Chrysante Iliakis
@chrysante-ili.bsky.social
Former PhD student, now postdoc in the lab of Andreas Wack @crick.ac.uk
Studying alveolar macrophage phenotype and function after lung infection
🔬🇬🇷🇩🇪
Studying alveolar macrophage phenotype and function after lung infection
🔬🇬🇷🇩🇪
Reposted by Chrysante Iliakis
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
Hematopoietic aging drives lung fibrosis and profibrotic macrophage influx, stalling their maturation via reduced Treg-derived IL-10.
www.science.org
March 28, 2025 at 7:10 PM
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
Reposted by Chrysante Iliakis
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
Reposted by Chrysante Iliakis
Review
Tissue-resident immune cells: from defining characteristics to roles in diseases
www.nature.com/articles/s41...
Tissue-resident immune cells: from defining characteristics to roles in diseases
www.nature.com/articles/s41...
January 19, 2025 at 3:18 AM
Review
Tissue-resident immune cells: from defining characteristics to roles in diseases
www.nature.com/articles/s41...
Tissue-resident immune cells: from defining characteristics to roles in diseases
www.nature.com/articles/s41...
Reposted by Chrysante Iliakis
#WeekendRead! Ahn, Arthur &co show @CellHost&Microbe that pathogenic E. coli produce a metallophore that sequesters zinc in macrophages, stabilizing HIF1a & driving fibrosis in #IBD mouse models and Crohn Disease patients! www.sciencedirect.com/science/arti...
Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
Inflammatory bowel disease (IBD)-associated fibrosis causes significant morbidity. Mechanisms are poorly understood but implicate the microbiota, espe…
www.sciencedirect.com
January 11, 2025 at 3:41 PM
#WeekendRead! Ahn, Arthur &co show @CellHost&Microbe that pathogenic E. coli produce a metallophore that sequesters zinc in macrophages, stabilizing HIF1a & driving fibrosis in #IBD mouse models and Crohn Disease patients! www.sciencedirect.com/science/arti...
Reposted by Chrysante Iliakis
How do NKT cells control epithelial cell biology and function in the small intestine ?
Thrilled to share my PhD work investigating the cytokine driven crosstalk between NKT cells and epithelial cells in the gut @barrallab.bsky.social
Thrilled to share my PhD work investigating the cytokine driven crosstalk between NKT cells and epithelial cells in the gut @barrallab.bsky.social
Our first 🦋 post! Very happy to share our latest paper just out in Cell Reports, exploring the crosstalk between immune and epithelial cells in the gut. Check it out!
@vivianlilab.bsky.social @kingscollegelondon.bsky.social
www.cell.com/cell-reports...
@vivianlilab.bsky.social @kingscollegelondon.bsky.social
www.cell.com/cell-reports...
IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells
The crosstalk between immune and epithelial cells is vital to maintain intestinal
homeostasis. Lebrusant-Fernandez et al. identify NKT cells in the small intestine
as key regulators of epithelial biol...
www.cell.com
November 24, 2024 at 3:42 PM
How do NKT cells control epithelial cell biology and function in the small intestine ?
Thrilled to share my PhD work investigating the cytokine driven crosstalk between NKT cells and epithelial cells in the gut @barrallab.bsky.social
Thrilled to share my PhD work investigating the cytokine driven crosstalk between NKT cells and epithelial cells in the gut @barrallab.bsky.social