Colin Conine
@colinconine.bsky.social
Small RNA biologist at UPenn & CHOP
www.coninelab.com
Interested in small RNAs, germlines, inheritance, sports, and Shiba Inu’s
www.coninelab.com
Interested in small RNAs, germlines, inheritance, sports, and Shiba Inu’s
Reposted by Colin Conine
Check out related work by the Mendell lab (@mendell-lab.bsky.social) and the Xie lab: www.biorxiv.org/content/10.1..., www.biorxiv.org/content/10.1... (3/3)
Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503
Precise control of microRNA (miRNA) expression is critical during development. An important mechanism of miRNA regulation is target-directed microRNA degradation (TDMD), a pathway in which the binding...
www.biorxiv.org
November 7, 2025 at 6:33 PM
Check out related work by the Mendell lab (@mendell-lab.bsky.social) and the Xie lab: www.biorxiv.org/content/10.1..., www.biorxiv.org/content/10.1... (3/3)
Reposted by Colin Conine
And another interesting paper from Bonasio lab @upenn.edu www.biorxiv.org/content/10.1... "Pseudouridine selects RNAs for extracellular transport" noting among other things "..that MYL6 is a pU-binding protein required for secretion of RNAs." notable MYL6 is found in the Kossiakoff work as a csRBP!
Pseudouridine selects RNAs for extracellular transport
RNAs move through the extracellular space to transmit information between cells, including mammalian neurons, yet how specific RNAs are channeled into these extracellular routes is unknown. Using geno...
www.biorxiv.org
November 2, 2025 at 7:44 PM
And another interesting paper from Bonasio lab @upenn.edu www.biorxiv.org/content/10.1... "Pseudouridine selects RNAs for extracellular transport" noting among other things "..that MYL6 is a pU-binding protein required for secretion of RNAs." notable MYL6 is found in the Kossiakoff work as a csRBP!
Reposted by Colin Conine
Big thanks to all the speakers for their excellent talks: Adelheid Soubry @jamiehackett.bsky.social @nkotaja.bsky.social @romainbarres.bsky.social
@epitep.bsky.social
Anais Vitorino-Carvalho, kaylee Holleman, amrita Raja-ravi-shankar and Blair Schneider from the @colinconine.bsky.social lab
@epitep.bsky.social
Anais Vitorino-Carvalho, kaylee Holleman, amrita Raja-ravi-shankar and Blair Schneider from the @colinconine.bsky.social lab
October 20, 2025 at 4:08 PM
Big thanks to all the speakers for their excellent talks: Adelheid Soubry @jamiehackett.bsky.social @nkotaja.bsky.social @romainbarres.bsky.social
@epitep.bsky.social
Anais Vitorino-Carvalho, kaylee Holleman, amrita Raja-ravi-shankar and Blair Schneider from the @colinconine.bsky.social lab
@epitep.bsky.social
Anais Vitorino-Carvalho, kaylee Holleman, amrita Raja-ravi-shankar and Blair Schneider from the @colinconine.bsky.social lab