Claudia Villicaña
@clausvilli.bsky.social
Are you working with amazing viruses? Please check it out for this # SpecialIssue from #Horticulturae. Submissions are welcoming!!!
Emerging Strategies for Diagnosis and Management of Virus Diseases in Horticultural Crops: New Methods and Their Applications #mdpihorticulturae🌱
www.mdpi.com/si/243833
Emerging Strategies for Diagnosis and Management of Virus Diseases in Horticultural Crops: New Methods and Their Applications #mdpihorticulturae🌱
www.mdpi.com/si/243833
November 28, 2025 at 4:08 PM
Are you working with amazing viruses? Please check it out for this # SpecialIssue from #Horticulturae. Submissions are welcoming!!!
Emerging Strategies for Diagnosis and Management of Virus Diseases in Horticultural Crops: New Methods and Their Applications #mdpihorticulturae🌱
www.mdpi.com/si/243833
Emerging Strategies for Diagnosis and Management of Virus Diseases in Horticultural Crops: New Methods and Their Applications #mdpihorticulturae🌱
www.mdpi.com/si/243833
We are pleased to invite researchers, academics, and professionals to submit their original manuscripts to our Research Topic for the special issue "Pioneering Bioinoculant Methods for Sustainable Agriculture and Ecosystem Restoration" Please RT🧫🌲🌵
www.frontiersin.org/research-top...
www.frontiersin.org/research-top...
Frontiers | Pioneering Bioinoculant Methods for Sustainable Agriculture and Ecosystem Restoration
Agricultural sustainability is increasingly crucial as global demands on food production continue to rise. Traditional reliance on agrochemicals for enhancin...
www.frontiersin.org
November 28, 2025 at 3:41 PM
We are pleased to invite researchers, academics, and professionals to submit their original manuscripts to our Research Topic for the special issue "Pioneering Bioinoculant Methods for Sustainable Agriculture and Ecosystem Restoration" Please RT🧫🌲🌵
www.frontiersin.org/research-top...
www.frontiersin.org/research-top...
Reposted by Claudia Villicaña
Absolutely amazing method. Congrats!
November 21, 2025 at 10:19 AM
Absolutely amazing method. Congrats!
Reposted by Claudia Villicaña
Prophage induction drives soybean rhizobacterial community differentiation and nutrient cycling benefiting root development
[hypothesis: viral lysis increasing microbial activities/accelerating nutrient turnover▶️fast-growing populations stimulated]
-in #ISMEComms
academic.oup.com/ismecommun/a...
[hypothesis: viral lysis increasing microbial activities/accelerating nutrient turnover▶️fast-growing populations stimulated]
-in #ISMEComms
academic.oup.com/ismecommun/a...
Prophage induction drives soybean rhizobacterial community differentiation and nutrient cycling benefiting root development
Abstract. Bacteriophages, lytic or lysogenic, play critical roles in structuring different soil bacteriomes and driving their functionality. Lysogeny is fa
academic.oup.com
November 16, 2025 at 9:51 AM
Prophage induction drives soybean rhizobacterial community differentiation and nutrient cycling benefiting root development
[hypothesis: viral lysis increasing microbial activities/accelerating nutrient turnover▶️fast-growing populations stimulated]
-in #ISMEComms
academic.oup.com/ismecommun/a...
[hypothesis: viral lysis increasing microbial activities/accelerating nutrient turnover▶️fast-growing populations stimulated]
-in #ISMEComms
academic.oup.com/ismecommun/a...
Are you working with #plant #viruses? As a guest editor of this Special Issue, I invite all the potential collaborators to share their research about #biology, #management and #methods 🌱
www.mdpi.com/si/243833
www.mdpi.com/si/243833
www.mdpi.com
August 28, 2025 at 3:57 AM
Are you working with #plant #viruses? As a guest editor of this Special Issue, I invite all the potential collaborators to share their research about #biology, #management and #methods 🌱
www.mdpi.com/si/243833
www.mdpi.com/si/243833
Reposted by Claudia Villicaña
Preprint: We discovered phage proteins that sequester diverse immune signaling molecules, including cUMP, cCMP, and N7-cADPR
The first viral sponges to inhibit Pycsar and type IV Thoeris
Congrats to talented leading author Romi Hadary! Read her thread to learn more about our findings
The first viral sponges to inhibit Pycsar and type IV Thoeris
Congrats to talented leading author Romi Hadary! Read her thread to learn more about our findings
August 25, 2025 at 1:00 PM
Preprint: We discovered phage proteins that sequester diverse immune signaling molecules, including cUMP, cCMP, and N7-cADPR
The first viral sponges to inhibit Pycsar and type IV Thoeris
Congrats to talented leading author Romi Hadary! Read her thread to learn more about our findings
The first viral sponges to inhibit Pycsar and type IV Thoeris
Congrats to talented leading author Romi Hadary! Read her thread to learn more about our findings
Reposted by Claudia Villicaña
Great study indeed, demonstrating how functional amyloid mediate antiphage defense.
Probably many more systems out there working that way!
Probably many more systems out there working that way!
Very interesting work from Ibarlosa and colleagues regarding functional amyloid forming proteins in prokaryotic immunity.
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
www.nature.com/articles/s41...
Check out our News & Views summary of the work as well!
rdcu.be/eBHxh
Amyloids in bacterial antiphage defence
Nature Microbiology - Bacterial prions form amyloids in response to phage infection and induce cell death to prevent viral replication, similar to the processes in fungi and across the tree of life.
rdcu.be
August 21, 2025 at 3:24 PM
Great study indeed, demonstrating how functional amyloid mediate antiphage defense.
Probably many more systems out there working that way!
Probably many more systems out there working that way!
Reposted by Claudia Villicaña
#microsky #phage #phagesky
Presence of group II introns in phage genomes: academic.oup.com/nar/article/...
Presence of group II introns in phage genomes: academic.oup.com/nar/article/...
Presence of group II introns in phage genomes
Abstract. Although bacteriophage genomes are under strong selective pressure for high coding density, they are still frequently invaded by mobile genetic e
academic.oup.com
August 16, 2025 at 1:40 PM
#microsky #phage #phagesky
Presence of group II introns in phage genomes: academic.oup.com/nar/article/...
Presence of group II introns in phage genomes: academic.oup.com/nar/article/...
Reposted by Claudia Villicaña
Day 2 of #CSPB2025 kicks off with our first plenary! Dr. Dani Jones is sharing insights on using AI to drive smarter decision-making in agriculture 🤖🌿
Check out some of their relevant research: www.sciencedirect.com/science/arti...
Check out some of their relevant research: www.sciencedirect.com/science/arti...
Predicting sweetpotato traits using machine learning: Impact of environmental and agronomic factors on shape and size
Consumer preference in produce, defined by shape and size, heavily influences this market. Understanding the environmental and management factors that…
www.sciencedirect.com
August 11, 2025 at 12:12 PM
Day 2 of #CSPB2025 kicks off with our first plenary! Dr. Dani Jones is sharing insights on using AI to drive smarter decision-making in agriculture 🤖🌿
Check out some of their relevant research: www.sciencedirect.com/science/arti...
Check out some of their relevant research: www.sciencedirect.com/science/arti...
Reposted by Claudia Villicaña
our paper is online! rdcu.be/exXBX . Who would have thought that some #giantviruses not only have #histones, but even histone variants that make weird #nucleosomes (pdb 9CVT). Fantastic work from Ale Villalta and Chelsea Toner, with Hugo Bisio @molbiolgv.bsky.social and Chantal Abergel
Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures
Nature Communications - Melbournevirus encodes a conserved shorter H2B-H2A doublet variant. Here the authors report a cryo-EM structure of a nucleosome-like particle reconstituted with viral H4-H3...
rdcu.be
July 26, 2025 at 1:43 PM
our paper is online! rdcu.be/exXBX . Who would have thought that some #giantviruses not only have #histones, but even histone variants that make weird #nucleosomes (pdb 9CVT). Fantastic work from Ale Villalta and Chelsea Toner, with Hugo Bisio @molbiolgv.bsky.social and Chantal Abergel
Reposted by Claudia Villicaña
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
www.science.org
July 24, 2025 at 6:23 PM
🦠🧍♀️From bacterial to human immunity.
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity.
Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social
www.science.org/doi/10.1126/...
Reposted by Claudia Villicaña
Our paper on how integrons are biobanks of novel minimal defense systems is now out www.science.org/doi/10.1126/... Two main conclusions on this excellent work led by @eloilittner.bsky.social @baptistedarracq.bsky.social 1/n
May 9, 2025 at 1:07 PM
Our paper on how integrons are biobanks of novel minimal defense systems is now out www.science.org/doi/10.1126/... Two main conclusions on this excellent work led by @eloilittner.bsky.social @baptistedarracq.bsky.social 1/n
Reposted by Claudia Villicaña
#mRNA meets Tardigrades! Delivery of an mRNA encoding a protein from the famously tough animal can protect healthy tissue from damaging radiation. Very creative! #RNAsky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades - Nature Biomedical Engineering
Radiation-therapy-induced DNA damage in oral and rectal epithelial cells can be reduced via the nanoparticle-mediated local delivery of messenger RNA encoding for a damage-suppressor protein found in ...
www.nature.com
March 6, 2025 at 7:39 AM
#mRNA meets Tardigrades! Delivery of an mRNA encoding a protein from the famously tough animal can protect healthy tissue from damaging radiation. Very creative! #RNAsky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Claudia Villicaña
I am very grateful that the lab will be funded by NSERC for the next five years. This Discovery Grant will allow us to develop social evolution theory for viruses, including addressing many of the questions set out in our recent JEB review (doi.org/10.1111/jeb....).
#SocialViruses 🧪 🦠 #newPI
(1/2)
#SocialViruses 🧪 🦠 #newPI
(1/2)
Open questions in the social lives of viruses
Abstract. Social interactions among viruses occur whenever multiple viral genomes infect the same cells, hosts, or populations of hosts. Viral social inter
doi.org
April 3, 2025 at 9:01 PM
I am very grateful that the lab will be funded by NSERC for the next five years. This Discovery Grant will allow us to develop social evolution theory for viruses, including addressing many of the questions set out in our recent JEB review (doi.org/10.1111/jeb....).
#SocialViruses 🧪 🦠 #newPI
(1/2)
#SocialViruses 🧪 🦠 #newPI
(1/2)
Reposted by Claudia Villicaña
Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia.
DOI: 10.1093/nar/gkae1256
https://pubmed.ncbi.nlm.nih.gov/39727169/
DOI: 10.1093/nar/gkae1256
https://pubmed.ncbi.nlm.nih.gov/39727169/
Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia - PubMed
Coordinated actions of cells in microbial communities and multicellular organisms enable them to perform complex tasks otherwise difficult for single cells. This has inspired biological engineers to build cellular consortia for larger circuits with improved functionalities while implementing communi …
pubmed.ncbi.nlm.nih.gov
February 19, 2025 at 9:40 PM
Phage-mediated intercellular CRISPRi for biocomputation in bacterial consortia.
DOI: 10.1093/nar/gkae1256
https://pubmed.ncbi.nlm.nih.gov/39727169/
DOI: 10.1093/nar/gkae1256
https://pubmed.ncbi.nlm.nih.gov/39727169/
Reposted by Claudia Villicaña
Dot plots are an effective (if old school!) way to visualise the pairwise comparison of genomes.
For our recent pangenomics project (rdcu.be/d8PZ7), I wrote a small Python package to produce publication ready dot plots.
Check it out!
github.com/drboothtj/do...
pypi.org/project/dotp...
🧪🧬🦠
For our recent pangenomics project (rdcu.be/d8PZ7), I wrote a small Python package to produce publication ready dot plots.
Check it out!
github.com/drboothtj/do...
pypi.org/project/dotp...
🧪🧬🦠
February 6, 2025 at 9:42 AM
Dot plots are an effective (if old school!) way to visualise the pairwise comparison of genomes.
For our recent pangenomics project (rdcu.be/d8PZ7), I wrote a small Python package to produce publication ready dot plots.
Check it out!
github.com/drboothtj/do...
pypi.org/project/dotp...
🧪🧬🦠
For our recent pangenomics project (rdcu.be/d8PZ7), I wrote a small Python package to produce publication ready dot plots.
Check it out!
github.com/drboothtj/do...
pypi.org/project/dotp...
🧪🧬🦠
Reposted by Claudia Villicaña
On #InternationalDayofWomenandGirlsinScience let me remind you that we are NOWHERE NEAR parity. A few examples.
1. Women are credited less in science than men.
www.nature.com/articles/s41...
1. Women are credited less in science than men.
www.nature.com/articles/s41...
Women are credited less in science than men - Nature
The difference between the number of men and women listed as authors on scientific papers and inventors on patents is at least partly attributable to unacknowledged contributions by women scientists.
www.nature.com
February 11, 2025 at 4:02 PM
On #InternationalDayofWomenandGirlsinScience let me remind you that we are NOWHERE NEAR parity. A few examples.
1. Women are credited less in science than men.
www.nature.com/articles/s41...
1. Women are credited less in science than men.
www.nature.com/articles/s41...
Reposted by Claudia Villicaña
Another newly discovered mechanism of bacteria inhibiting competitors - increasing their sensitivity to phages - fascinating
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Streptomyces secretes a siderophore that sensitizes competitor bacteria to phage infection - Nature Microbiology
A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.
www.nature.com
January 9, 2025 at 6:56 AM
Another newly discovered mechanism of bacteria inhibiting competitors - increasing their sensitivity to phages - fascinating
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Claudia Villicaña
My main PhD work is now out!
We find that choice of antibiotic and the level of (sub-inhibitory) dose is important for combining with phages. Good combinations reduce resistance evolution and simple antibiotic susceptibility experiments can help us choose
Co-authors not on bsky, brief thread below
We find that choice of antibiotic and the level of (sub-inhibitory) dose is important for combining with phages. Good combinations reduce resistance evolution and simple antibiotic susceptibility experiments can help us choose
Co-authors not on bsky, brief thread below
Gram-neg bacteria can resist #phages by modifying their LPS, also affecting #antibiotic susceptibility. @lavishaparab.bsky.social &co show that antibiotic concentrations influence evolution of E. coli phage resistance, leading to enhanced phage-antibiotic synergy 🧪 @plosbiology.org plos.io/4hPmO0X
January 27, 2025 at 8:42 PM
My main PhD work is now out!
We find that choice of antibiotic and the level of (sub-inhibitory) dose is important for combining with phages. Good combinations reduce resistance evolution and simple antibiotic susceptibility experiments can help us choose
Co-authors not on bsky, brief thread below
We find that choice of antibiotic and the level of (sub-inhibitory) dose is important for combining with phages. Good combinations reduce resistance evolution and simple antibiotic susceptibility experiments can help us choose
Co-authors not on bsky, brief thread below