Begum Gokerkucuk
begumgoker.bsky.social
Begum Gokerkucuk
@begumgoker.bsky.social
Reposted by Begum Gokerkucuk
🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1
September 18, 2025 at 4:58 PM
Reposted by Begum Gokerkucuk
Time for some insights into our latest #preprint

Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠
🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1
September 22, 2025 at 7:25 PM
Reposted by Begum Gokerkucuk
Diving “Google earth mode 🌍” in a Shigella infected cell 🔬🔎
Together with @m-albert.bsky.social
Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale.

@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social

#CryoEM
May 26, 2025 at 9:46 AM
Reposted by Begum Gokerkucuk
Our latest paper is out! Congratulations to @leaswistak.bsky.social et al for this amazing #cryoET work that elucidates the initial stages of #T3SS dependent vacuolar damage during #Shigella infection. We will do a deep-dive later! journals.plos.org/plosbiology/...
May 6, 2025 at 1:06 PM
Reposted by Begum Gokerkucuk
I wrote a little step-by-step guide for straightforward and simple visualization of timelapse lifetime data (specific for acquisition of lifetime data with a Leica scope):
github.com/JoachimGoedh...
April 8, 2025 at 7:50 AM
Reposted by Begum Gokerkucuk
We are live on Bluesky! Looking forward to sharing some great science :)
February 10, 2025 at 8:53 AM