Bishoy Hanna
@bishoyh.bsky.social
Computational biologist, mostly...
Reposted by Bishoy Hanna
Reposted by Bishoy Hanna
#FriendsOrFoes?! Lee, Naora &co show @cp-cancercell.bsky.social that neutrophils produce NETs in peritoneal fat during ovarian cancer favoring metastasis formation. NETs displace CD22 from SHP1 in innate-like B cells driving IL10 production, Treg differentiation, & metastasis formation!
Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10
Lee et al. show that neutrophil extracellular traps (NETs) establish the pre-metastatic niche in the omentum by recruiting innate-like B cells and eliciting IL-10 production in these cells through inactivating SHP-1 and generating reactive oxygen species, thereby expanding Tregs. These findings underscore the potential of inhibiting NETs for metastasis prevention.
dlvr.it
January 3, 2025 at 4:00 PM
#FriendsOrFoes?! Lee, Naora &co show @cp-cancercell.bsky.social that neutrophils produce NETs in peritoneal fat during ovarian cancer favoring metastasis formation. NETs displace CD22 from SHP1 in innate-like B cells driving IL10 production, Treg differentiation, & metastasis formation!
Reposted by Bishoy Hanna
Resurrection of a diatom after 7000 years from anoxic Baltic Sea sediment academic.oup.com/ismej/advanc... #jcampubs
January 3, 2025 at 4:03 PM
Resurrection of a diatom after 7000 years from anoxic Baltic Sea sediment academic.oup.com/ismej/advanc... #jcampubs
Reposted by Bishoy Hanna
Excited to share “Bin Chicken”, substantially improving genome recovery through rational metagenomic assembly. Applied to public 🌍 metagenomes, it recovered 24,000 novel species 🦠, including 6 novel phyla.
doi.org/10.1101/2024...
@wwood @rhysnewell @CMR_QUT
🧵1/6
doi.org/10.1101/2024...
@wwood @rhysnewell @CMR_QUT
🧵1/6
November 26, 2024 at 2:45 AM
Excited to share “Bin Chicken”, substantially improving genome recovery through rational metagenomic assembly. Applied to public 🌍 metagenomes, it recovered 24,000 novel species 🦠, including 6 novel phyla.
doi.org/10.1101/2024...
@wwood @rhysnewell @CMR_QUT
🧵1/6
doi.org/10.1101/2024...
@wwood @rhysnewell @CMR_QUT
🧵1/6
Reposted by Bishoy Hanna
Teloschistes chrysophthalmus, a lichen protected under the Canadian Species At Risk Act, on an oak in southern Manitoba (2022)
November 26, 2024 at 2:22 AM
Teloschistes chrysophthalmus, a lichen protected under the Canadian Species At Risk Act, on an oak in southern Manitoba (2022)
Reposted by Bishoy Hanna
Excited to work with TACC, PSU, and UCSD to provide a cloud workspace for NIH Common Fund projects! tacc.utexas.edu/news/latest-...
TACC Receives NIH Award to Develop Cloud Workspace Implementation Center
New workspace to make data management sustainable for life sciences data analysis
tacc.utexas.edu
November 26, 2024 at 2:41 AM
Excited to work with TACC, PSU, and UCSD to provide a cloud workspace for NIH Common Fund projects! tacc.utexas.edu/news/latest-...
Reposted by Bishoy Hanna
The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 25, 2024 at 12:19 PM
The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Bishoy Hanna
Very pleased to announce that our manuscript describing @jgi.doe.gov 's Secondary Metabolism Collaboratory is now available! SMC has been up and active for a while now, but I'm really excited to start seeing more activity on here. Lots more to come.
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
The secondary metabolism collaboratory: a database and web discussion portal for secondary metabolite biosynthetic gene clusters
Abstract. Secondary metabolites are small molecules produced by all corners of life, often with specialized bioactive functions with clinical and environme
doi.org
November 14, 2024 at 5:31 PM
Very pleased to announce that our manuscript describing @jgi.doe.gov 's Secondary Metabolism Collaboratory is now available! SMC has been up and active for a while now, but I'm really excited to start seeing more activity on here. Lots more to come.
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...