Marcus Kaiser
@connectomelab.bsky.social
Leader neuroinformatics.org.uk | Computational Psychiatry | Computational Neurology | Author of 'Changing Connectomes' https://mitpress.mit.edu/9780262044615/
https://www.dynamic-connectome.org/
https://www.dynamic-connectome.org/
Good to see so many Nottingham researchers at the @brainbox-init.bsky.social neuromodulation meeting!
A great meeting with ideas that we can bring home to our N3 neurotechnology centre
www.nottingham.ac.uk/news/centre-...
#tus #tms #tacs
A great meeting with ideas that we can bring home to our N3 neurotechnology centre
www.nottingham.ac.uk/news/centre-...
#tus #tms #tacs
September 26, 2025 at 2:40 PM
Good to see so many Nottingham researchers at the @brainbox-init.bsky.social neuromodulation meeting!
A great meeting with ideas that we can bring home to our N3 neurotechnology centre
www.nottingham.ac.uk/news/centre-...
#tus #tms #tacs
A great meeting with ideas that we can bring home to our N3 neurotechnology centre
www.nottingham.ac.uk/news/centre-...
#tus #tms #tacs
New: Zenbud ultrasound vagus nerve stimulation sham device cannot be distinguished from active device
www.mdpi.com/2076-3425/15...
We are now performing sham-controlled studies to observe cognitive and physiological effects...
#ultrasound #vagusnerve #neuromodulation
@mdpiopenaccess.bsky.social
www.mdpi.com/2076-3425/15...
We are now performing sham-controlled studies to observe cognitive and physiological effects...
#ultrasound #vagusnerve #neuromodulation
@mdpiopenaccess.bsky.social
September 13, 2025 at 2:30 PM
New: Zenbud ultrasound vagus nerve stimulation sham device cannot be distinguished from active device
www.mdpi.com/2076-3425/15...
We are now performing sham-controlled studies to observe cognitive and physiological effects...
#ultrasound #vagusnerve #neuromodulation
@mdpiopenaccess.bsky.social
www.mdpi.com/2076-3425/15...
We are now performing sham-controlled studies to observe cognitive and physiological effects...
#ultrasound #vagusnerve #neuromodulation
@mdpiopenaccess.bsky.social
Interesting to see that the UK is number 2 worldwide (after the USA) in terms of consumer neurotech employment, number of companies, and funding deals...
From Peter Schlecht's neurotech report at gppi.net/assets/Hensi...
From Peter Schlecht's neurotech report at gppi.net/assets/Hensi...
August 20, 2025 at 10:49 AM
Interesting to see that the UK is number 2 worldwide (after the USA) in terms of consumer neurotech employment, number of companies, and funding deals...
From Peter Schlecht's neurotech report at gppi.net/assets/Hensi...
From Peter Schlecht's neurotech report at gppi.net/assets/Hensi...
Great to see that the next generation of NeurGear's Zenbud ultrasound vagus nerve stimulator is now on sale!
First results show reductions in anxiety (neuro.jmir.org/2025/1/e69770 ).
Find out more about the device here:
zenbud.health/pages/anxiety
First results show reductions in anxiety (neuro.jmir.org/2025/1/e69770 ).
Find out more about the device here:
zenbud.health/pages/anxiety
August 18, 2025 at 1:54 PM
Great to see that the next generation of NeurGear's Zenbud ultrasound vagus nerve stimulator is now on sale!
First results show reductions in anxiety (neuro.jmir.org/2025/1/e69770 ).
Find out more about the device here:
zenbud.health/pages/anxiety
First results show reductions in anxiety (neuro.jmir.org/2025/1/e69770 ).
Find out more about the device here:
zenbud.health/pages/anxiety
Are you a registered healthcare professional searching for a PhD position?
Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'
midlandsmhndtp.ac.uk/uon-students...
Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'
midlandsmhndtp.ac.uk/uon-students...
July 3, 2025 at 12:36 PM
Are you a registered healthcare professional searching for a PhD position?
Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'
midlandsmhndtp.ac.uk/uon-students...
Using Zenbud #ultrasound #vagusnerve stimulation, the PhD position with me and Ben Marson is about 'Reducing pain reactivity for children in Emergency Departments'
midlandsmhndtp.ac.uk/uon-students...
We attended the London Great Exhibition Road festival over the weekend and 250+ people tried our Zenbud vagus nerve stimulation device!
One person suffering from anxiety/depression even came back on day 2 bringing a friend...
www.zenbud.health
#ultrasound #neuromodulation #vagusnerve
#ExRdFest
One person suffering from anxiety/depression even came back on day 2 bringing a friend...
www.zenbud.health
#ultrasound #neuromodulation #vagusnerve
#ExRdFest
June 9, 2025 at 10:18 AM
We attended the London Great Exhibition Road festival over the weekend and 250+ people tried our Zenbud vagus nerve stimulation device!
One person suffering from anxiety/depression even came back on day 2 bringing a friend...
www.zenbud.health
#ultrasound #neuromodulation #vagusnerve
#ExRdFest
One person suffering from anxiety/depression even came back on day 2 bringing a friend...
www.zenbud.health
#ultrasound #neuromodulation #vagusnerve
#ExRdFest
Our N3 Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics has officially launched at @uniofnottingham.bsky.social
#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social
www.nottingham.ac.uk/news/centre-...
#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social
www.nottingham.ac.uk/news/centre-...
May 9, 2025 at 9:55 AM
Our N3 Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics has officially launched at @uniofnottingham.bsky.social
#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social
www.nottingham.ac.uk/news/centre-...
#neuromodulation #imaging #focusedultrasound @fusfoundation.bsky.social
www.nottingham.ac.uk/news/centre-...
30 April deadline approaching!
Last chance to apply...
Last chance to apply...
April 25, 2025 at 7:45 PM
30 April deadline approaching!
Last chance to apply...
Last chance to apply...
Nice comparison of ultrasound and temporal interference stimulation in Table 3:
www.mrcbndu.ox.ac.uk/sites/defaul...
Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...
www.mrcbndu.ox.ac.uk/sites/defaul...
Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...
March 21, 2025 at 5:13 PM
Nice comparison of ultrasound and temporal interference stimulation in Table 3:
www.mrcbndu.ox.ac.uk/sites/defaul...
Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...
www.mrcbndu.ox.ac.uk/sites/defaul...
Ultrasound blinding option that is not mentioned is ventricle stimulation: doi.org/10.1016/j.br...
Conversely, brain metrics related to activity (fALFF) and signal homogeneity (ReHo) are altered for much longer: Going outside our time window of 100 minutes.
doi.org/10.1016/j.cr...
4/5
doi.org/10.1016/j.cr...
4/5
March 7, 2025 at 12:52 PM
Conversely, brain metrics related to activity (fALFF) and signal homogeneity (ReHo) are altered for much longer: Going outside our time window of 100 minutes.
doi.org/10.1016/j.cr...
4/5
doi.org/10.1016/j.cr...
4/5
We demonstrated that brain connectivity between the target and the rest of the brain was mostly changed for around 1h following the ultrasound
stimulation.
doi.org/10.1016/j.cr...
3/5
stimulation.
doi.org/10.1016/j.cr...
3/5
March 7, 2025 at 12:52 PM
We demonstrated that brain connectivity between the target and the rest of the brain was mostly changed for around 1h following the ultrasound
stimulation.
doi.org/10.1016/j.cr...
3/5
stimulation.
doi.org/10.1016/j.cr...
3/5
In this article, we present results about one animal who underwent around 50 MRIs, half of which followed ultrasound stimulation of the left anterior part of the hippocampus, a promising target since it is involved in so many brain dysfunctions.
doi.org/10.1016/j.cr...
2/5
doi.org/10.1016/j.cr...
2/5
March 7, 2025 at 12:52 PM
In this article, we present results about one animal who underwent around 50 MRIs, half of which followed ultrasound stimulation of the left anterior part of the hippocampus, a promising target since it is involved in so many brain dysfunctions.
doi.org/10.1016/j.cr...
2/5
doi.org/10.1016/j.cr...
2/5
I am very happy to share our latest work, led by C. Atkinson-Clement, C. Petkov, and M. Kaiser, on the temporal dynamics of brain changes following ultrasound stimulation in the rhesus monkey.
A huge thanks to all the team for making this work possible.
doi.org/10.1016/j.cr...
1/5
A huge thanks to all the team for making this work possible.
doi.org/10.1016/j.cr...
1/5
March 7, 2025 at 12:52 PM
I am very happy to share our latest work, led by C. Atkinson-Clement, C. Petkov, and M. Kaiser, on the temporal dynamics of brain changes following ultrasound stimulation in the rhesus monkey.
A huge thanks to all the team for making this work possible.
doi.org/10.1016/j.cr...
1/5
A huge thanks to all the team for making this work possible.
doi.org/10.1016/j.cr...
1/5
A chance to join our Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics by applying for a Newton postdoctoral fellowship from the Royal Society.
If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...
If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...
February 20, 2025 at 10:25 PM
A chance to join our Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics by applying for a Newton postdoctoral fellowship from the Royal Society.
If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...
If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...
Our survey article on how public and patients perceive interventions for brain and mental health, from implants and drugs to noninvasive focused ultrasound, is now published!
doi.org/10.1038/s415...
@fusfoundation.bsky.social @itrusst.bsky.social @brainbox-neuro.bsky.social
doi.org/10.1038/s415...
@fusfoundation.bsky.social @itrusst.bsky.social @brainbox-neuro.bsky.social
February 15, 2025 at 1:57 PM
Our survey article on how public and patients perceive interventions for brain and mental health, from implants and drugs to noninvasive focused ultrasound, is now published!
doi.org/10.1038/s415...
@fusfoundation.bsky.social @itrusst.bsky.social @brainbox-neuro.bsky.social
doi.org/10.1038/s415...
@fusfoundation.bsky.social @itrusst.bsky.social @brainbox-neuro.bsky.social
PhD position available for healthcare professionals on 'Mechanisms of action of ultrasound vagus nerve stimulation in generalised anxiety disorder'
midlandsmhndtp.ac.uk/project/2025...
midlandsmhndtp.ac.uk/project/2025...
January 13, 2025 at 1:49 PM
PhD position available for healthcare professionals on 'Mechanisms of action of ultrasound vagus nerve stimulation in generalised anxiety disorder'
midlandsmhndtp.ac.uk/project/2025...
midlandsmhndtp.ac.uk/project/2025...
Looks like I found the xmas tree option ;->
January 2, 2025 at 7:59 PM
Looks like I found the xmas tree option ;->
What parameters enhance or suppress brain function for online and offline focussed ultrasound stimulation?
Find out from our review:
'Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource'
doi.org/10.7554/eLif... @elife.bsky.social
Find out from our review:
'Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource'
doi.org/10.7554/eLif... @elife.bsky.social
December 7, 2024 at 9:47 AM
What parameters enhance or suppress brain function for online and offline focussed ultrasound stimulation?
Find out from our review:
'Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource'
doi.org/10.7554/eLif... @elife.bsky.social
Find out from our review:
'Neuromodulation with Ultrasound: Hypotheses on the Directionality of Effects and a Community Resource'
doi.org/10.7554/eLif... @elife.bsky.social
The article on ventricle ultrasound stimulation as a gold-standard control condition is now in press at Brain Stimulation.
Brilliant work led and initiated by my colleague Dr JeYoung Jung:
doi.org/10.1016/j.br...
@fusfoundation.bsky.social
Brilliant work led and initiated by my colleague Dr JeYoung Jung:
doi.org/10.1016/j.br...
@fusfoundation.bsky.social
December 6, 2024 at 2:42 PM
The article on ventricle ultrasound stimulation as a gold-standard control condition is now in press at Brain Stimulation.
Brilliant work led and initiated by my colleague Dr JeYoung Jung:
doi.org/10.1016/j.br...
@fusfoundation.bsky.social
Brilliant work led and initiated by my colleague Dr JeYoung Jung:
doi.org/10.1016/j.br...
@fusfoundation.bsky.social
Searching for a Christmas present for a #neuroscience, #psychology, or #NeuralNetworks researcher?
You may consider 'Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience' from @mitpress.bsky.social
mitpress.mit.edu/978026204461...
You may consider 'Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience' from @mitpress.bsky.social
mitpress.mit.edu/978026204461...
December 4, 2024 at 8:47 AM
Searching for a Christmas present for a #neuroscience, #psychology, or #NeuralNetworks researcher?
You may consider 'Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience' from @mitpress.bsky.social
mitpress.mit.edu/978026204461...
You may consider 'Changing Connectomes: Evolution, Development, and Dynamics in Network Neuroscience' from @mitpress.bsky.social
mitpress.mit.edu/978026204461...
This cognitive change in reduced reaction time was directly linked to biological change (rs-fMRI functional connectivity) and physical change (pressure change at target) as also confirmed by mediation analysis.
4/5
4/5
December 3, 2024 at 2:23 PM
This cognitive change in reduced reaction time was directly linked to biological change (rs-fMRI functional connectivity) and physical change (pressure change at target) as also confirmed by mediation analysis.
4/5
4/5
Testing around 1.5 hours after stimulation, reaction time was 8% faster for the IFC target in a stop-signal-task. Accuracy remained as high as before stimulation.
3/5
3/5
December 3, 2024 at 2:23 PM
Testing around 1.5 hours after stimulation, reaction time was 8% faster for the IFC target in a stop-signal-task. Accuracy remained as high as before stimulation.
3/5
3/5
By targeting either the inferior frontal cortex (IFC) or the thalamus (THAL), we observed distinct changes in fMRI up to 1h after the stimulation.
2/5
2/5
December 3, 2024 at 2:23 PM
By targeting either the inferior frontal cortex (IFC) or the thalamus (THAL), we observed distinct changes in fMRI up to 1h after the stimulation.
2/5
2/5
Our latest research is now online, unravelling the dynamic of ultrasound stimulation on the human brain!
How does functional connectivity change after #TUS and how is this linked to cognitive changes?
doi.org/10.1038/s415...
1/5
How does functional connectivity change after #TUS and how is this linked to cognitive changes?
doi.org/10.1038/s415...
1/5
December 3, 2024 at 2:23 PM
Our latest research is now online, unravelling the dynamic of ultrasound stimulation on the human brain!
How does functional connectivity change after #TUS and how is this linked to cognitive changes?
doi.org/10.1038/s415...
1/5
How does functional connectivity change after #TUS and how is this linked to cognitive changes?
doi.org/10.1038/s415...
1/5
Big batch of Zenbud noninvasive ultrasound vagus nerve stimulation devices have just arrived!
Don’t tell participants, but half are sham/control group devices :-)
#neurgear #neuromodulation #ultrasound
zenbud.health
Don’t tell participants, but half are sham/control group devices :-)
#neurgear #neuromodulation #ultrasound
zenbud.health
November 27, 2024 at 9:28 AM
Big batch of Zenbud noninvasive ultrasound vagus nerve stimulation devices have just arrived!
Don’t tell participants, but half are sham/control group devices :-)
#neurgear #neuromodulation #ultrasound
zenbud.health
Don’t tell participants, but half are sham/control group devices :-)
#neurgear #neuromodulation #ultrasound
zenbud.health