Benjamin Helm, PhD, MS, CGC
Benjamin Helm, PhD, MS, CGC
@bmhgcepi.bsky.social
Genetic Counselor, Epidemiology, Cardiovascular Genetics
Makes sense. A practical challenge seems to be, that to allow prediction, the spline basis functions need to be known, but this may not be readily available (in SAS)
July 31, 2025 at 12:34 PM
Currently using SAS, and natural cubic (RCS); wasn't sure if you need to know specifics of the spline functions used in the background for fitting the line
July 30, 2025 at 1:54 AM
are there examples of what the prediction equation would look like?
July 29, 2025 at 11:06 PM
I loved this resource, thanks so much! I am currently working on a log-reg model with a var w/ a nonlinear relationship with my outcome... my spline variable has 3 knots (resulting in two beta coefficients in my model equation. I am wanting to use it for future predictions --
July 29, 2025 at 11:06 PM
This is an excellent resource. Thanks! I had question regarding what the full derived prediction model equation would look like, when incorporating the splined variable with three knots (two coefficients). I will message you directly.
July 19, 2025 at 12:49 PM
This post is great. I'd definitely consider citing/referencing it in later discussions/guides for research. Thanks for sharing!
July 5, 2025 at 1:36 PM
Would there be a recording available, or content? Would love to see if able. I appreciate your perspectives for the feather ruffling stuff!
June 2, 2025 at 11:40 AM
I'd love to get a "Quantitative GC Group" together sometime to meet/informally discuss topics in this area -- would be so cool @j9austin.bsky.social
May 15, 2025 at 3:17 PM
And our spoken language/vernacular is often challenged by conversations in this area -- so recommendations for clarity or conversations is always welcome
May 15, 2025 at 3:17 PM
Thank you 😀 -- there is SO much to try to cover, so we missed some interesting topics like causality, definitions of confounders/confounding, multivariable adjustment, bias, and so much more (DAGs!); def share feedback for future iterations @j9austin.bsky.social
May 15, 2025 at 3:17 PM
👍👍appreciate it!
March 29, 2025 at 10:29 AM