I was lucky to go dog sledding earlier this year which, naturally, made me think about the Central Limit Theorem

Quick posts about the CLT: www.johnlees.me/posts/dogs-c...
(and some pictures of dogs)

Trying to find an image of vaccine conjugation and google mostly coming up with the one from this paper www.mdpi.com/2076-393X/9/...

Terrible resolution. I thought the font seemed really familiar too

Why does this 'publisher' look like it is trying to sell me a zombie knife

Had a great time at the SMBE satellite meeting on pangenomes and pathogen transmission which we hosted in Tokyo last week!
We had 87 on site attendees and 48 remote participants, with sessions on metagenomics, selection, emerging diseases, pangenomes and modelling.

Now published in bioinformatics, CELEBRIMBOR 'pangenomes from metagenomes'
academic.oup.com/bioinformati...
I think reviewer comments helped make it better, so worth another look (at fig 1 particularly!)

Sam has then wrapped it all up in a nice snakemake pipeline CELEBRIMBOR (Core ELEment Bias Removal In Metagenome Binned ORthologs) which lets you go from MAGs to pangenome

github.com/bacpop/CELEB...

Here, Joel instead made a probabilistic model to use these to readjust gene frequencies to make them more accurate, allowing parameterised choices of how to do so, in the package core gene threshold (cgt) github.com/bacpop/cgt

It's called GNASTy (Graph-based Nanopore Adaptive Sampling Typing, pronounced ‘nasty’)

Here is my yearly writeup/review of video games from the past year www.johnlees.me/posts/review...
Best one: Chants of Sennar

New blog post
I gave a talk ~4yrs ago 'Multiple horses for multiple courses' about interfacing multiple programming languages for research software (particuarly python and C++). I recap that here, and end with some reflections on following my own advice:
www.bacpop.org/blog/horses/

Hello new platform, please see my recent adverts

Postdoc ad currently open:
www.embl.org/jobs/positio...

Recent paper:
genome.cshlp.org/content/earl...
www.ebi.ac.uk/about/news/r...