Anastasia Christakou 💙
@christakou.bsky.social
Professor of Neuroscience 👩🎓
own views 🐙 anastasia.christakou.org
https://orcid.org/0000-0002-4267-3436
children's welfare | science | 🧠 brains & their people
own views 🐙 anastasia.christakou.org
https://orcid.org/0000-0002-4267-3436
children's welfare | science | 🧠 brains & their people
Definitely legitimate. The wise people of @rorinstitute.bsky.social are involved.
November 27, 2025 at 6:46 PM
Definitely legitimate. The wise people of @rorinstitute.bsky.social are involved.
Obviously I loved it.
They played Like Spinning Plates!
I have opinions of course, but they're boring (I told the BFF you asked and he just said 'poor guy...' 😅).
In all honesty, I'm so far gone that they could come out, slap me across the face with a wet fish and leave, and I would still love it.
They played Like Spinning Plates!
I have opinions of course, but they're boring (I told the BFF you asked and he just said 'poor guy...' 😅).
In all honesty, I'm so far gone that they could come out, slap me across the face with a wet fish and leave, and I would still love it.
a man with a beard is smiling and holding his hand to his chin on a stage .
ALT: a man with a beard is smiling and holding his hand to his chin on a stage .
media.tenor.com
November 26, 2025 at 6:31 PM
Obviously I loved it.
They played Like Spinning Plates!
I have opinions of course, but they're boring (I told the BFF you asked and he just said 'poor guy...' 😅).
In all honesty, I'm so far gone that they could come out, slap me across the face with a wet fish and leave, and I would still love it.
They played Like Spinning Plates!
I have opinions of course, but they're boring (I told the BFF you asked and he just said 'poor guy...' 😅).
In all honesty, I'm so far gone that they could come out, slap me across the face with a wet fish and leave, and I would still love it.
It's been soooo long 😭
a man in a red sweater is talking to another man in a black jacket .
ALT: a man in a red sweater is talking to another man in a black jacket .
media.tenor.com
November 24, 2025 at 2:27 PM
It's been soooo long 😭
Nooooo! I'm lying, I want to know everything! 😭
November 24, 2025 at 2:25 PM
Nooooo! I'm lying, I want to know everything! 😭
No, please, I don't want to know, I can barely concentrate on anything.
November 24, 2025 at 2:24 PM
No, please, I don't want to know, I can barely concentrate on anything.
I agree with this 'sentiment' - core to how I think about cognitive substrates (as self-sensitive processes).
Although, having grappled with the transformations of mixed autoregulatory feedback (eg receptor up-/down-regulation etc.), I would hesitate to state it as plainly and eloquently as that.
Although, having grappled with the transformations of mixed autoregulatory feedback (eg receptor up-/down-regulation etc.), I would hesitate to state it as plainly and eloquently as that.
November 24, 2025 at 12:26 PM
I agree with this 'sentiment' - core to how I think about cognitive substrates (as self-sensitive processes).
Although, having grappled with the transformations of mixed autoregulatory feedback (eg receptor up-/down-regulation etc.), I would hesitate to state it as plainly and eloquently as that.
Although, having grappled with the transformations of mixed autoregulatory feedback (eg receptor up-/down-regulation etc.), I would hesitate to state it as plainly and eloquently as that.
..."the tools [that are imported to] neuroscience [through physics and engineering]"...
Therefore the worry may be less about vetting the tools themselves, and more about the inferences drawn from their application.
Therefore the worry may be less about vetting the tools themselves, and more about the inferences drawn from their application.
November 24, 2025 at 10:10 AM
..."the tools [that are imported to] neuroscience [through physics and engineering]"...
Therefore the worry may be less about vetting the tools themselves, and more about the inferences drawn from their application.
Therefore the worry may be less about vetting the tools themselves, and more about the inferences drawn from their application.
Would you go as far as to agree that dimensionality (in biological information processing systems) is a property of the receiver, not of the data or of the computation?
November 24, 2025 at 9:49 AM
Would you go as far as to agree that dimensionality (in biological information processing systems) is a property of the receiver, not of the data or of the computation?
This is someone who saw an opportunity and took it 👏
November 21, 2025 at 4:01 PM
This is someone who saw an opportunity and took it 👏
“inspired by the concept of a piece of cloth" 🤦
November 19, 2025 at 1:59 PM
“inspired by the concept of a piece of cloth" 🤦
Ok, this is about falsifying a hypothesis, the only thing an experiment can do, not about falsifying a theory.
Theories can be stated in non-falsifiable terms and still be useful/correct, and are in any case too broad for a single dataset to handle (something that Lakatos explicitly acknowledges).
Theories can be stated in non-falsifiable terms and still be useful/correct, and are in any case too broad for a single dataset to handle (something that Lakatos explicitly acknowledges).
November 18, 2025 at 4:04 PM
Ok, this is about falsifying a hypothesis, the only thing an experiment can do, not about falsifying a theory.
Theories can be stated in non-falsifiable terms and still be useful/correct, and are in any case too broad for a single dataset to handle (something that Lakatos explicitly acknowledges).
Theories can be stated in non-falsifiable terms and still be useful/correct, and are in any case too broad for a single dataset to handle (something that Lakatos explicitly acknowledges).
Falsification is robust to inductive bias tho'; what is more robust than that?
November 18, 2025 at 10:58 AM
Falsification is robust to inductive bias tho'; what is more robust than that?
It seems the core difference in our 'epistemologies' then may be optimising for efficient versus robust inference.
Perhaps we can agree that sometimes we can get away with collecting data for the former, but other times we simply need to know for sure.
Perhaps we can agree that sometimes we can get away with collecting data for the former, but other times we simply need to know for sure.
November 18, 2025 at 10:46 AM
It seems the core difference in our 'epistemologies' then may be optimising for efficient versus robust inference.
Perhaps we can agree that sometimes we can get away with collecting data for the former, but other times we simply need to know for sure.
Perhaps we can agree that sometimes we can get away with collecting data for the former, but other times we simply need to know for sure.
I see. This is alien to me.
For what should we optimise experiments if not to test a hypothesis?
For what should we optimise experiments if not to test a hypothesis?
November 18, 2025 at 10:21 AM
I see. This is alien to me.
For what should we optimise experiments if not to test a hypothesis?
For what should we optimise experiments if not to test a hypothesis?
This also implies that there is no dataset that will 'make sense of the brain', which means we agree, but for different reasons and to a different conclusion.
November 18, 2025 at 8:48 AM
This also implies that there is no dataset that will 'make sense of the brain', which means we agree, but for different reasons and to a different conclusion.
Good experimental data is not very pluralistic (i.e. not amenable to much modelling, however creative) precisely because the experiment should have been designed with a specific question in mind.
November 18, 2025 at 8:48 AM
Good experimental data is not very pluralistic (i.e. not amenable to much modelling, however creative) precisely because the experiment should have been designed with a specific question in mind.
This may be an indication of us coming from different traditions. In my mind you acquire data to answer a question. It may be that you don't get a complete answer, but at least you'll know what the next question should be.
November 18, 2025 at 8:48 AM
This may be an indication of us coming from different traditions. In my mind you acquire data to answer a question. It may be that you don't get a complete answer, but at least you'll know what the next question should be.
This implies that the data is collected for its own sake and not in the process of theory testing. But collecting data is at the core of sense-making in experimental science.
November 17, 2025 at 7:30 PM
This implies that the data is collected for its own sake and not in the process of theory testing. But collecting data is at the core of sense-making in experimental science.
I just spotted the 5th one! 🤩
November 17, 2025 at 9:28 AM
I just spotted the 5th one! 🤩
One cow short of a '00s @radiohead.bsky.social press photo...
November 17, 2025 at 9:27 AM
One cow short of a '00s @radiohead.bsky.social press photo...
Yes, I think so. A difficult thing to practice and communicate in 2025.
November 17, 2025 at 9:19 AM
Yes, I think so. A difficult thing to practice and communicate in 2025.