Christoph Bock Lab @ CeMM & MedUni Vienna
@bocklab.bsky.social
Technology-driven biomedical research at CeMM Research Center for Molecular Medicine & MedUni Vienna #cancer #immunology #bioinformatics #AI #singlecell #CRISPR
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
Multimodal learning enables chat-based exploration of single-cell data - @bocklab.bsky.social @cemm.oeaw.ac.at @meduniwien.ac.at go.nature.com/3WPGJnW
Multimodal learning enables chat-based exploration of single-cell data - Nature Biotechnology
CellWhisperer uses multimodal learning of transcriptomes and text to answer questions about single-cell RNA-sequencing data.
go.nature.com
November 11, 2025 at 4:58 PM
Multimodal learning enables chat-based exploration of single-cell data - @bocklab.bsky.social @cemm.oeaw.ac.at @meduniwien.ac.at go.nature.com/3WPGJnW
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
November 11, 2025 at 12:52 PM
🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
🗨️Chat with your cells, explore #CellWhisperer!
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
November 11, 2025 at 10:05 AM
🗨️Chat with your cells, explore #CellWhisperer!
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
CeMM PI Christoph Bock (@bocklab.bsky.social) together with @meduniwien.ac.at & @stanna-ccri.bsky.social have developed a new #AI tool that lets scientists explore single-cell data using plain English.
➡️ https://bit.ly/3JQqe87
📄 https://bit.ly/3WJCxGi
🧬 CAR T cells demonstrate the power of engineered cells as therapeutics. But they fail for most patients. Can CRISPR help here? Our new paper in Nature (www.nature.com/articles/s41...) presents a screening platform to optimize immunotherapies & discover boosters of CAR T cell function. (1/13)
September 24, 2025 at 6:42 PM
🧬 CAR T cells demonstrate the power of engineered cells as therapeutics. But they fail for most patients. Can CRISPR help here? Our new paper in Nature (www.nature.com/articles/s41...) presents a screening platform to optimize immunotherapies & discover boosters of CAR T cell function. (1/13)
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
We’re thrilled to announce that the "High-Content CRISPR Screening" conference will take place on March 18–19, 2026, in Vienna, Austria.
The registration is now open via the conference website:
lnkd.in/d8KACZy5
Meet the Speaker: Christoph Bock
@bocklab.bsky.social
The registration is now open via the conference website:
lnkd.in/d8KACZy5
Meet the Speaker: Christoph Bock
@bocklab.bsky.social
September 9, 2025 at 2:11 PM
We’re thrilled to announce that the "High-Content CRISPR Screening" conference will take place on March 18–19, 2026, in Vienna, Austria.
The registration is now open via the conference website:
lnkd.in/d8KACZy5
Meet the Speaker: Christoph Bock
@bocklab.bsky.social
The registration is now open via the conference website:
lnkd.in/d8KACZy5
Meet the Speaker: Christoph Bock
@bocklab.bsky.social
🛡️How do macrophages tailor their defenses to different pathogens? Our new paper in @cp-cellsystems.bsky.social combines dense multi-omics time series with high‐content CRISPR screens (CROP-seq) to map the regulatory landscape underlying macrophage immune responses: www.cell.com/cell-systems... (1/9)
August 12, 2025 at 4:46 PM
🛡️How do macrophages tailor their defenses to different pathogens? Our new paper in @cp-cellsystems.bsky.social combines dense multi-omics time series with high‐content CRISPR screens (CROP-seq) to map the regulatory landscape underlying macrophage immune responses: www.cell.com/cell-systems... (1/9)
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
🧬How do #macrophages respond so quickly to pathogens?
A new study by CeMM & @meduniwien.ac.at researchers, led by @bocklab.bsky.social & @mfarlik.bsky.social, reveals key regulators of immune responses using gene editing & machine learning.
➡️ More info: bit.ly/40p5ABe
🔗 Study: bit.ly/4lwEAIm
A new study by CeMM & @meduniwien.ac.at researchers, led by @bocklab.bsky.social & @mfarlik.bsky.social, reveals key regulators of immune responses using gene editing & machine learning.
➡️ More info: bit.ly/40p5ABe
🔗 Study: bit.ly/4lwEAIm
August 8, 2025 at 3:03 PM
🧬How do #macrophages respond so quickly to pathogens?
A new study by CeMM & @meduniwien.ac.at researchers, led by @bocklab.bsky.social & @mfarlik.bsky.social, reveals key regulators of immune responses using gene editing & machine learning.
➡️ More info: bit.ly/40p5ABe
🔗 Study: bit.ly/4lwEAIm
A new study by CeMM & @meduniwien.ac.at researchers, led by @bocklab.bsky.social & @mfarlik.bsky.social, reveals key regulators of immune responses using gene editing & machine learning.
➡️ More info: bit.ly/40p5ABe
🔗 Study: bit.ly/4lwEAIm
🔬 Toward histopathology 2.0: spatial transcriptomes inferred from routine diagnostic H&E images + a chat interface for cell-resolution histopathology through English language. (1/6)
July 18, 2025 at 10:40 PM
🔬 Toward histopathology 2.0: spatial transcriptomes inferred from routine diagnostic H&E images + a chat interface for cell-resolution histopathology through English language. (1/6)
POSTDOC OPPPORTUNITY: We are recruiting via the CeMM postdoc program. Looking for 3 types of candidates:
1. Bioinformatics & systems biology (e.g., immunology, neurobiology or cancer)
2. ML/AI methods for biology & precision medicine
3. Technology development & bioengineering
Details below (1/3)
1. Bioinformatics & systems biology (e.g., immunology, neurobiology or cancer)
2. ML/AI methods for biology & precision medicine
3. Technology development & bioengineering
Details below (1/3)
June 2, 2025 at 4:21 PM
POSTDOC OPPPORTUNITY: We are recruiting via the CeMM postdoc program. Looking for 3 types of candidates:
1. Bioinformatics & systems biology (e.g., immunology, neurobiology or cancer)
2. ML/AI methods for biology & precision medicine
3. Technology development & bioengineering
Details below (1/3)
1. Bioinformatics & systems biology (e.g., immunology, neurobiology or cancer)
2. ML/AI methods for biology & precision medicine
3. Technology development & bioengineering
Details below (1/3)
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)
May 6, 2025 at 12:08 PM
AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)
AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)
May 6, 2025 at 12:08 PM
AI in medicine ready for takeoff 🤖🚁 We flew a drone through the Institute of Artificial Intelligence @MedUniWien. Join us for the trip and watch our team at "work". #AI #biomedicine #innovation #makingof (1/2)
CeMM's new Research Report is online - a piece of art as always (link below). Each research group selected a mathematical formula that symbolizes their research and visualized it in a live-staged group picture. We picked Shannon entropy, as biomedicine is all about information (and sometimes messy)
March 25, 2025 at 3:03 PM
CeMM's new Research Report is online - a piece of art as always (link below). Each research group selected a mathematical formula that symbolizes their research and visualized it in a live-staged group picture. We picked Shannon entropy, as biomedicine is all about information (and sometimes messy)
Job Posting: Senior NGS Technology & Deputy Head of the Biomedical Sequencing Facility (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences & Medical University of Vienna)
February 13, 2025 at 7:50 AM
Job Posting: Senior NGS Technology & Deputy Head of the Biomedical Sequencing Facility (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences & Medical University of Vienna)
Could a CRISPR screen help you discover new biology? Should you consider high-content readouts such as single-cell or spatial profiling? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field & now over 225,000 views/downloads.
High-content CRISPR screening - Nature Reviews Methods Primers
CRISPR screening is a high-throughput approach for identifying genes, pathways and mechanisms involved in a given phenotype or biological process. High-content read-outs of these screens, such as imag...
www.nature.com
February 13, 2025 at 7:29 AM
Could a CRISPR screen help you discover new biology? Should you consider high-content readouts such as single-cell or spatial profiling? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field & now over 225,000 views/downloads.
LAST CHANCE TO APPLY - DEADLINE 21 January 2025
HIRING: We offer several PhD student positions in the CeMM PhD Program. Looking for 3 types of candidates: experimental systems biology in cancer & immunity; bioinformatics & biomedical ML/AI; tech-dev & bioengineering. Join an a highly collaborative lab in molecular medicine. Details below (1/4)
January 20, 2025 at 7:55 AM
LAST CHANCE TO APPLY - DEADLINE 21 January 2025
Reposted by Christoph Bock Lab @ CeMM & MedUni Vienna
Thrilled to see our work with the @bocklab.bsky.social featured in 'The Scientist'!
It's a really great read and builds on an interview I had with the @kamalnahas.bsky.social.
www.the-scientist.com/an-ai-lab-pa...
It's a really great read and builds on an interview I had with the @kamalnahas.bsky.social.
www.the-scientist.com/an-ai-lab-pa...
An AI Lab Partner Helps Sift Through Transcriptomics Data
Big omics datasets can be overwhelming for researchers with limited programming skills, but texting with a new AI chatbot could help them wade through their results.
www.the-scientist.com
December 19, 2024 at 2:37 PM
Thrilled to see our work with the @bocklab.bsky.social featured in 'The Scientist'!
It's a really great read and builds on an interview I had with the @kamalnahas.bsky.social.
www.the-scientist.com/an-ai-lab-pa...
It's a really great read and builds on an interview I had with the @kamalnahas.bsky.social.
www.the-scientist.com/an-ai-lab-pa...
HIRING: We offer several PhD student positions in the CeMM PhD Program. Looking for 3 types of candidates: experimental systems biology in cancer & immunity; bioinformatics & biomedical ML/AI; tech-dev & bioengineering. Join an a highly collaborative lab in molecular medicine. Details below (1/4)
December 18, 2024 at 12:12 PM
HIRING: We offer several PhD student positions in the CeMM PhD Program. Looking for 3 types of candidates: experimental systems biology in cancer & immunity; bioinformatics & biomedical ML/AI; tech-dev & bioengineering. Join an a highly collaborative lab in molecular medicine. Details below (1/4)
We are recruiting a Tenure-track Assistant Professor "Machine Learning in the Life Sciences" at the Medical University of Vienna. We will nominate the top candidate for a € 1.8 million starting grant by a Viennese foundation. Deadline: Dec 31st. Details: medical-epigenomics.org/files/Tenure...
December 2, 2024 at 9:35 AM
We are recruiting a Tenure-track Assistant Professor "Machine Learning in the Life Sciences" at the Medical University of Vienna. We will nominate the top candidate for a € 1.8 million starting grant by a Viennese foundation. Deadline: Dec 31st. Details: medical-epigenomics.org/files/Tenure...
🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)
October 18, 2024 at 9:32 AM
🗨️ WANNA TALK TO YOUR CELLS? Try out CellWhisperer – our new multimodal AI that turns single-cell RNA-seq analysis into a conversation. No coding needed, just chat in plain English. Short walkthrough below. Web app & bioRxiv preprint linked in the thread. Let's dive in! (1/9)
We are recruiting a PhD student in ML/AI methods and biomedical applications, within @ELLISforEurope & @humancellatlas. Keywords: Perturbation modeling, generative AI, synthetic biology, cancer immunotherapy, precision medicine. Great environment in Vienna. medical-epigenomics.org/files/PhD_St...
September 11, 2024 at 8:58 AM
We are recruiting a PhD student in ML/AI methods and biomedical applications, within @ELLISforEurope & @humancellatlas. Keywords: Perturbation modeling, generative AI, synthetic biology, cancer immunotherapy, precision medicine. Great environment in Vienna. medical-epigenomics.org/files/PhD_St...
Ready for an expedition into the unknown? We are recruiting two postdocs through the CeMM Postdoc Program. Our group combines ML/AI in bioinformatics, CRISPR & single-cell technology development, and biomedical applications in cancer & immunity. Details: www.cemm.at/fileadmin/us...
August 8, 2024 at 8:12 AM
Ready for an expedition into the unknown? We are recruiting two postdocs through the CeMM Postdoc Program. Our group combines ML/AI in bioinformatics, CRISPR & single-cell technology development, and biomedical applications in cancer & immunity. Details: www.cemm.at/fileadmin/us...
Thanks Nature Immunology for highlighting our paper with a Research Briefing, explaining the broader relevance with a bit of backstory and quotes from a reviewer and the editor. The paper is open access, but the Research Briefing is not – please use the following link for free access: rdcu.be/dGnH0
Baseline JAK–STAT signaling maintains immune cell homeostasis
Nature Immunology - Homeostatic immune cells remain perpetually vigilant against pathogens. We found that baseline JAK–STAT signaling supports the characteristic transcriptional and...
rdcu.be
May 2, 2024 at 1:16 PM
Thanks Nature Immunology for highlighting our paper with a Research Briefing, explaining the broader relevance with a bit of backstory and quotes from a reviewer and the editor. The paper is open access, but the Research Briefing is not – please use the following link for free access: rdcu.be/dGnH0
🧬 WHAT KEEPS IMMUNE CELLS AWAKE & ATTENTIVE? It’s their neighbors – stimulation from the tissue environment. We profiled epigenomes & transcriptomes of 12 JAK-STAT mutant mice and found surprisingly strong effects at homeostasis. Paper just out in Nature Immunology: www.nature.com/articles/s41...
April 24, 2024 at 1:34 PM
🧬 WHAT KEEPS IMMUNE CELLS AWAKE & ATTENTIVE? It’s their neighbors – stimulation from the tissue environment. We profiled epigenomes & transcriptomes of 12 JAK-STAT mutant mice and found surprisingly strong effects at homeostasis. Paper just out in Nature Immunology: www.nature.com/articles/s41...
Would CRISPR screening help you discover new biology? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field. Published in 2022, this review has already >150,000 views/downloads (according to the journal). Thank you!
High-content CRISPR screening - Nature Reviews Methods Primers
CRISPR screening is a high-throughput approach for identifying genes, pathways and mechanisms involved in a given phenotype or biological process. High-content read-outs of these screens, such as imag...
www.nature.com
February 5, 2024 at 10:29 PM
Would CRISPR screening help you discover new biology? Check out our methods primer for a hands-on guide (www.nature.com/articles/s43...), co-authored by many experts in the field. Published in 2022, this review has already >150,000 views/downloads (according to the journal). Thank you!
DEADLINE APPROACHING: We are recruiting a Senior Bioinformatician / Biomedical Data Scientist for our research group at the CeMM Research Center for Molecular Medicine & the Institute of Artificial Intelligence of the Medical University of Vienna. Details: cemm.onlyfy.jobs/job/qy9y9wl6
January 24, 2024 at 10:42 AM
DEADLINE APPROACHING: We are recruiting a Senior Bioinformatician / Biomedical Data Scientist for our research group at the CeMM Research Center for Molecular Medicine & the Institute of Artificial Intelligence of the Medical University of Vienna. Details: cemm.onlyfy.jobs/job/qy9y9wl6