Ben Mayro
@benjaminmayro.bsky.social
NCI K00 Fellow at UTSW in the Tagliabracci lab. Interested in cool enzymes and PTMs
Reposted by Ben Mayro
I’m excited to share my first paper in the Farnung lab, in which we report four cryo-EM structures of the human DNA replication machinery engaging with and progressing into a nucleosome.
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
April 6, 2025 at 10:43 AM
I’m excited to share my first paper in the Farnung lab, in which we report four cryo-EM structures of the human DNA replication machinery engaging with and progressing into a nucleosome.
Excited to amplify an awesome project that
@majumdar.bsky.social & James Ye championed over the last few years in the TagLab! They leveraged a bacteria ubiquitination system to create a clever/fun proximity ligation approach. A cool tool to add to anyone's interaction toolbelt! tinyurl.com/5bjjr49j
@majumdar.bsky.social & James Ye championed over the last few years in the TagLab! They leveraged a bacteria ubiquitination system to create a clever/fun proximity ligation approach. A cool tool to add to anyone's interaction toolbelt! tinyurl.com/5bjjr49j
Bacterial ubiquitin ligase engineered for small molecule and protein target identification
The Legionella SidE effectors ubiquitinate host proteins independently of the canonical E1-E2 cascade. Here we engineer the SidE ligases to develop a modular proximity ligation approach for the identi...
www.biorxiv.org
March 24, 2025 at 3:37 PM
Excited to amplify an awesome project that
@majumdar.bsky.social & James Ye championed over the last few years in the TagLab! They leveraged a bacteria ubiquitination system to create a clever/fun proximity ligation approach. A cool tool to add to anyone's interaction toolbelt! tinyurl.com/5bjjr49j
@majumdar.bsky.social & James Ye championed over the last few years in the TagLab! They leveraged a bacteria ubiquitination system to create a clever/fun proximity ligation approach. A cool tool to add to anyone's interaction toolbelt! tinyurl.com/5bjjr49j