Cheng Lab
@chenglab.bsky.social
Eye Lens Cell and Molecular Biology, Indiana University School of Optometry
Studying age-related lens pathologies
Trained at Berkeley BioEngineering & Scripps Research
Studying age-related lens pathologies
Trained at Berkeley BioEngineering & Scripps Research
Congrats Gryffin! His first First Author article challenges the belief that increased lens size with age, particularly of the nucleus, is the primary cause of presbyopia. It further describes roles that Eph-ephrin signaling has in lens development. #VisionScience Read here doi.org/10.3389/foph...
December 2, 2025 at 2:05 PM
Congrats Gryffin! His first First Author article challenges the belief that increased lens size with age, particularly of the nucleus, is the primary cause of presbyopia. It further describes roles that Eph-ephrin signaling has in lens development. #VisionScience Read here doi.org/10.3389/foph...
Not too long ago, Yuka came to visit our lab and collaborated with some projects! We're grateful for the visit and look forward to her next one!
November 21, 2025 at 3:40 PM
Not too long ago, Yuka came to visit our lab and collaborated with some projects! We're grateful for the visit and look forward to her next one!
Our new protocol shows how to cleanly isolate RNA from mouse lens epithelium and bulk fiber cell mass for qPCR. Prior, limited amounts of RNA could be extracted from the monolayer of epi. cells, thus sample pooling. Now, we can get better in-depth analysis, no pooling. app.jove.com/t/69079/rna-...
November 18, 2025 at 6:23 PM
Our new protocol shows how to cleanly isolate RNA from mouse lens epithelium and bulk fiber cell mass for qPCR. Prior, limited amounts of RNA could be extracted from the monolayer of epi. cells, thus sample pooling. Now, we can get better in-depth analysis, no pooling. app.jove.com/t/69079/rna-...
Early in October, Dr. Catherine Cheng presented Gryffin's masters thesis project about age-related changes in ocular lens biomechanics and morphometrics in regards to implications for presbyopia. It was great time sharing knowledge at the 2025 AOSA Midwestern Regional Conference!
November 17, 2025 at 4:46 PM
Early in October, Dr. Catherine Cheng presented Gryffin's masters thesis project about age-related changes in ocular lens biomechanics and morphometrics in regards to implications for presbyopia. It was great time sharing knowledge at the 2025 AOSA Midwestern Regional Conference!
As Halloween approaches, the lab celebrated Gryffin's birthday! Yet another spooky event for the month of October. Happy Birthday Gryffin!
October 20, 2025 at 3:10 PM
As Halloween approaches, the lab celebrated Gryffin's birthday! Yet another spooky event for the month of October. Happy Birthday Gryffin!
We wish you all the best Dr. Hsuan-Yeh Pan! We've known Hsuan-Yeh since before he earned his doctorate and have enjoyed funny conversations with him as lab neighbors. We hope to see you at some conferences soon!
August 26, 2025 at 12:36 PM
We wish you all the best Dr. Hsuan-Yeh Pan! We've known Hsuan-Yeh since before he earned his doctorate and have enjoyed funny conversations with him as lab neighbors. We hope to see you at some conferences soon!
This year's HVRS went great! Well done presenting your talks Gryffin and Isaiah! Also, we really enjoyed learning about the research happening from other institutes! We are eager to hear research updates at next year's symposium!
August 20, 2025 at 7:15 PM
This year's HVRS went great! Well done presenting your talks Gryffin and Isaiah! Also, we really enjoyed learning about the research happening from other institutes! We are eager to hear research updates at next year's symposium!
After 2.5 years, @peterhuynh.bsky.social has decided to explore new career opportunities. Thanks for sharing your insight & experience. You've significantly improved our ability to analyze & refine vast, complex lens data. We'll miss your humor & diligence and wish you the best in your explorations!
August 18, 2025 at 6:46 PM
After 2.5 years, @peterhuynh.bsky.social has decided to explore new career opportunities. Thanks for sharing your insight & experience. You've significantly improved our ability to analyze & refine vast, complex lens data. We'll miss your humor & diligence and wish you the best in your explorations!
This past month, the lab went to waft Wally for the second time! He was not shy about sharing the reason why he's classified as a corpse flower! Looking forward to scenting you again soon Wally!
July 16, 2025 at 2:10 PM
This past month, the lab went to waft Wally for the second time! He was not shy about sharing the reason why he's classified as a corpse flower! Looking forward to scenting you again soon Wally!
The lab recently celebrated Jenna and Michael's birthdays by the vine at Butler Winery! It was a great time eating, drinking, and playing games! Happy Birthday you two!
July 14, 2025 at 5:39 PM
The lab recently celebrated Jenna and Michael's birthdays by the vine at Butler Winery! It was a great time eating, drinking, and playing games! Happy Birthday you two!
The article collection where Dr. Barbara Pierscionek & Dr. Cheng were co-editors was published in May! Together, they wrote an editorial highlighting 7 original research & 2 reviews on lens & cataract research. eBook of the entire collection is available below! tinyurl.com/2b3b2nc8
#VisionScience
#VisionScience
July 9, 2025 at 1:04 PM
The article collection where Dr. Barbara Pierscionek & Dr. Cheng were co-editors was published in May! Together, they wrote an editorial highlighting 7 original research & 2 reviews on lens & cataract research. eBook of the entire collection is available below! tinyurl.com/2b3b2nc8
#VisionScience
#VisionScience
In March, the School of Optometry volunteered to run some #VisionScience activities for the young visionaries at GEMS 2025! As always, the kids' excitement and curiosity were off the charts, making it a great time! We are looking forward to continuing sharing our knowledge about the eye in 2026!
July 7, 2025 at 12:36 PM
In March, the School of Optometry volunteered to run some #VisionScience activities for the young visionaries at GEMS 2025! As always, the kids' excitement and curiosity were off the charts, making it a great time! We are looking forward to continuing sharing our knowledge about the eye in 2026!
The lab celebrated Isaiah's birthday a few months ago, but who doesn't appreciate a belated birthday post? Happy Birthday Isaiah!
July 2, 2025 at 12:36 PM
The lab celebrated Isaiah's birthday a few months ago, but who doesn't appreciate a belated birthday post? Happy Birthday Isaiah!
We had a great visit from Dr. Yuka Okada in March! Enjoy a photo from when we took a break from collaborating! See you again soon, Dr. Okada!
June 27, 2025 at 2:17 PM
We had a great visit from Dr. Yuka Okada in March! Enjoy a photo from when we took a break from collaborating! See you again soon, Dr. Okada!
Gryffin presented his lab work at Oxyopia on March 28th. Titled: "Eph-ephrin signaling is required for normal lens growth, shape, and nucleus stiffness". His work examined mechanical properties of the lens. He did a great job presenting his findings with his peers!
June 24, 2025 at 1:30 PM
Gryffin presented his lab work at Oxyopia on March 28th. Titled: "Eph-ephrin signaling is required for normal lens growth, shape, and nucleus stiffness". His work examined mechanical properties of the lens. He did a great job presenting his findings with his peers!
@peterhuynh.bsky.social presented his research at IUSO's Oxyopia on March 14. Titled: "Spatial-Temporal Topography of Ephs and Ephrins in the Lens" it covered the work he's done to narrow down potential binding partners for EphA2 or ephrin-A5 via qPCR. Excellent job presenting your challenging work!
June 23, 2025 at 7:09 PM
@peterhuynh.bsky.social presented his research at IUSO's Oxyopia on March 14. Titled: "Spatial-Temporal Topography of Ephs and Ephrins in the Lens" it covered the work he's done to narrow down potential binding partners for EphA2 or ephrin-A5 via qPCR. Excellent job presenting your challenging work!
At the end of May, the lab was able to gather and celebrate Dr. Cheng's & Arya's birthdays, Jackson's optometry school graduation, Jenna's vision science M.S. conferment, and Gryffin's graduation with a B.S. in optometry! Congratulations everyone! The lab would not be where it is without you all!
June 18, 2025 at 5:19 PM
At the end of May, the lab was able to gather and celebrate Dr. Cheng's & Arya's birthdays, Jackson's optometry school graduation, Jenna's vision science M.S. conferment, and Gryffin's graduation with a B.S. in optometry! Congratulations everyone! The lab would not be where it is without you all!
In addition to Gryffin and Jackson earning degrees, Jenna was awarded her Masters of Science in Vision Science, based on the hard work that she has put in with the lab! Her thesis work can be found here: www.aging-us.com/article/2061.... Congratulations Jenna!
June 17, 2025 at 7:28 PM
In addition to Gryffin and Jackson earning degrees, Jenna was awarded her Masters of Science in Vision Science, based on the hard work that she has put in with the lab! Her thesis work can be found here: www.aging-us.com/article/2061.... Congratulations Jenna!
Gryffin was admitted early to the Indiana University School of Optometry Program in place of finishing senior year of undergrad. Upon completion of his second year at IUSO, he received his Bachelor of Science in Optometry. Congratulations Gryffin!
June 13, 2025 at 1:03 PM
Gryffin was admitted early to the Indiana University School of Optometry Program in place of finishing senior year of undergrad. Upon completion of his second year at IUSO, he received his Bachelor of Science in Optometry. Congratulations Gryffin!
Congratulations to Jackson! He graduated at the beginning of May with his Doctor of Optometry degree! We wish you all the best and thank you for the laughs the past few years!
June 12, 2025 at 2:32 PM
Congratulations to Jackson! He graduated at the beginning of May with his Doctor of Optometry degree! We wish you all the best and thank you for the laughs the past few years!
Congratulations to Gryffin on receiving his white coat at the end of March! With his white coat, Gryffin has been spending much of his time over in the clinic applying the knowledge and skills he's gained in the past two years! Congratulations again Gryffin!
June 11, 2025 at 2:29 PM
Congratulations to Gryffin on receiving his white coat at the end of March! With his white coat, Gryffin has been spending much of his time over in the clinic applying the knowledge and skills he's gained in the past two years! Congratulations again Gryffin!
Throw back to when the lab was getting some field experience examining how animals use their lens at the Indianapolis Zoo!!
March 10, 2025 at 8:11 PM
Throw back to when the lab was getting some field experience examining how animals use their lens at the Indianapolis Zoo!!
Waking up from the food coma to finally give thanks to everyone (past and present) for making the lab a great place to hang out!
December 10, 2024 at 4:07 PM
Waking up from the food coma to finally give thanks to everyone (past and present) for making the lab a great place to hang out!
Congrats Jenna, Michael, Jackson, and Isaiah on the new article; Jenna and Isaiah's first with the lab! Of note, our data is the first showing that non-canonical EphA2 signaling is active in normal lenses, and our results suggest a physiological function. t.ly/7i8Ve #VisionScience #AcademicSky
November 5, 2024 at 8:07 PM
Congrats Jenna, Michael, Jackson, and Isaiah on the new article; Jenna and Isaiah's first with the lab! Of note, our data is the first showing that non-canonical EphA2 signaling is active in normal lenses, and our results suggest a physiological function. t.ly/7i8Ve #VisionScience #AcademicSky
Happy Birthday to Gryffin! Glad we were able to fit in a birthday lunch amidst all the work and study!
October 25, 2024 at 12:53 PM
Happy Birthday to Gryffin! Glad we were able to fit in a birthday lunch amidst all the work and study!