 12:33 AM
Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Below are the links
If you're an immunologist and I have missed you so far, let me know 🧪
go.bsky.app/PY5tCas
go.bsky.app/FmERUoD
go.bsky.app/6aT6qDS
Reposted by Daniel Lab
November 18, 2024 at 5:11 AM