@brainresilience.bsky.social
“We’re making a helmet people can wear that delivers ultrasound to the brain, and we plan to initiate clinical testing of this protocol in the next few months,” said Raag Airan.
With Knight Initiative support, they plan to test it on people soon.
🔗 brainresilience.stanford.edu/news/new-ult...
With Knight Initiative support, they plan to test it on people soon.
🔗 brainresilience.stanford.edu/news/new-ult...
November 10, 2025 at 11:47 PM
“We’re making a helmet people can wear that delivers ultrasound to the brain, and we plan to initiate clinical testing of this protocol in the next few months,” said Raag Airan.
With Knight Initiative support, they plan to test it on people soon.
🔗 brainresilience.stanford.edu/news/new-ult...
With Knight Initiative support, they plan to test it on people soon.
🔗 brainresilience.stanford.edu/news/new-ult...
Fantastic talks at yesterday's seminar!
Ted Wilson - Unveiling early Alzheimer’s: biomarkers and breakthroughs on the path to brain resilience.
Raag Airan - Ultrasonic debris clearance for improving neurofluid flow and decreasing neuroinflammation.
Ted Wilson - Unveiling early Alzheimer’s: biomarkers and breakthroughs on the path to brain resilience.
Raag Airan - Ultrasonic debris clearance for improving neurofluid flow and decreasing neuroinflammation.
November 5, 2025 at 1:00 AM
Fantastic talks at yesterday's seminar!
Ted Wilson - Unveiling early Alzheimer’s: biomarkers and breakthroughs on the path to brain resilience.
Raag Airan - Ultrasonic debris clearance for improving neurofluid flow and decreasing neuroinflammation.
Ted Wilson - Unveiling early Alzheimer’s: biomarkers and breakthroughs on the path to brain resilience.
Raag Airan - Ultrasonic debris clearance for improving neurofluid flow and decreasing neuroinflammation.
Thank you to our wonderful speakers and everyone who joined us at the Fall 2025 Symposium and Poster Session! It was a day full of insights into the latest research on healthy brain aging, resilience, and various neuroscience studies at Stanford.
October 13, 2025 at 6:57 PM
Thank you to our wonderful speakers and everyone who joined us at the Fall 2025 Symposium and Poster Session! It was a day full of insights into the latest research on healthy brain aging, resilience, and various neuroscience studies at Stanford.
Our Fall Symposium is today! We look forward to our poster session and talks by:
John W. Day, Soyon Hon @soyonhonglab.bsky.social,
Alina Isakova, Andrew C. Yang, Hongkui Seng @hongkuizeng.bsky.social, and Xuchen Zhang.
John W. Day, Soyon Hon @soyonhonglab.bsky.social,
Alina Isakova, Andrew C. Yang, Hongkui Seng @hongkuizeng.bsky.social, and Xuchen Zhang.
October 9, 2025 at 6:13 PM
Our Fall Symposium is today! We look forward to our poster session and talks by:
John W. Day, Soyon Hon @soyonhonglab.bsky.social,
Alina Isakova, Andrew C. Yang, Hongkui Seng @hongkuizeng.bsky.social, and Xuchen Zhang.
John W. Day, Soyon Hon @soyonhonglab.bsky.social,
Alina Isakova, Andrew C. Yang, Hongkui Seng @hongkuizeng.bsky.social, and Xuchen Zhang.
Great talks at our recent seminar! Featuring:
Kristy Zera - Blocking the VLA4/VCAM1 axis prevents infarct-induced neurodegeneration by reducing neuroinflammation & promoting vascular integrity
Carla Shatz - Convergence of signals for pruning at a synaptic receptor implicated in Alzheimer's Disease
Kristy Zera - Blocking the VLA4/VCAM1 axis prevents infarct-induced neurodegeneration by reducing neuroinflammation & promoting vascular integrity
Carla Shatz - Convergence of signals for pruning at a synaptic receptor implicated in Alzheimer's Disease
October 8, 2025 at 6:46 PM
Great talks at our recent seminar! Featuring:
Kristy Zera - Blocking the VLA4/VCAM1 axis prevents infarct-induced neurodegeneration by reducing neuroinflammation & promoting vascular integrity
Carla Shatz - Convergence of signals for pruning at a synaptic receptor implicated in Alzheimer's Disease
Kristy Zera - Blocking the VLA4/VCAM1 axis prevents infarct-induced neurodegeneration by reducing neuroinflammation & promoting vascular integrity
Carla Shatz - Convergence of signals for pruning at a synaptic receptor implicated in Alzheimer's Disease
Join us on Oct 9 at a symposium featuring brain resilience and aging research, including a clinical presentation with a patient’s perspective, poster session, and social! Registration required.
Stanford affiliates, sign up to present a poster by Oct 2.
brainresilience.stanford.edu/events/knigh...
Stanford affiliates, sign up to present a poster by Oct 2.
brainresilience.stanford.edu/events/knigh...
September 25, 2025 at 5:40 PM
Join us on Oct 9 at a symposium featuring brain resilience and aging research, including a clinical presentation with a patient’s perspective, poster session, and social! Registration required.
Stanford affiliates, sign up to present a poster by Oct 2.
brainresilience.stanford.edu/events/knigh...
Stanford affiliates, sign up to present a poster by Oct 2.
brainresilience.stanford.edu/events/knigh...
Our Brain Resilience Seminars are back! Yesterday, Jacob Simon shared his research on "A novel toolset for understanding neuromodulation," and Joe Winer discussed "Effects of ⍺-synuclein pathology in normal aging and Alzheimer’s disease." Thank you to all who joined and participated in the Q&A.
September 9, 2025 at 5:39 PM
Our Brain Resilience Seminars are back! Yesterday, Jacob Simon shared his research on "A novel toolset for understanding neuromodulation," and Joe Winer discussed "Effects of ⍺-synuclein pathology in normal aging and Alzheimer’s disease." Thank you to all who joined and participated in the Q&A.
Syed has been a vital part of our Brain Resilience Lab as the Primary Neuroanatomist and @stanfordmedicine.bsky.social’s Primary Brain Dissectionist & Coordinator, supporting research brains and rapid brain autopsies. He’s now beginning his PhD at the University of Washington . Congrats Syed!
September 5, 2025 at 10:48 PM
Syed has been a vital part of our Brain Resilience Lab as the Primary Neuroanatomist and @stanfordmedicine.bsky.social’s Primary Brain Dissectionist & Coordinator, supporting research brains and rapid brain autopsies. He’s now beginning his PhD at the University of Washington . Congrats Syed!
Why do some dementia treatments work in mice but not in people?
At @stanfordneuro.bsky.social, Vanessa Langness, Danielle Simmons, and Frank Longo reviewed 400+ preclinical studies to identify key differences in timing, study design, and disease stage.
brainresilience.stanford.edu/news/why-pro...
At @stanfordneuro.bsky.social, Vanessa Langness, Danielle Simmons, and Frank Longo reviewed 400+ preclinical studies to identify key differences in timing, study design, and disease stage.
brainresilience.stanford.edu/news/why-pro...
August 28, 2025 at 6:17 PM
Why do some dementia treatments work in mice but not in people?
At @stanfordneuro.bsky.social, Vanessa Langness, Danielle Simmons, and Frank Longo reviewed 400+ preclinical studies to identify key differences in timing, study design, and disease stage.
brainresilience.stanford.edu/news/why-pro...
At @stanfordneuro.bsky.social, Vanessa Langness, Danielle Simmons, and Frank Longo reviewed 400+ preclinical studies to identify key differences in timing, study design, and disease stage.
brainresilience.stanford.edu/news/why-pro...
Researching the aging brain starts with knowing its structure.
Syed Bukhari, Primary Neuroanatomist at the Brain Resilience Lab, led a hands-on anatomy workshop for Stanford researchers—sharing expertise and building connections across the brain resilience community.
Syed Bukhari, Primary Neuroanatomist at the Brain Resilience Lab, led a hands-on anatomy workshop for Stanford researchers—sharing expertise and building connections across the brain resilience community.
August 20, 2025 at 7:04 PM
Researching the aging brain starts with knowing its structure.
Syed Bukhari, Primary Neuroanatomist at the Brain Resilience Lab, led a hands-on anatomy workshop for Stanford researchers—sharing expertise and building connections across the brain resilience community.
Syed Bukhari, Primary Neuroanatomist at the Brain Resilience Lab, led a hands-on anatomy workshop for Stanford researchers—sharing expertise and building connections across the brain resilience community.
In the Brain Resilience Lab, Shon has contributed to flagship projects that map the molecular landscape of brain aging and led collaborations using next-generation sequencing, histology & spatial transcriptomics. He’s now starting his neuroscience PhD at @ucsanfrancisco.bsky.social. Congrats Shon!
August 15, 2025 at 10:18 PM
In the Brain Resilience Lab, Shon has contributed to flagship projects that map the molecular landscape of brain aging and led collaborations using next-generation sequencing, histology & spatial transcriptomics. He’s now starting his neuroscience PhD at @ucsanfrancisco.bsky.social. Congrats Shon!
By integrating innovative lysosomal omics and ferroptosis-targeted interventions, Dr. Monther Abu-Remaileh and Dr. Scott Dixon aim to identify strategies to restore lysosomal function, protect against neurodegeneration, and enhance brain resilience.
brainresilience.stanford.edu/our-science/...
brainresilience.stanford.edu/our-science/...
July 31, 2025 at 6:21 PM
By integrating innovative lysosomal omics and ferroptosis-targeted interventions, Dr. Monther Abu-Remaileh and Dr. Scott Dixon aim to identify strategies to restore lysosomal function, protect against neurodegeneration, and enhance brain resilience.
brainresilience.stanford.edu/our-science/...
brainresilience.stanford.edu/our-science/...
What makes the brain resilient, and how can research help more people stay cognitively healthy as they age?
Highlights include:
🧠 Early biomarkers
🧪 Lysosomal function
💉 Shingles vaccine & reduced dementia risk
📣 Lived experience
📊 72 Stanford posters
brainresilience.stanford.edu/news/knight-...
Highlights include:
🧠 Early biomarkers
🧪 Lysosomal function
💉 Shingles vaccine & reduced dementia risk
📣 Lived experience
📊 72 Stanford posters
brainresilience.stanford.edu/news/knight-...
July 15, 2025 at 7:17 PM
What makes the brain resilient, and how can research help more people stay cognitively healthy as they age?
Highlights include:
🧠 Early biomarkers
🧪 Lysosomal function
💉 Shingles vaccine & reduced dementia risk
📣 Lived experience
📊 72 Stanford posters
brainresilience.stanford.edu/news/knight-...
Highlights include:
🧠 Early biomarkers
🧪 Lysosomal function
💉 Shingles vaccine & reduced dementia risk
📣 Lived experience
📊 72 Stanford posters
brainresilience.stanford.edu/news/knight-...
“We’ve developed a blood-based indicator of the age of your organs,” said Tony Wyss-Coray. “With this indicator, we can assess the age of an organ today & predict the odds of your getting a disease associated with that organ 10 years later.”
Read more: med.stanford.edu/news/all-new...
Read more: med.stanford.edu/news/all-new...
July 9, 2025 at 7:06 PM
“We’ve developed a blood-based indicator of the age of your organs,” said Tony Wyss-Coray. “With this indicator, we can assess the age of an organ today & predict the odds of your getting a disease associated with that organ 10 years later.”
Read more: med.stanford.edu/news/all-new...
Read more: med.stanford.edu/news/all-new...
Why do some older adults remember better than others, even when equally healthy? A new Knight-supported study led by Jintao Sheng & Anthony Wagner shows 2 distinct pathways that shape memory in aging:
🧠Early Alzheimer’s tau
🧠Moment-to-moment attention
🔗 brainresilience.stanford.edu/news/two-roa...
🧠Early Alzheimer’s tau
🧠Moment-to-moment attention
🔗 brainresilience.stanford.edu/news/two-roa...
June 25, 2025 at 7:26 PM
Why do some older adults remember better than others, even when equally healthy? A new Knight-supported study led by Jintao Sheng & Anthony Wagner shows 2 distinct pathways that shape memory in aging:
🧠Early Alzheimer’s tau
🧠Moment-to-moment attention
🔗 brainresilience.stanford.edu/news/two-roa...
🧠Early Alzheimer’s tau
🧠Moment-to-moment attention
🔗 brainresilience.stanford.edu/news/two-roa...
Stanford scientists are uncovering the cellular functions that go awry in degenerative brain disorders and identifying therapies that could treat them in the lab of chemical engineer and Knight Initiative affiliate Monther Abu-Remaileh @abu-remaileh.bsky.social.
🔗 news.stanford.edu/stories/2025...
🔗 news.stanford.edu/stories/2025...
June 23, 2025 at 7:02 PM
Stanford scientists are uncovering the cellular functions that go awry in degenerative brain disorders and identifying therapies that could treat them in the lab of chemical engineer and Knight Initiative affiliate Monther Abu-Remaileh @abu-remaileh.bsky.social.
🔗 news.stanford.edu/stories/2025...
🔗 news.stanford.edu/stories/2025...
Tanya Paull of @utaustin.bsky.social gave a talk on "DNA damage and cerebellar ataxia: roles for transcription stress, PARP, and R-loops in ATM-associated neurodegeneration" in an Aging Research seminar organized by the Knight Initiative and the Paul F. Glenn Center for Biology of Aging Research.
June 10, 2025 at 6:56 PM
Tanya Paull of @utaustin.bsky.social gave a talk on "DNA damage and cerebellar ataxia: roles for transcription stress, PARP, and R-loops in ATM-associated neurodegeneration" in an Aging Research seminar organized by the Knight Initiative and the Paul F. Glenn Center for Biology of Aging Research.
What does surgery reveal about brain resilience?
Anesthesiologists Martin Angst & Igor Feinstein are studying older adults before, during & after cardiac surgery to explore how stress impacts the brain—why some recover cognitively while others decline.
brainresilience.stanford.edu/news/under-l...
Anesthesiologists Martin Angst & Igor Feinstein are studying older adults before, during & after cardiac surgery to explore how stress impacts the brain—why some recover cognitively while others decline.
brainresilience.stanford.edu/news/under-l...
June 9, 2025 at 5:49 PM
What does surgery reveal about brain resilience?
Anesthesiologists Martin Angst & Igor Feinstein are studying older adults before, during & after cardiac surgery to explore how stress impacts the brain—why some recover cognitively while others decline.
brainresilience.stanford.edu/news/under-l...
Anesthesiologists Martin Angst & Igor Feinstein are studying older adults before, during & after cardiac surgery to explore how stress impacts the brain—why some recover cognitively while others decline.
brainresilience.stanford.edu/news/under-l...
At a recent seminar, Hannah Ennerfelt shared a talk on "Peripheral immune drivers of cognitive decline in aging and Alzheimer's disease," and Jintao Sheng discussed "Top-down attention & Alzheimer’s pathology impact cortical selectivity during learning, influencing episodic memory in older adults."
June 4, 2025 at 7:26 PM
At a recent seminar, Hannah Ennerfelt shared a talk on "Peripheral immune drivers of cognitive decline in aging and Alzheimer's disease," and Jintao Sheng discussed "Top-down attention & Alzheimer’s pathology impact cortical selectivity during learning, influencing episodic memory in older adults."
Thanks to all who joined us at our Year-End Symposium and Research Showcase to learn about promising studies on brain resilience supported by the Knight Initiative.
Congratulations to Vanessa Doulames, Lauren Duan, Shuke Xiao, and Shon Alimukhamedov, the 2025 poster session winners!
Congratulations to Vanessa Doulames, Lauren Duan, Shuke Xiao, and Shon Alimukhamedov, the 2025 poster session winners!
May 13, 2025 at 7:16 PM
Thanks to all who joined us at our Year-End Symposium and Research Showcase to learn about promising studies on brain resilience supported by the Knight Initiative.
Congratulations to Vanessa Doulames, Lauren Duan, Shuke Xiao, and Shon Alimukhamedov, the 2025 poster session winners!
Congratulations to Vanessa Doulames, Lauren Duan, Shuke Xiao, and Shon Alimukhamedov, the 2025 poster session winners!
Geldsetzer shares that the findings have now been replicated in other health systems, including in Australia, using varied data sources and outcome measures. His team is now investigating why the shingles vaccine may help protect against dementia.
May 7, 2025 at 11:52 PM
Geldsetzer shares that the findings have now been replicated in other health systems, including in Australia, using varied data sources and outcome measures. His team is now investigating why the shingles vaccine may help protect against dementia.
Mormino shares early results from the 7-year Stanford Aging and Memory Study. With improved tools, researchers can now detect biomarkers of neurodegeneration earlier and deepen our understanding of cognitive resilience and decline.
May 7, 2025 at 11:42 PM
Mormino shares early results from the 7-year Stanford Aging and Memory Study. With improved tools, researchers can now detect biomarkers of neurodegeneration earlier and deepen our understanding of cognitive resilience and decline.
Now we hear from neuroscientist Beth Mormino, a leader of the Stanford Memory and Aging Study of healthy aging, who will tell us about “Deep(er) phenotyping of our local human aging cohorts.”
May 7, 2025 at 11:39 PM
Now we hear from neuroscientist Beth Mormino, a leader of the Stanford Memory and Aging Study of healthy aging, who will tell us about “Deep(er) phenotyping of our local human aging cohorts.”
Brain Resilience Postdoctoral Scholar Jian Xiong of the Abu Remaileh lab discusses how dysfunction in lysosomes—the cell’s waste disposal system—can drive neurodegeneration, and why restoring their function may help slow brain aging.
May 7, 2025 at 11:24 PM
Brain Resilience Postdoctoral Scholar Jian Xiong of the Abu Remaileh lab discusses how dysfunction in lysosomes—the cell’s waste disposal system—can drive neurodegeneration, and why restoring their function may help slow brain aging.
To illustrate how brain rhythms may affect cognition, Purdon sings a few bars of “Fly Me to the Moon.” EEG data collected by his team during surgical anesthesia suggest these brain-wave recordings may reflect brain health and could be further developed to help measure resilience.
May 7, 2025 at 11:05 PM
To illustrate how brain rhythms may affect cognition, Purdon sings a few bars of “Fly Me to the Moon.” EEG data collected by his team during surgical anesthesia suggest these brain-wave recordings may reflect brain health and could be further developed to help measure resilience.