Carolina Cabalín
@carolinacabalin.bsky.social
🇨🇱👩🔬 PhD in Medical Sciences - Skin immunology | Postdoc in T cells & Cancer immunology at Weill Cornell Medicine 🗽| Pew Latin American Fellow 2024 | Biochemist | 🌍🚀🏐🐶🐱👩🍳🍀🌵
Pinned
This week has been full of wonderful scientific news ✨👩🏼🔬
🫨🫨
Escherichia coli-induced gut IL-33 release inhibits lung type 2 allergic responses https://www.biorxiv.org/content/10.1101/2025.11.07.687219v1
November 10, 2025 at 8:59 PM
🫨🫨
Reposted by Carolina Cabalín
@biorxivpreprint.bsky.social Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 6, 2025 at 2:46 AM
@biorxivpreprint.bsky.social Timing of immune checkpoint blockade shapes anti-tumor immunity via a clock-dependent chemokine axis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Carolina Cabalín
@biorxivpreprint.bsky.social T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 6, 2025 at 2:23 AM
@biorxivpreprint.bsky.social T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Carolina Cabalín
IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
November 2, 2025 at 10:48 PM
IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Carolina Cabalín
This Halloween I'm a vampire! 🧛♂️ hisss!!! Hisss! #HappyHalloween
November 1, 2025 at 1:46 AM
This Halloween I'm a vampire! 🧛♂️ hisss!!! Hisss! #HappyHalloween
Reposted by Carolina Cabalín
A 37-color spectral flow cytometry panel to characterize phenotype and cytokine expression in human intestinal T cells https://www.biorxiv.org/content/10.1101/2025.10.29.685441v1
October 31, 2025 at 5:16 PM
A 37-color spectral flow cytometry panel to characterize phenotype and cytokine expression in human intestinal T cells https://www.biorxiv.org/content/10.1101/2025.10.29.685441v1
Reposted by Carolina Cabalín
No one wants to do a postdoc anymore, they all want to rob the Louvre
October 27, 2025 at 2:50 AM
No one wants to do a postdoc anymore, they all want to rob the Louvre
This week has been full of wonderful scientific news ✨👩🏼🔬
October 25, 2025 at 2:55 PM
This week has been full of wonderful scientific news ✨👩🏼🔬
Reposted by Carolina Cabalín
Fat cat Friday (I’m allowed to post again)
October 24, 2025 at 2:27 PM
Fat cat Friday (I’m allowed to post again)
It was wonderful to reconnect at the NYC Postdoc Night Science! Such a great and inspiring conversation about how to give better talks and tell science stories that matter
October 16, 2025 at 10:05 AM
It was wonderful to reconnect at the NYC Postdoc Night Science! Such a great and inspiring conversation about how to give better talks and tell science stories that matter
Reposted by Carolina Cabalín
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Carolina Cabalín
A human pan-disease blood atlas of the circulating proteome
@science.org @buenoalvez.bsky.social
www.science.org/doi/epdf/10....
@science.org @buenoalvez.bsky.social
www.science.org/doi/epdf/10....
October 10, 2025 at 2:33 AM
A human pan-disease blood atlas of the circulating proteome
@science.org @buenoalvez.bsky.social
www.science.org/doi/epdf/10....
@science.org @buenoalvez.bsky.social
www.science.org/doi/epdf/10....
😍😍
Q.: What´s that?
A.: 16th century book nook
A.: 16th century book nook
October 10, 2025 at 3:54 PM
😍😍
Reposted by Carolina Cabalín
@biorxivpreprint.bsky.social TCR activation impairs CAR-T cytotoxicity against separate target cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 9, 2025 at 12:28 AM
@biorxivpreprint.bsky.social TCR activation impairs CAR-T cytotoxicity against separate target cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Carolina Cabalín
🚨New research highlight: study on managing immunotherapy side effects without weakening anti-tumor power!
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities
www.nature.com
April 11, 2025 at 9:20 AM
🚨New research highlight: study on managing immunotherapy side effects without weakening anti-tumor power!
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
Treg cells rule!
Nobel Prize in Physiology or Medicine, Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “ for their discoveries concerning peripheral immune tolerance
Related Posts bsky.app/search?q=%28+..
Related Posts bsky.app/search?q=%28+..
Nobel Prize in Physiology or Medicine 2025
The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
www.nobelprize.org
October 6, 2025 at 11:45 AM
Treg cells rule!
Reposted by Carolina Cabalín
Interested in learning how to be a good speaker and give effective talks? Season 2 of the NYC Postdoc Night Science Club begins October 15th. Join us NYC Postdocs for a 2hr workshop and maybe also a drink at a bar! Free registration (usually ~100 come): docs.google.com/forms/d/1dII...
September 30, 2025 at 1:40 PM
Interested in learning how to be a good speaker and give effective talks? Season 2 of the NYC Postdoc Night Science Club begins October 15th. Join us NYC Postdocs for a 2hr workshop and maybe also a drink at a bar! Free registration (usually ~100 come): docs.google.com/forms/d/1dII...
Reposted by Carolina Cabalín
Cis-elements required for Blimp1-mediated Tcf7 repression in control of memory CD8 T differentiation, where decoupling Tcf7 silencing from effector differentiation is permissive for effector gene expression @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
October 2, 2025 at 4:49 PM
Cis-elements required for Blimp1-mediated Tcf7 repression in control of memory CD8 T differentiation, where decoupling Tcf7 silencing from effector differentiation is permissive for effector gene expression @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Carolina Cabalín
S. aureus causes a basophil influx into skin-draining lymph nodes that heightens Th2 responses & increases serum IL-4, which enhances intestinal permeability, exaggerating oral anaphylaxis (dermatitis --> food allergy) @cp-immunity.bsky.social @harvardmed.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
September 25, 2025 at 3:33 PM
S. aureus causes a basophil influx into skin-draining lymph nodes that heightens Th2 responses & increases serum IL-4, which enhances intestinal permeability, exaggerating oral anaphylaxis (dermatitis --> food allergy) @cp-immunity.bsky.social @harvardmed.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Carolina Cabalín
A distinct population of CD8+ T cells expressing CD39 and CD73 accumulates with age and supports cancer progression @nataging.nature.com
www.nature.com/articles/s43...
www.nature.com/articles/s43...
A distinct population of CD8+ T cells expressing CD39 and CD73 accumulates with age and supports cancer progression - Nature Aging
Bodogai et al. identify a unique subset of CD8+ T cells expressing CD39 and CD73 that accumulate during aging and are recruited to and actively promote tumor progression by suppressing antitumor CD4+ T cells. Targeting their function or recruitment attenuates tumor growth in aged mice.
www.nature.com
September 26, 2025 at 3:00 AM
A distinct population of CD8+ T cells expressing CD39 and CD73 accumulates with age and supports cancer progression @nataging.nature.com
www.nature.com/articles/s43...
www.nature.com/articles/s43...
NIH establishes nation's first dedicated organoid development center to reduce reliance on animal modeling | National Institutes of Health (NIH) share.google/odgU3dnlWbTv...
NIH establishes nation's first dedicated organoid development center to reduce reliance on animal modeling
The Standardized Organoid Modeling Center aims to produce standardized protocols for organoid research, addressing reproducibility challenges.
share.google
September 25, 2025 at 9:46 PM
NIH establishes nation's first dedicated organoid development center to reduce reliance on animal modeling | National Institutes of Health (NIH) share.google/odgU3dnlWbTv...
Reposted by Carolina Cabalín
An optofluidic workflow for isolating antigen-specific functional CD8+ T cells with or without a prior knowledge of peptide-MHC specificities @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
September 20, 2025 at 4:37 PM
An optofluidic workflow for isolating antigen-specific functional CD8+ T cells with or without a prior knowledge of peptide-MHC specificities @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by Carolina Cabalín
CD103 facilitates the interaction of naive CD8+ T cells with E-cadherin-expressing dendritic cells that in turn provide cytokine-mediated cues to promote their differentiation into memory-phenotype effector T cells @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
September 15, 2025 at 4:54 PM
CD103 facilitates the interaction of naive CD8+ T cells with E-cadherin-expressing dendritic cells that in turn provide cytokine-mediated cues to promote their differentiation into memory-phenotype effector T cells @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Carolina Cabalín
IFN-induced senescent CD8+ T cells mediate immunotherapy nonresponsiveness in early TNBC, which can be reversed by nicotinamide mononucleotide
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
September 10, 2025 at 10:49 PM
IFN-induced senescent CD8+ T cells mediate immunotherapy nonresponsiveness in early TNBC, which can be reversed by nicotinamide mononucleotide
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Carolina Cabalín
Differentiation of naive into memory-phenotype CD8+ T cells does not promote the breakdown of peripheral tolerance in irradiated mice https://www.biorxiv.org/content/10.1101/2025.09.08.672311v1
September 9, 2025 at 5:16 AM
Differentiation of naive into memory-phenotype CD8+ T cells does not promote the breakdown of peripheral tolerance in irradiated mice https://www.biorxiv.org/content/10.1101/2025.09.08.672311v1