Celine Grenier, PhD
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celinegrenier-phd.bsky.social
Celine Grenier, PhD
@celinegrenier-phd.bsky.social
Postdoc in the Lennon lab at the University of Manchester. Study kidney disease in zebrafish and mice. Love playing video games and reading Fantasy and Sci-Fi books during my free time.
Reposted by Celine Grenier, PhD
We'll always have matrix... Happy holidays to all our members and collaborators.
December 20, 2024 at 10:06 AM
Reposted by Celine Grenier, PhD
Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship https://www.biorxiv.org/content/10.1101/2024.11.19.624265v1
Golgins support extracellular matrix secretion by collectively maintaining the Golgi structure-function relationship https://www.biorxiv.org/content/10.1101/2024.11.19.624265v1
The secretion of extracellular matrix (ECM) proteins is vital to the maintenance of tissue health. O
www.biorxiv.org
November 21, 2024 at 11:30 AM
Reposted by Celine Grenier, PhD

Delighted to share our latest paper:

"The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response"

Expertly led by Rebecca Preston & in collaboration with clock superstar Qing Jun Meng

pubmed.ncbi.nlm.nih.gov/39515644/

Key findings 👇👇
November 21, 2024 at 3:39 PM
Reposted by Celine Grenier, PhD
TIL EZRC resources 🤗
November 21, 2024 at 6:17 AM
Reposted by Celine Grenier, PhD
For our 🦋: Tomorrow 3pm CET, grab your hot cocoa (ok coffee, let's be real) & let's get cozier with a talk by the amazing S. Ricard-Blum. All about computational biology, ECM protein interactions & the new vers of MatrixDB! Chair: @merrylabnotts.bsky.social Zoom link: t.co/mFDZASKYFH
November 19, 2024 at 4:31 PM
Reposted by Celine Grenier, PhD
Welcome to Bsky @themeshwork.bsky.social - the platform for #ECMatrix lovers with the aim to connect Early Career Researchers around the world 🌍 Completely free to join!
November 19, 2024 at 10:40 AM
Reposted by Celine Grenier, PhD
Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib
November 17, 2024 at 4:04 PM
Reposted by Celine Grenier, PhD
Was great fun to talk to @nephrosparks.bsky.social about digenic Alport syndrome. Give it a listen!
New Episode of ASN Kidney Translation with @nephrosparks.bsky.social

Genetic Testing in Nephrology: Topics include genetic testing in CKD, MUC1 ADTKD screening, and digenic Alport syndrome insights

podcasts.apple.com/us/podcast/g...
November 17, 2024 at 3:49 PM
Reposted by Celine Grenier, PhD
"The antibodies don’t work!"

We, like many labs, have faced issues with bad antibodies cell.com/cell-stem-ce...

Great to see that some are tackling this problem head-on!

Read more about their solutions:
www.nature.com/articles/d41...

#ImmunoSky #Metaresearch #Openscience
The antibodies don’t work! The race to rid labs of molecules that ruin experiments
Poorly performing antibodies have plagued biomedical sciences for decades. Several fresh initiatives hope to change this.
www.nature.com
November 6, 2024 at 11:46 AM
Reposted by Celine Grenier, PhD
Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation. https://www.biorxiv.org/content/10.1101/2024.11.15.623782v1
Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation. https://www.biorxiv.org/content/10.1101/2024.11.15.623782v1
The extracellular matrix (ECM) forms the scaffold in which cells reside and interact. The compositio
www.biorxiv.org
November 18, 2024 at 2:16 AM
Reposted by Celine Grenier, PhD
Our spotlight on collagen- formation, function & role in kidney disease is out now!

A wonderful collaboration with Moumita Barua & Vanessa De Gregorio

#ECMatrix
#Nephro

Cell-Matrix Centre
@fbmh-uom.bsky.social
@uoft.bsky.social

www.nature.com/articles/s41...
Collagen formation, function and role in kidney disease - Nature Reviews Nephrology
Collagens are ubiquitously expressed and have been linked to a broad spectrum of disorders. Here, the authors discuss collagen subtypes and provide a summary of collagen disorders, fibrotic process an...
www.nature.com
November 18, 2024 at 6:28 AM
Integrin alpha1 beta1 promotes interstitial fibrosis in a mouse model of polycystic kidney disease www.biorxiv.org/content/10.1...
Integrin alpha1 beta1 promotes interstitial fibrosis in a mouse model of polycystic kidney disease
Fibrosis is the cause of end-stage kidney failure in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD). The molecular and cellular mechanisms involved in fibrosis are complex and anti...
www.biorxiv.org
November 17, 2024 at 10:41 PM
Reposted by Celine Grenier, PhD
Let's gather the #ECMatrix community!!
go.bsky.app/47xREVJ
November 16, 2024 at 10:31 AM
Reposted by Celine Grenier, PhD
Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration https://www.biorxiv.org/content/10.1101/2024.11.15.623835v1
Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration https://www.biorxiv.org/content/10.1101/2024.11.15.623835v1
Understanding how mechanical stimulation from exercise influences cellular responses during tissue r
www.biorxiv.org
November 17, 2024 at 2:31 PM