James Hemp
@cyan0bacteria.bsky.social
Neuroimmune axis, mucosal immunology, microbial ecology and evolution, geobiology.
Anti-fascist. Apparently I live in a country where that has to be explicitly stated.
Anti-fascist. Apparently I live in a country where that has to be explicitly stated.
To be fair there is nothing covert about it.
November 11, 2025 at 10:20 PM
To be fair there is nothing covert about it.
It's honestly surprising that one person can be so ignorant about absolutely everything. The effort it takes to be this stupid must be exhausting.
November 8, 2025 at 6:37 PM
It's honestly surprising that one person can be so ignorant about absolutely everything. The effort it takes to be this stupid must be exhausting.
He will meet exactly zero of the stated targets.
November 7, 2025 at 7:33 AM
He will meet exactly zero of the stated targets.
The dumbest fucker in every room.
November 6, 2025 at 8:24 AM
The dumbest fucker in every room.
We have been starting our neuroimmune axis patients on low doses and then working up if needed. Many have noticed improvements. Good luck with the trial!
November 1, 2025 at 1:11 AM
We have been starting our neuroimmune axis patients on low doses and then working up if needed. Many have noticed improvements. Good luck with the trial!
What dosing is being used?
October 31, 2025 at 7:11 AM
What dosing is being used?
OpenAI literally offers nothing useful for humanity.
October 17, 2025 at 8:32 PM
OpenAI literally offers nothing useful for humanity.
I ran a clinical trial for Vyvgart and we use it in many patients. Send me DM and I'll try to answer any specific questions you have.
October 17, 2025 at 12:54 AM
I ran a clinical trial for Vyvgart and we use it in many patients. Send me DM and I'll try to answer any specific questions you have.
3. I'm actually an expert on topic X. LLMs produce random results that are less than useless (actually dangerous in many cases). Models designed for specific use cases can be very powerful. However, general AGI doesn't exist.
October 17, 2025 at 12:38 AM
3. I'm actually an expert on topic X. LLMs produce random results that are less than useless (actually dangerous in many cases). Models designed for specific use cases can be very powerful. However, general AGI doesn't exist.
This sounds like OpenAI math.
October 16, 2025 at 7:59 PM
This sounds like OpenAI math.
Usually a trial with Vyvgart results in significant disease modification if it is caused by IgG. In some cases the disease resolves, in others anti-CD19 therapies can get remove the plasma cells producing the pathogenic autoantibody.
October 15, 2025 at 4:56 AM
Usually a trial with Vyvgart results in significant disease modification if it is caused by IgG. In some cases the disease resolves, in others anti-CD19 therapies can get remove the plasma cells producing the pathogenic autoantibody.
Most people with autoantibody driven disease are seronegative. Autoantibody tests really suck. Scientists are working on better ones, however it's a nontrivial task to make inexpensive high throughput assays that can accurately detect a wide array of pathogenic autoantibodies for any protein.
October 15, 2025 at 4:56 AM
Most people with autoantibody driven disease are seronegative. Autoantibody tests really suck. Scientists are working on better ones, however it's a nontrivial task to make inexpensive high throughput assays that can accurately detect a wide array of pathogenic autoantibodies for any protein.
After seeing a lot of patients in the neuroimmune axis disorders space (which includes many post-infectious illnesses) it's pretty easy to identify people who likely have autoantibody driven disease.
October 15, 2025 at 4:56 AM
After seeing a lot of patients in the neuroimmune axis disorders space (which includes many post-infectious illnesses) it's pretty easy to identify people who likely have autoantibody driven disease.
Off label just means that it is prescribed for a condition other than what it was FDA approved for. Vyvgart has been approved for a few autoimmune conditions, however it can be used for many more. Currently, if it's not covered by insurance it can be very expensive off label (~$100k per year).
October 15, 2025 at 4:56 AM
Off label just means that it is prescribed for a condition other than what it was FDA approved for. Vyvgart has been approved for a few autoimmune conditions, however it can be used for many more. Currently, if it's not covered by insurance it can be very expensive off label (~$100k per year).
The trial was poorly designed. However, Vyvgart worked really well for those with autoimmune phenotypes. We use it for a wide range of conditions off label (there are tons of conditions caused by IgG autoantibodies that are seronegative). The results are really impressive.
October 11, 2025 at 4:47 AM
The trial was poorly designed. However, Vyvgart worked really well for those with autoimmune phenotypes. We use it for a wide range of conditions off label (there are tons of conditions caused by IgG autoantibodies that are seronegative). The results are really impressive.