Dan Grimes
@dangrimes.bsky.social
Biologist asking how the embryo makes the heart and gut asymmetric but keeps the spine and limbs symmetric. Arsenal fan.
Human disease | Scoliosis | Zebrafish | Cilia | DevBio | EvoDevo
Professor @ University of Oregon — https://www.grimes-lab.com
Human disease | Scoliosis | Zebrafish | Cilia | DevBio | EvoDevo
Professor @ University of Oregon — https://www.grimes-lab.com
As a big soccer fan, I'm so glad to see so many soccer subreddits calling for a stop to linking 'news' from that other place.
January 21, 2025 at 7:58 PM
As a big soccer fan, I'm so glad to see so many soccer subreddits calling for a stop to linking 'news' from that other place.
Still time to apply for @uoregon.bsky.social Summer Program for Undergraduate Research — a paid 10-week research opportunity this summer for undergrads in the life sciences.
Details in the flyer below.
Please share.
Details in the flyer below.
Please share.
January 21, 2025 at 5:50 PM
Still time to apply for @uoregon.bsky.social Summer Program for Undergraduate Research — a paid 10-week research opportunity this summer for undergrads in the life sciences.
Details in the flyer below.
Please share.
Details in the flyer below.
Please share.
For #FluorescenceFriday, here's the spinal canal of a zebrafish embryo filled with #cilia (cyan).
November 22, 2024 at 7:50 PM
For #FluorescenceFriday, here's the spinal canal of a zebrafish embryo filled with #cilia (cyan).
"The overriding ambition (of Biology research) should be to capture meaning, rather than simply catalogue complexity"
— from Paul Nurse's charming book What is Life?
— from Paul Nurse's charming book What is Life?
November 22, 2024 at 5:43 PM
"The overriding ambition (of Biology research) should be to capture meaning, rather than simply catalogue complexity"
— from Paul Nurse's charming book What is Life?
— from Paul Nurse's charming book What is Life?
Scoliosis is a common condition in which the spine curves to the side and rotates, often onsetting during adolescence.
In our lab, we generate zebrafish with scoliosis-like spinal curves to try to understand the causes of this disease.
In our lab, we generate zebrafish with scoliosis-like spinal curves to try to understand the causes of this disease.
November 21, 2024 at 10:10 PM
Scoliosis is a common condition in which the spine curves to the side and rotates, often onsetting during adolescence.
In our lab, we generate zebrafish with scoliosis-like spinal curves to try to understand the causes of this disease.
In our lab, we generate zebrafish with scoliosis-like spinal curves to try to understand the causes of this disease.
I always liked this quote in defense of basic science:
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
November 20, 2024 at 8:41 PM
I always liked this quote in defense of basic science:
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
Many congratulations to Professor Judith Eisen @uoregon.bsky.social for winning the Streisinger Award for "sustained and foundational" work in the zebrafish field. Well deserved!
April 12, 2024 at 7:48 PM
Many congratulations to Professor Judith Eisen @uoregon.bsky.social for winning the Streisinger Award for "sustained and foundational" work in the zebrafish field. Well deserved!
Arturo Rosenblueth was a pioneer of cybernetics and, along with Norbert Wiener, had this to say:
"The price of metaphor is eternal vigilance".
Let's remember that metaphors are useful for thinking and discussing science, but they are not reality.
"The price of metaphor is eternal vigilance".
Let's remember that metaphors are useful for thinking and discussing science, but they are not reality.
February 12, 2024 at 10:38 PM
Arturo Rosenblueth was a pioneer of cybernetics and, along with Norbert Wiener, had this to say:
"The price of metaphor is eternal vigilance".
Let's remember that metaphors are useful for thinking and discussing science, but they are not reality.
"The price of metaphor is eternal vigilance".
Let's remember that metaphors are useful for thinking and discussing science, but they are not reality.
I always liked this quote in defense of basic science:
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
January 18, 2024 at 6:25 PM
I always liked this quote in defense of basic science:
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
"To feed applied science by starving basic science is like economizing on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles".
— George Porter
Random thought:
Playing a game, one person says a word and the next person makes a new word by changing only a single letter:
E.g. Rain — Raid — Paid — Pain — Gain — Grin — Grit — etc.
Can all 4-letter words in the dictionary be connected like this? Do some miss out? How many?
Playing a game, one person says a word and the next person makes a new word by changing only a single letter:
E.g. Rain — Raid — Paid — Pain — Gain — Grin — Grit — etc.
Can all 4-letter words in the dictionary be connected like this? Do some miss out? How many?
January 16, 2024 at 6:56 PM
Random thought:
Playing a game, one person says a word and the next person makes a new word by changing only a single letter:
E.g. Rain — Raid — Paid — Pain — Gain — Grin — Grit — etc.
Can all 4-letter words in the dictionary be connected like this? Do some miss out? How many?
Playing a game, one person says a word and the next person makes a new word by changing only a single letter:
E.g. Rain — Raid — Paid — Pain — Gain — Grin — Grit — etc.
Can all 4-letter words in the dictionary be connected like this? Do some miss out? How many?
And another came down and landed on my neighbor's deck and roof. They're okay.
@uoregon.bsky.social is closed for the day. Stay safe everyone!
@uoregon.bsky.social is closed for the day. Stay safe everyone!
January 14, 2024 at 10:02 PM
And another came down and landed on my neighbor's deck and roof. They're okay.
@uoregon.bsky.social is closed for the day. Stay safe everyone!
@uoregon.bsky.social is closed for the day. Stay safe everyone!
But also very dangerous.
One tree came down and is blocking the road, the only exit to my cul-de-sac.
One tree came down and is blocking the road, the only exit to my cul-de-sac.
January 14, 2024 at 10:00 PM
But also very dangerous.
One tree came down and is blocking the road, the only exit to my cul-de-sac.
One tree came down and is blocking the road, the only exit to my cul-de-sac.
It's very cold and strikingly beautiful in Eugene, Oregon, today.
January 14, 2024 at 10:00 PM
It's very cold and strikingly beautiful in Eugene, Oregon, today.
I watched The Wizard of Oz over Christmas, and last night the sequel, Return to Oz.
I'm not sure what I expected from the sequel, but it certainly wasn't this terrifying Foucauldian nightmare about childhood mental illness at the turn of the century
A "children's" horror movie!
I'm not sure what I expected from the sequel, but it certainly wasn't this terrifying Foucauldian nightmare about childhood mental illness at the turn of the century
A "children's" horror movie!
January 9, 2024 at 11:06 PM
I watched The Wizard of Oz over Christmas, and last night the sequel, Return to Oz.
I'm not sure what I expected from the sequel, but it certainly wasn't this terrifying Foucauldian nightmare about childhood mental illness at the turn of the century
A "children's" horror movie!
I'm not sure what I expected from the sequel, but it certainly wasn't this terrifying Foucauldian nightmare about childhood mental illness at the turn of the century
A "children's" horror movie!
Paid 10-week summer research opportunity for life science undergraduates at University of Oregon @uoregon.bsky.social.
Our American Heart Association-sponsored prepares fellows for life science careers, and includes mentored research, training workshops and networking opportunities.
Please share!
Our American Heart Association-sponsored prepares fellows for life science careers, and includes mentored research, training workshops and networking opportunities.
Please share!
January 8, 2024 at 6:27 PM
Paid 10-week summer research opportunity for life science undergraduates at University of Oregon @uoregon.bsky.social.
Our American Heart Association-sponsored prepares fellows for life science careers, and includes mentored research, training workshops and networking opportunities.
Please share!
Our American Heart Association-sponsored prepares fellows for life science careers, and includes mentored research, training workshops and networking opportunities.
Please share!
12 asymmetric animals, bonus number 13: the Dahu
The Dahu is a goat-like creature from Southern France.
Amazingly, Dahu legs on one side (either left or right) are longer than its legs on the other side… this means the Dahu can only walk around mountains in one direction!
The Dahu is a goat-like creature from Southern France.
Amazingly, Dahu legs on one side (either left or right) are longer than its legs on the other side… this means the Dahu can only walk around mountains in one direction!
January 5, 2024 at 6:42 PM
12 asymmetric animals, bonus number 13: the Dahu
The Dahu is a goat-like creature from Southern France.
Amazingly, Dahu legs on one side (either left or right) are longer than its legs on the other side… this means the Dahu can only walk around mountains in one direction!
The Dahu is a goat-like creature from Southern France.
Amazingly, Dahu legs on one side (either left or right) are longer than its legs on the other side… this means the Dahu can only walk around mountains in one direction!
12 asymmetric animals, day 12: slugs
Land slugs breathe air through a pore called a pnemostome, an opening which connects to the animals single lung.
This breathing pore is always on the right side, as exemplified here by the European red slug.
Land slugs breathe air through a pore called a pnemostome, an opening which connects to the animals single lung.
This breathing pore is always on the right side, as exemplified here by the European red slug.
January 4, 2024 at 6:48 PM
12 asymmetric animals, day 12: slugs
Land slugs breathe air through a pore called a pnemostome, an opening which connects to the animals single lung.
This breathing pore is always on the right side, as exemplified here by the European red slug.
Land slugs breathe air through a pore called a pnemostome, an opening which connects to the animals single lung.
This breathing pore is always on the right side, as exemplified here by the European red slug.
12 asymmetric animals, day 11: Honey badger
Honey badgers are found in Africa, Southwest Asia and India.
The subspecies signata, also called the speckled ratel and found in Sierra Leone, has asymmetric teeth, with an extra lower molar on the left side of the jaw.
Honey badgers are found in Africa, Southwest Asia and India.
The subspecies signata, also called the speckled ratel and found in Sierra Leone, has asymmetric teeth, with an extra lower molar on the left side of the jaw.
January 4, 2024 at 5:52 AM
12 asymmetric animals, day 11: Honey badger
Honey badgers are found in Africa, Southwest Asia and India.
The subspecies signata, also called the speckled ratel and found in Sierra Leone, has asymmetric teeth, with an extra lower molar on the left side of the jaw.
Honey badgers are found in Africa, Southwest Asia and India.
The subspecies signata, also called the speckled ratel and found in Sierra Leone, has asymmetric teeth, with an extra lower molar on the left side of the jaw.
12 asymmetric animals, day 10: P. microlepis
This cichlid fish has an asymmetric mouth, twisted either to the left or right.
Both left-sided and right-sided morphs live together in Lake Tanganyika.
This cichlid fish has an asymmetric mouth, twisted either to the left or right.
Both left-sided and right-sided morphs live together in Lake Tanganyika.
January 2, 2024 at 2:33 PM
12 asymmetric animals, day 10: P. microlepis
This cichlid fish has an asymmetric mouth, twisted either to the left or right.
Both left-sided and right-sided morphs live together in Lake Tanganyika.
This cichlid fish has an asymmetric mouth, twisted either to the left or right.
Both left-sided and right-sided morphs live together in Lake Tanganyika.
12 asymmetric animals, day 9: cockeyed squid
This deep-sea squid has a small right eye which faces downwards, scanning for bioluminescence below.
The left eye, around twice the size of the right, bulges out of the head with a prominent yellow lens to see ambient sunlight.
This deep-sea squid has a small right eye which faces downwards, scanning for bioluminescence below.
The left eye, around twice the size of the right, bulges out of the head with a prominent yellow lens to see ambient sunlight.
January 1, 2024 at 12:46 PM
12 asymmetric animals, day 9: cockeyed squid
This deep-sea squid has a small right eye which faces downwards, scanning for bioluminescence below.
The left eye, around twice the size of the right, bulges out of the head with a prominent yellow lens to see ambient sunlight.
This deep-sea squid has a small right eye which faces downwards, scanning for bioluminescence below.
The left eye, around twice the size of the right, bulges out of the head with a prominent yellow lens to see ambient sunlight.
12 asymmetric animals, day 8: Iwasaki's snail-eater
This species of snake has asymmetric jaws, with more teeth on the right than the left.
This helps the snake eat its major food source, snails with dextral (clockwise coiled) shells.
For the snails, it's good to be sinister.
This species of snake has asymmetric jaws, with more teeth on the right than the left.
This helps the snake eat its major food source, snails with dextral (clockwise coiled) shells.
For the snails, it's good to be sinister.
December 31, 2023 at 12:41 PM
12 asymmetric animals, day 8: Iwasaki's snail-eater
This species of snake has asymmetric jaws, with more teeth on the right than the left.
This helps the snake eat its major food source, snails with dextral (clockwise coiled) shells.
For the snails, it's good to be sinister.
This species of snake has asymmetric jaws, with more teeth on the right than the left.
This helps the snake eat its major food source, snails with dextral (clockwise coiled) shells.
For the snails, it's good to be sinister.
12 asymmetric animals, day 7: sperm whale
The right nostril of sperm whales is part of the "phonic lip" used to make the loudest sounds in the animal kingdom.
While the left nostril is on top of the head (still offset to the left) and is used as a blowhole.
The right nostril of sperm whales is part of the "phonic lip" used to make the loudest sounds in the animal kingdom.
While the left nostril is on top of the head (still offset to the left) and is used as a blowhole.
December 30, 2023 at 12:45 PM
12 asymmetric animals, day 7: sperm whale
The right nostril of sperm whales is part of the "phonic lip" used to make the loudest sounds in the animal kingdom.
While the left nostril is on top of the head (still offset to the left) and is used as a blowhole.
The right nostril of sperm whales is part of the "phonic lip" used to make the loudest sounds in the animal kingdom.
While the left nostril is on top of the head (still offset to the left) and is used as a blowhole.
Congratulations to Prof. Liz Robertson for being appointed CBE (Commander of the Order of the British Empire).
Liz has made several significant contributions to mouse embryology and genetics including how to introduce mutations into the germline using engineered stem cells.
Liz has made several significant contributions to mouse embryology and genetics including how to introduce mutations into the germline using engineered stem cells.
December 30, 2023 at 12:28 PM
Congratulations to Prof. Liz Robertson for being appointed CBE (Commander of the Order of the British Empire).
Liz has made several significant contributions to mouse embryology and genetics including how to introduce mutations into the germline using engineered stem cells.
Liz has made several significant contributions to mouse embryology and genetics including how to introduce mutations into the germline using engineered stem cells.
12 asymmetric animals, day 6: barn owl
Barn owls show ear asymmetry, with the left ear opening being located higher on the head than the right.
This asymmetry contributes to the owls remarkable ability to localize sounds.
Barn owls show ear asymmetry, with the left ear opening being located higher on the head than the right.
This asymmetry contributes to the owls remarkable ability to localize sounds.
December 29, 2023 at 12:01 PM
12 asymmetric animals, day 6: barn owl
Barn owls show ear asymmetry, with the left ear opening being located higher on the head than the right.
This asymmetry contributes to the owls remarkable ability to localize sounds.
Barn owls show ear asymmetry, with the left ear opening being located higher on the head than the right.
This asymmetry contributes to the owls remarkable ability to localize sounds.
12 asymmetric animals, day 5: fiddler crabs
Male fiddler crabs have a large 'major' claw and a small 'minor' claw. The major claw is used for display signals and fighting.
If a fiddler crab loses its major claw, it will grow a new one on the opposite side.
Male fiddler crabs have a large 'major' claw and a small 'minor' claw. The major claw is used for display signals and fighting.
If a fiddler crab loses its major claw, it will grow a new one on the opposite side.
December 28, 2023 at 2:20 PM
12 asymmetric animals, day 5: fiddler crabs
Male fiddler crabs have a large 'major' claw and a small 'minor' claw. The major claw is used for display signals and fighting.
If a fiddler crab loses its major claw, it will grow a new one on the opposite side.
Male fiddler crabs have a large 'major' claw and a small 'minor' claw. The major claw is used for display signals and fighting.
If a fiddler crab loses its major claw, it will grow a new one on the opposite side.