Daniel De Carvalho
@daniel-decarvalho.bsky.social
Ten years ago, we discovered that reactivating transposable elements triggers an antiviral state in cancer cells, a process we named viral mimicry, unmasking tumors to the immune system (Roulois, Cell 2015).
November 7, 2025 at 9:38 PM
Ten years ago, we discovered that reactivating transposable elements triggers an antiviral state in cancer cells, a process we named viral mimicry, unmasking tumors to the immune system (Roulois, Cell 2015).
Reposted by Daniel De Carvalho
We are thrilled to have Daniel De Carvalho (@daniel-decarvalho.bsky.social) from Princess Margaret Cancer Centre / University of Toronto as our Keynote speaker at #EREHD25. What a way to close 3 days of wonderful science. Thank you for being with us in Mexico Daniel!
November 6, 2025 at 12:16 AM
We are thrilled to have Daniel De Carvalho (@daniel-decarvalho.bsky.social) from Princess Margaret Cancer Centre / University of Toronto as our Keynote speaker at #EREHD25. What a way to close 3 days of wonderful science. Thank you for being with us in Mexico Daniel!
Reposted by Daniel De Carvalho
Today, Gairdner hosted the 2025 Laureate Lectures — a highlight of #GairdnerScienceWeek. All eight laureates shared the stories behind their award-winning science, alongside talks from two Early Career Investigators driving the future of discovery. #GairdnerAwards
October 23, 2025 at 9:18 PM
Today, Gairdner hosted the 2025 Laureate Lectures — a highlight of #GairdnerScienceWeek. All eight laureates shared the stories behind their award-winning science, alongside talks from two Early Career Investigators driving the future of discovery. #GairdnerAwards
Excited to have this paper out today!
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark of disease is transcription of pathogen-associated molecular
patterns from within the genome–known as viral mimicry. We propose a statistical physics
framework to measure “selecti...
www.cell.com
September 26, 2025 at 2:36 PM
Excited to have this paper out today!
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape."
It was a fun and productive collaboration with Benjamin Greenbaum John LaCava, Simona Cocco, Petr Šulc and many others!
www.cell.com/cell-genomic...
Reposted by Daniel De Carvalho
Are you currently in the ERE related field & want to find new collaborative opportunities? Join our Chairs @chiappinellilab.bsky.social, @shenhui1986.bsky.social, Ting & Tao at #EREHD25 this Nov!
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
July 17, 2025 at 3:23 PM
Are you currently in the ERE related field & want to find new collaborative opportunities? Join our Chairs @chiappinellilab.bsky.social, @shenhui1986.bsky.social, Ting & Tao at #EREHD25 this Nov!
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
Reposted by Daniel De Carvalho
Don't forget to register for #EREHD25! Our talk submission deadline has been extended to 12 JUNE 2025, so submit your abstract today to join our incredible speaker line up in Mexico this November 🏖️☀️
🔗 bit.ly/4kHWbw0
🔗 bit.ly/4kHWbw0
June 4, 2025 at 11:51 AM
Don't forget to register for #EREHD25! Our talk submission deadline has been extended to 12 JUNE 2025, so submit your abstract today to join our incredible speaker line up in Mexico this November 🏖️☀️
🔗 bit.ly/4kHWbw0
🔗 bit.ly/4kHWbw0
Risky moves: Can blocking “jumping genes” treat diseases and aging?
Great piece in Science Magazine highlighting recent efforts to understand and target transposons—also known as "jumping genes"—in human disease and aging.
Great piece in Science Magazine highlighting recent efforts to understand and target transposons—also known as "jumping genes"—in human disease and aging.
April 18, 2025 at 7:43 PM
Risky moves: Can blocking “jumping genes” treat diseases and aging?
Great piece in Science Magazine highlighting recent efforts to understand and target transposons—also known as "jumping genes"—in human disease and aging.
Great piece in Science Magazine highlighting recent efforts to understand and target transposons—also known as "jumping genes"—in human disease and aging.
Thank you @gairdnerawards.bsky.social! I'm truly humbled and grateful for this recognition. Science is never a solo journey and this award reflects the hard work, creativity, and persistence of many amazing scientists I had the privilege to work with.
Congratulations to the 2025 Canada Gairdner Award laureates! This year’s laureates represent some of the world’s most significant biomedical and global health research and discoveries.
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
April 15, 2025 at 8:18 PM
Thank you @gairdnerawards.bsky.social! I'm truly humbled and grateful for this recognition. Science is never a solo journey and this award reflects the hard work, creativity, and persistence of many amazing scientists I had the privilege to work with.
Reposted by Daniel De Carvalho
The brain trust with a difference: 2025 Gairdner award winners have taken big strides in the U.S., at a time when Trump-era cuts cast doubt on the future, by @ivansemeniuk.bsky.social @jenniferyang.bsky.social www.theglobeandmail.com/canada/artic...
@theglobeandmail.com @gairdnerawards.bsky.social
@theglobeandmail.com @gairdnerawards.bsky.social
In a time of despair for U.S. scientists, Gairdner Award winners shine brighter than usual
The winners of this year’s Canadian science prizes are all based in the United States, where Trump-era cutbacks to research and medical regulation have sown doubt in the future
www.theglobeandmail.com
April 11, 2025 at 12:26 PM
The brain trust with a difference: 2025 Gairdner award winners have taken big strides in the U.S., at a time when Trump-era cuts cast doubt on the future, by @ivansemeniuk.bsky.social @jenniferyang.bsky.social www.theglobeandmail.com/canada/artic...
@theglobeandmail.com @gairdnerawards.bsky.social
@theglobeandmail.com @gairdnerawards.bsky.social
Reposted by Daniel De Carvalho
Congratulations to the 2025 Canada Gairdner Award laureates! This year’s laureates represent some of the world’s most significant biomedical and global health research and discoveries.
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
April 11, 2025 at 2:26 PM
Congratulations to the 2025 Canada Gairdner Award laureates! This year’s laureates represent some of the world’s most significant biomedical and global health research and discoveries.
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
Learn more about their award-winning research here: gairdner.org/resource-hub...
#GairdnerAwards
Reposted by Daniel De Carvalho
New Links: Cancer and Immune Evasion
Cancer cells without the tumor suppressor protein p53 become more resistant to the body's immune response and more likely to survive. A study led by Dr. Daniel De Carvalho at UHN’s Princess Margaret Cancer Centre.
www.uhnresearch.ca/news/new-lin...
Cancer cells without the tumor suppressor protein p53 become more resistant to the body's immune response and more likely to survive. A study led by Dr. Daniel De Carvalho at UHN’s Princess Margaret Cancer Centre.
www.uhnresearch.ca/news/new-lin...
March 17, 2025 at 5:09 PM
New Links: Cancer and Immune Evasion
Cancer cells without the tumor suppressor protein p53 become more resistant to the body's immune response and more likely to survive. A study led by Dr. Daniel De Carvalho at UHN’s Princess Margaret Cancer Centre.
www.uhnresearch.ca/news/new-lin...
Cancer cells without the tumor suppressor protein p53 become more resistant to the body's immune response and more likely to survive. A study led by Dr. Daniel De Carvalho at UHN’s Princess Margaret Cancer Centre.
www.uhnresearch.ca/news/new-lin...
Happy to see this paper out!
Scientists @pmresearch-uhn.bsky.social have uncovered how cancer can evade immune defenses after losing a key tumour-suppressing gene. These findings implicate repetitive elements in DNA and may unlock new targets for cancer interception.
Read more ➡️ www.uhnresearch.ca/news/new-lin...
Read more ➡️ www.uhnresearch.ca/news/new-lin...
February 25, 2025 at 4:16 PM
Happy to see this paper out!
Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery: aacrjournals.org/cancerdiscov...
Chronic viral mimicry induction following p53 loss promotes immune evasion
Abstract. Epigenetic therapies facilitate transcription of immunogenic repetitive elements that cull cancer cells through ‘viral mimicry’ responses. Paradoxically, cancer-initiating events also facili...
aacrjournals.org
January 17, 2025 at 2:27 PM
Our recent work on Viral mimicry escape in Ovarian Cancer is out at Cancer Discovery: aacrjournals.org/cancerdiscov...
Reposted by Daniel De Carvalho
Now online in Cancer Discovery: Chronic #ViralMimicry Induction Following #p53 Loss Promotes Immune Evasion - by @cishak.bsky.social, Sajid Marhon, @daniel-decarvalho.bsky.social, and colleagues @pmresearch-uhn.bsky.social @mdanderson.bsky.social doi.org/10.1158/2159...
January 7, 2025 at 4:26 PM
Now online in Cancer Discovery: Chronic #ViralMimicry Induction Following #p53 Loss Promotes Immune Evasion - by @cishak.bsky.social, Sajid Marhon, @daniel-decarvalho.bsky.social, and colleagues @pmresearch-uhn.bsky.social @mdanderson.bsky.social doi.org/10.1158/2159...