📅 Join our Q&A drop-in on June 19 at 3pm BST to explore the new features and ask questions:
🔗 www.linkedin.com/events/25-06...

📰 Read more on our blog:
🔗 blog.opentargets.org/open-targets...

Thanks @helenacornu.bsky.social for the infographic!

Every update helps complete the puzzle 🧩 of target discovery.

Huge thanks to our data providers, partners, and the entire Open Targets team for their tireless work 🙏

🥐 We’ve also redesigned the data downloads section — now built on the ML Commons Croissant standard.

Better documentation + improved AI-readiness = easier use for researchers and developers alike.

More highlights from the release:
🧬 New gene burden studies
💊 Expanded pharmacogenetics annotations
🧠 Interacting protein evidence from IntAct, Reactome, SIGNOR, STRING
🔬 First look at our molecular structure viewers!

Over the past 3 months, we’ve added GWAS from:

VA Million Veteran Program

210+ publications
Including the Nature meta-analysis of osteoarthritis (April 2024) 🧠

All integrated + contextualised with existing data + functional genomics.

🧬 One of our big promises with bringing Open Targets Genetics to the Platform was keeping post-GWAS analysis fresh and integrated.

This release brings a 36% increase in GWAS credible sets, thanks to collaboration with the @gwascatalog.bsky.social and enhanced pipelines.

We might not get everything right from the first shot. Still, we hope that by providing an open framework and the community's help, we could consolidate our collective understanding of disease-causing genetics. Stay tuned!

The merged product will bring the best of both worlds in a single web application, covering all journeys from identifying the likely causal signals to the prioritising factors relevant to target progression

This update will power our current target identification coverage, as well as the mechanistic interpretation and biological context

The update will include a refreshed post-GWAS analysis covering state-of-the-art data and methodologies, resulting on 2.5M GWAS and molQTL credible sets, colocalisation analysis and L2G predictions

Instarted making a list the other day, with the help of others adding their own faves: github.com/MichelNivard...