cedric-blanpain.bsky.social
@cedric-blanpain.bsky.social
So happy to see that Nature Cancer had chosen our picture as the cover of their September issue together with the publication of our paper on stem cell plasticity during prostate tumor initiation. Congratulations to @ChenJiang919 and @yura__song
🍂Our September issue is OUT NOW!

Featuring, among others:
- A Perspective on #drugconjugates
- #immunotherapy studies
- research on GBM invasion
- method for #singlecell analyses of #CTCs

🔗 www.nature.com/natcancer/vo...
September 28, 2025 at 4:51 PM
I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprograming of prostate tumor initiating cells published in
@NatureCancer
. Congrats
@ChenJiang919
and
@yura__song
, the first authors,
www.nature.com/articles/s43...
Innate immunity and the NF-κB pathway control prostate stem cell plasticity, reprogramming and tumor initiation - Nature Cancer
Blanpain and colleagues delineate lineage reprogramming following PTEN deletion in different prostate cancer-originating cells, demonstrating that in basal cells the NF-κB pathway and innate immunity ...
www.nature.com
June 23, 2025 at 1:23 PM
Reposted
Leaving our #EACR congress in Lisbon appreciating both the incredible science and the amazing community we have - with many wonderful friends!

#EACR2025 🤩

@helloeacr.bsky.social
@adaptmet.bsky.social
@msmelanoma.bsky.social
@arkaitzcarracedo.bsky.social
@svanharanta.bsky.social
June 19, 2025 at 1:41 PM
Reposted
Out @nature.com: Clonal tracing with somatic epimutations

🧬 Single cell methylome encodes cell state & clonal identity

🔨 EPI-Clone reads out both (+mutations, +RNA) at scale

🩸 Clonal expansions of HSCs are universal from age 50, not driven by CH mutations

doi.org/10.1038/s415...
🧵
Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature
The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing th...
doi.org
May 21, 2025 at 3:44 PM