Tobias Lenz
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biotobi.bsky.social
Tobias Lenz
@biotobi.bsky.social
Professor of Evolutionary Immunogenomics @uni-hamburg.de

Evolutionary Genetics, Eco-Immunology, Host-Parasite Coevolution, Evolutionary Medicine, MHC/HLA. Only research-related posts.

http://www.biologie.uni-hamburg.de/evolutionaryimmunogenomics
Reposted by Tobias Lenz
Establish your own independent research group as Group Leader - AI in Biology.

We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology.

embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
September 11, 2025 at 7:24 AM
Reposted by Tobias Lenz
“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast
pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
pod.link
September 11, 2025 at 3:04 PM
Reposted by Tobias Lenz
Applications due Monday September 15 for the International Event Grants! These grants support symposia, workshops, courses, and other evolutionary biology events, including virtual events. Learn more and apply now: rb.gy/76fgi
September 11, 2025 at 3:16 PM
Reposted by Tobias Lenz
I've written a short blog post introducing "The Art of Visualization with ggplot2"!

This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots!

nrennie.rbind.io/blog/art-of-...

#RStats #DataViz #TidyTuesday
Introducing The Art of Visualization with ggplot2 – Nicola Rennie
I’ve written a book! This blog post gives a brief introduction to The Art of Visualization with ggplot2, a book of data visualization case studies showing the end-to-end process of building charts, st...
nrennie.rbind.io
September 11, 2025 at 2:32 PM
Reposted by Tobias Lenz
📣New today!
📄Haplotype analysis reveals pleiotropic disease associations in the HLA region
🧑‍🤝‍🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
Haplotype analysis reveals pleiotropic disease associations in the HLA region
The HLA region plays an important role in human health but is often excluded in large-scale GWASs. We performed haplotype-based associations from genotype data to investigate pleiotropy across thousan...
www.cell.com
July 10, 2025 at 4:51 PM
Reposted by Tobias Lenz
Some PIs will stop at nothing to motivate their lab members. 🧪
July 12, 2025 at 11:41 AM
Join the annual meeting of the Society for Immune Polymorphism (SIP), November 3-5, Netherlands!

A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species.

Early bird/Abstract deadline is Aug 15:
sip-sassenheim.org
July 11, 2025 at 1:44 PM
Reposted by Tobias Lenz
📣 2 #Immunology #Summer_Schools that might be of interest to you:

If you are working on adaptive immune receptor repertoire:
ut.ee/en/content/c...

If you want to get deeper into new advances in Immunology:
focis2025.univ-rouen.fr/page.php?pag...

#ImmunoSky
Computational Immunology Summer School
Join the Computational Immunology Summer School to explore the fascinating world of Adaptive Immune Receptor Repertoires (AIRRs), mastering cutting-edge bioinformatics tools and lab techniques to uncover the secrets of immune system diversity.
ut.ee
April 11, 2025 at 8:55 AM
Reposted by Tobias Lenz
'Compared with the patients’ doctors, the AI model more often failed to detect the presence of disease in Black patients or women, as well in those 40yrs or younger. Wn the researchers looked at race and sex combined, Black women fell to the bottom, with the AI not detecting disease in half of them'
AI models miss disease in Black and female patients
Analysis of chest x-rays underscores need for monitoring artificial intelligence tools for bias, experts say
www.science.org
April 11, 2025 at 9:06 AM
Reposted by Tobias Lenz
Interested in starting your research group in AI and applications to science? Check out our upcoming online event for DFG funded opportunities in Goettingen!
The DFG is funding independent research groups in AI (tinyurl.com/36f5m6kd). If you're interested in coming to Göttingen (Germany) by applying for one of these groups, we have an online event to inform you what the process is and how we could support you (tinyurl.com/yfpeambm). Check it out!
Förderinitiative „Künstliche Intelligenz“
tinyurl.com
April 11, 2025 at 11:39 AM
Reposted by Tobias Lenz
Your research matters! Contribute to the future of #EvolutionaryBiology by submitting your Abstract to #ESEB2025.

🔬 Explore over 50 topics, including:
#Evolution in all its aspects
#Genetics & #Genomics
✅ New Frontiers and more!

📩 Submit now: eseb2025.com/call-for-abs...
April 9, 2025 at 12:38 PM
Reposted by Tobias Lenz
📢 new paper alert for the primate and genomics nerds. telomere to telomere ape genomes. I led MHC annotations on this work w/ @biotobi.bsky.social and @meyerbritta.bsky.social And hey it’s my first nature paper 🥳 www.nature.com/articles/s41...
Complete sequencing of ape genomes - Nature
Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...
www.nature.com
April 9, 2025 at 3:19 PM
Reposted by Tobias Lenz
Medicine on a Larger Scale: Global Histories of Social Medicine, eds @ahlie.bsky.social, Jeremy Greene, and me, will be available open access from @cambridgeup.bsky.social in May 2025. In a world of growing health inequity, radical social medicine has never been more urgent!
#histstm #histmed #sts
Medicine on a Larger Scale
Cambridge Core - History of Medicine - Medicine on a Larger Scale
www.cambridge.org
April 8, 2025 at 5:06 AM
Reposted by Tobias Lenz
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Join Us! | King Lab
Are you interested in joining the King Lab? More information here!
www.zoology.ubc.ca
March 31, 2025 at 1:22 AM
Reposted by Tobias Lenz
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.
March 28, 2025 at 11:15 AM
Proudly presenting Dr. Artemis Efstratiou, who recently defended her PhD. She worked on variation of #MHC immune genes and dynamics of the T cell receptor repertoire in sticklebacks under different experimental conditions. Congratulations, Artemis! 🥳🎉 www.biologie.uni-hamburg.de/en/forschung...
March 26, 2025 at 7:17 AM
I just noticed this new header above the website of #MolecularEcologyResources. I'm sure that there are vast numbers of 'healthcare professionals' who will want to read our paper on MHC diversity in sticklebacks (😂), but what about the other few remaining scientsts? Just asking, @wiley.com ...
March 25, 2025 at 11:07 AM
Reposted by Tobias Lenz
Hello Blue world!
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.

So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
Admixture as a source for HLA variation in Neolithic European farming communities - Genome Biology
Background The northern European Neolithic is characterized by two major demographic events: immigration of early farmers from Anatolia at 7500 years before present, and their admixture with local wes...
doi.org
March 24, 2025 at 2:13 PM
Reposted by Tobias Lenz
🚀 Registrations are open: 2025 SymbNET PhD Summer School on Host-Microbe Symbioses, Oeiras (Lisbon), Portugal
👉 gimm.idloom.events/phd-summer-s...

Please help us sharing this announcement 📣

@gimmfoundation.bsky.social #CBR @moorefound.bsky.social @crc1182.bsky.social #CIFAR
PhD Summer School on Host-Microbe Symbioses 2025
Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...
gimm.idloom.events
March 6, 2025 at 2:08 PM
Reposted by Tobias Lenz
To all fish immunologists, if you haven't read this @jimmunol.bsky.social paper from Adam Hurlstone lab in #zebrafish which I know it's a few years old please do, the more I read it the more gems I find in it journals.aai.org/jimmunol/art...
CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes
Abstract. CD4+ T cells are at the nexus of the innate and adaptive arms of the immune system. However, little is known about the evolutionary history of CD
journals.aai.org
January 20, 2025 at 5:03 PM
Reposted by Tobias Lenz
Age-Related Dynamics and Spectral Characteristics of the TCRβ Repertoire in Healthy Children: Implications for Immune Aging onlinelibrary.wiley.com/doi/10.1111/...
Age‐Related Dynamics and Spectral Characteristics of the TCRβ Repertoire in Healthy Children: Implications for Immune Aging
Developmental dynamics of TCRβ diversity in Chinese children. We analyzed TCRβ repertoire diversity in 325 healthy Chinese children (0–18 years) through TCRβ sequencing and flow cytometry analysis (n...
onlinelibrary.wiley.com
March 19, 2025 at 7:38 PM
Reposted by Tobias Lenz
www.journals.uchicago.edu/doi/pdf/10.1...

‘Petrous Fever’ - not an inner ear problem, but a pretty unique paper collating opinions and reflections on the aDNA ‘gold rush’ from museum curators, archaeologists and anthropologists with some insightful responses at the end.
University of Chicago Press Journals: Cookie absent
www.journals.uchicago.edu
December 5, 2024 at 10:14 PM
Reposted by Tobias Lenz
In school, you probably learned that human cells have 46 chromosomes, which is 2 copies of 23 chromosomes, sometimes called 'diploid' or '2n'.

But there are other 'ploidies' in your cells.

To start with, 80+% of your cells have NO chromosomes: red blood cells or 'erythrocytes'...
December 30, 2024 at 1:52 PM
Reposted by Tobias Lenz
'A new study in this issue of PLOS Biology examined the fidelity of various brain organoid protocols in reference to human primary developing brain by gene co-expression relationships with million-scale collection of public scRNA-seq data sets.'
journals.plos.org/plosbiology/...
Lessons about physiological relevance learned from large-scale meta-analysis of co-expression networks in brain organoids
Despite the recent rapid advances in neural organoid culture systems, it is unclear how closely they mimic primary human tissue physiology. This Primer explores a new study in PLOS Biology that conduc...
journals.plos.org
December 25, 2024 at 5:20 PM