Bryjalab
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bryjalab.bsky.social
Bryjalab
@bryjalab.bsky.social
Laboratory of Cellular Communication
WNT signalling | CK1 | DVL | planar cell polarity | CLL | AML | melanoma | migration | choroid plexus |
Department of Experimental Biology, Faculty of Science, Masaryk University
https://www.sci.muni.cz/ofiz/en/bryja/
Also proud of our lab members — Olga Vondálová Blanářová, Michaela Chorvátová, Nela Kolčáková, Hana Plešingerová & Pavlína Janovská — for their excellent poster presentations! 👏
See you at the next edition! @csac-cz.bsky.social
October 12, 2025 at 7:53 PM
Big Bryjalab delegation at the 13th International Conference on Analytical Cytometry in beautiful Mikulov!

Many thanks to the organizers for such a wonderful meeting & Bike scientific discussion. 🚴‍♀️

Proud of our PhD students @antoniamikulova.bsky.social
and Štěpán Čada for their great talks! 🤗🧵
October 12, 2025 at 7:53 PM
🧐In a nutshell: CK1-mediated multisite phosphorylation of Dishevelled dramatically alters its bulk electrostatics, promoting DVL intramolecular coupling between the positively charged cleft of the DEP domain and the adjacent phosphorylated disordered region.
September 23, 2025 at 10:23 AM
Big day for Bryjalab yesterday! Mirek Micka & Tomáš Gybeľ nailed their defences — welcome to the PhD club! 🎓🔥 Thanks to everyone who supported them along the way and came to celebrate! 🎉🤗
September 13, 2025 at 1:59 PM
Day 2 of our Milestone minisymposium at @ceitec.eu in Brno was packed with excellent talks by Lucie Wolf from Stephane Angers’ lab at @utoronto.ca, followed by @cajaneklab.bsky.social and Víťa as the closing speaker. 🔥
September 13, 2025 at 8:42 AM
The science marathon continues. 🏃
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓
September 11, 2025 at 7:04 PM
Grind stays real – Víťa and @petrakompanikova.bsky.social went straight from the V4SDB Meeting 2025 to the European Brain Barrier Meeting in Bern, where Petra presented her work on the hindbrain choroid plexus. 🐁 Big thanks to the organizers and community for the warm first-time welcome! 😇 #EBBM2025
September 10, 2025 at 12:50 PM
Last week we joined the @v4sdb.bsky.social Meeting 2025 in the beautiful High Tatras 🌄 with an amazing lineup of speakers and posters 🔥 So good to see this society still rocking!
September 9, 2025 at 6:49 AM
First-ever CK1 Protein Kinase Family conference took place in Brno, bringing together nearly 80 researchers from around the world to share the latest findings on CK1 biology, disease links, and therapeutic potential. Thanks for the inspiring talks, posters & great networking – see you next time! 🎉🥳
August 14, 2025 at 12:28 PM
📢 Greetings from Dundee! Our PhD student Tomáš Gybeľ sends his best from his internship in the Sapkota lab at the University of Dundee, where he is studying CK1 and the Fam83 protein family in Wnt signaling. 🌍🔬 Big thanks to Prof. Sapkota and his team for their warm welcome and support! 🤗
February 3, 2025 at 11:15 AM
Bryjalab attended the 25th Prague Hematology Days 🩸, presenting our work on ROR1+ B cells in CLL, CK1 inhibitors in AML, and the effect of CK1 inhibition + Venetoclax on specific AML clones. 👩‍⚕️👩‍🔬 Huge thanks to the organizers for the chance to share our research with scientists and clinicians! 🤗
January 28, 2025 at 6:26 AM
Hi Bluesky! 🌌 We are Bryjalab – the Laboratory of Cellular Communication 🧬 at Masaryk University, Brno, Czech Republic. From development 🐣 to disease 🩺, we explore the mechanisms and effects of Wnt signaling cascades. 🧵 Follow us for more Wnt updates! 🚀
January 19, 2025 at 5:19 PM