basgrootkoerkamp.bsky.social
@basgrootkoerkamp.bsky.social
Reposted
Can #Video Grading of Bile Duct Anastomoses During Robotic 🤖 #Pancreatoduodenectomy Predicts Bile Leak (BL)?

✅ Videos from 259 pts robotic HJ: 6.9% B/C BL
✅ OSATS score <21 assoc with BL
✅ The rate of BL was 5.1% for OSATS>21 vs 12.5% for OSATS ≤21

▶️ journals.lww.com/annalsofsurg...
February 17, 2025 at 9:39 PM
Reposted
Failure to Rescue After Resection of Perhilar Cholangiocarcinoma in an International Multicenter Cohort ⁦‪@AnnSurgOncol‬⁩

link.springer.com/article/10.1...
Failure to Rescue After Resection of Perhilar Cholangiocarcinoma in an International Multicenter Cohort - Annals of Surgical Oncology
Background Failure to rescue (FTR) is defined as the inability to prevent death after the development of a complication. FTR is a parameter in evaluating multidisciplinary postoperative complication m...
link.springer.com
February 19, 2025 at 12:30 PM
Reposted
🧪 CA19.9 response after induction FOLFIRINOX for LAPC @bjsurgery.bsky.social

1k LAPC chemo ➡️ restaging 23% M1 😢 24% underwent surgery 🪡

📉 Baseline CA19.9 Not predictor of survival

📈 CA19.9 after induction / decrease 80% best survival

academic.oup.com/bjs/article/...

@bjsacademy.bsky.social
February 20, 2025 at 6:44 AM
Reposted
Hepatocellular carcinoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up ⁦‪⁦‪@Annals_Oncology‬⁩

www.sciencedirect.com/science/arti...
Hepatocellular carcinoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
www.sciencedirect.com
February 20, 2025 at 4:22 PM
Reposted
🧬 RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

🎯 A milestone one in @nature.com

🦠 Responders with vaccine induced t-cells have prolonged RFS compared to non responders

💉 Vaccine for PDAC not a dream anymore

www.nature.com/articles/s41...

#PancreaSky #HPBSky
February 22, 2025 at 11:06 AM
Reposted
📝 Want to know how to write a clinical paper?

We have a 4️⃣ part series dedicated to just that!

📽️ Watch part 2️⃣, taught by @villesallinen.bsky.social, Editor-in-Chief, of @bjsopen.bsky.social here
➡️ https://buff.ly/4b3QNzN

#SurgSky #MedSky
How to write a clinical paper – Part 2 of 4
Short BJS Course – Part 2 of 4 Ville Sallinen, Editor-in-Chief, BJS Open
buff.ly
February 23, 2025 at 10:13 AM
Reposted
The Duration of Immunotherapy for Mismatch Repair–Deficient Cancers ⁦‪@NEJM‬⁩

www.nejm.org/doi/full/10....
The Duration of Immunotherapy for Mismatch Repair–Deficient Cancers | NEJM
An analysis of published studies suggests that a longer duration of immune checkpoint inhibitor therapy is associated with a higher incidence of complete response among patients with mismatch ...
www.nejm.org
February 23, 2025 at 3:23 PM
Reposted
The pleasure of finding things out is one of the greatest rewards of the human spirit.
January 4, 2025 at 7:22 PM
Reposted
Perioperative Corticosteroids 💊 to reduce complications in pancreas surgery?

🧐 Meta analysis 5 studies / 1.4k pts @annsurgoncology.bsky.social

Corticosteroids🫸🫷no dicrease morbidity / fistula / mortality

💡 What about mitigation strategis in high risk!? #HPBSky

link.springer.com/article/10.1...
January 5, 2025 at 3:29 PM
Reposted
There is no learning without having to pose a question. And a question requires doubt.
January 3, 2025 at 5:51 PM
Reposted
Let us start 2025 in a positive mood: here are 10 methods things researchers can worry *less* about in 2025
a countdown clock with the number 10 in the center
ALT: a countdown clock with the number 10 in the center
media.tenor.com
December 23, 2024 at 10:36 AM
Reposted
Nationwide 🇳🇱 outcome #robot 🤖 vs #laparoscopic #liver #surgery ?

🔑 Robot ⬇️conversion
🔑 Robot ⬇️ hospital stay
🔑 Robot ⬇️ blood loss
🔑 Robot benefits mostly based on less conversions

▶️ journals.lww.com/aosopen/full...

@eahpba.bsky.social @ihpba.bsky.social
December 23, 2024 at 5:55 PM
Reposted
PDAC: advances in tumour microenvironment, microbiome and AI ⁦‪@NatRevGastroHep‬⁩

www.nature.com/articles/s41...
PDAC: advances in tumour microenvironment, microbiome and AI - Nature Reviews Gastroenterology & Hepatology
Pancreatic cancer remains one of the most challenging malignancies, with a very poor prognosis. Current research is focused on elucidating the role of the tumour microenvironment and the microbiome in...
www.nature.com
December 24, 2024 at 12:25 PM
Reposted
Our MOBILE2 trial Top4 viewed paper @jama.com/surgery with >30k views! And total two papers from Finland🇫🇮 on Top10 list. Many more trials already running, quite a few in the pipeline to be started, several new ideas under marinade!

read.alerts.jamanetwork.com/csb/Public/s...
Most Viewed Articles 2024
read.alerts.jamanetwork.com
December 25, 2024 at 9:52 AM
Reposted
Play with ideas the way children play with toys—without fear of breaking them.
December 20, 2024 at 8:26 PM
Reposted
2️⃣0️⃣2️⃣4️⃣ Pancreas Wrapped 🎄

6️⃣ June 🍇 How to prevent IPMN progression to cancer?!

🫸 🚬 Quit smoking is THE answer!

Smoke correlates with HGD and invasive cancer 🚨

www.dldjournalonline.com/article/S159...

#HPBSky #PancreasSky #SurgSky
December 21, 2024 at 9:45 AM
Reposted
Long term outcomes in EDPAC 4. The median OS was 29.5 months (27.5-32.1) for all patients, 28.4 months (25.2-32.0) in the gemcitabine group and 31.6 months (26.5-38.0) in the GemCap group

ascopubs.org/doi/10.1200/...
Pancreatic Adenocarcinoma: Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial
PURPOSEThe ESPAC4 trial showed that adjuvant chemotherapy with gemcitabine plus capecitabine (GemCap) produced longer overall survival (OS) than gemcitabine monotherapy. Subsequently, the PRODIGE24-CC...
ascopubs.org
December 8, 2024 at 1:30 AM
Reposted
A new study in @cellpress.bsky.social Immunity from the lab of Dr. Benjamin Greenbaum provides insights into how #PancreaticCancer cells accommodate active retrotransposons without triggering the innate immune response. #oncsky #medsky
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms
Overexpression of transposable elements is a common feature of cancer. Sun, You, et al. show that, in pancreatic ductal adenocarcinoma, tumor cells adapt through different mechanisms to mitigate a spe...
www.cell.com
November 27, 2024 at 6:57 PM
Reposted
Adjuvant chemotherapy for adenocarcinoma arising from intraductal papillary mucinous neoplasia: multicentre ADENO-IPMN study

academic.oup.com/bjs/article/...
Validate User
academic.oup.com
November 28, 2024 at 2:56 PM
Reposted
Today #JAMAsurg: long term outcomes #ESCAPE RCT: early #surgery remains superior to #endoscopy first in pts with wide-duct #chronic #pancreatitis

✅ Lower Izbicki pain scores
✅ Lower number of reinterventions
✅ Lower VAS pain scores
✅ Higher patient satisfaction

▶️ jamanetwork.com/journals/jam...
November 20, 2024 at 8:23 PM