Ayushi Rehman
@ayushirehman.bsky.social
Juggling paralogs for PhD!
Interested in gene regulation, RNA Biology, Neurodegenerative disorders.
Fiction lover 🧙🔍!
RBP-Lab @IITGuwahati
Interested in gene regulation, RNA Biology, Neurodegenerative disorders.
Fiction lover 🧙🔍!
RBP-Lab @IITGuwahati
Reposted by Ayushi Rehman
My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely.
jobs.colorado.edu/jobs/JobDeta...
jobs.colorado.edu/jobs/JobDeta...
October 17, 2025 at 4:00 PM
My fantastic department at CU Boulder is hiring a tenure-track Assistant Professor! This is a broad search spanning nearly all areas of biology. Applications are due Nov 13, 2025. Feel free to reach out to me with questions, and please share widely.
jobs.colorado.edu/jobs/JobDeta...
jobs.colorado.edu/jobs/JobDeta...
Reposted by Ayushi Rehman
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Reposted by Ayushi Rehman
My awesome Drosophila colleague Akhila Rajan at Fred Hutch (Seattle) is recruiting both a staff scientist and a postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs/30062/j...
Fred Hutchinson Cancer Center
Fred Hutch is dedicated to the elimination of cancer and related diseases as causes of human suffering and death.
careers-fhcrc.icims.com
September 17, 2025 at 1:05 AM
My awesome Drosophila colleague Akhila Rajan at Fred Hutch (Seattle) is recruiting both a staff scientist and a postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs/30062/j...
Reposted by Ayushi Rehman
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
September 8, 2025 at 8:56 AM
Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...
Reposted by Ayushi Rehman
🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance
🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry.
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬
Register now ✍️ www.pasteur.fr/en/education...
September 7, 2025 at 10:49 AM
🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance
Reposted by Ayushi Rehman
Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multivalent interactions with CCR4–NOT and PABPC1 determine mRNA repression efficiency by tristetraprolin - Nature Communications
Deadenylation leads to mRNA decay, with PABPC1 protecting the poly(A) tail, while tristetraprolin and CCR4–NOT promote deadenylation. Here, the authors describe how these three proteins interact to re...
www.nature.com
August 13, 2025 at 5:32 PM
Delighted to present our second paper of the year. This one explores the molecular mechanism of TTP, a key post-transcriptional regulator of AU-rich mRNAs. Work led and coordinated by @filippekovic.bsky.social, in collaboration with Perry Blackshear.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ayushi Rehman
Le Cong, one of the pioneers of applying #CRISPR in eukaryotic cells, and his team now have developed an agent to apply #ChatGPT #LLM technology to automate and enhance CRISPR-based gene-editing design and data analysis.
In #nature Biomedical Engineering.
www.nature.com/articles/s41...
In #nature Biomedical Engineering.
www.nature.com/articles/s41...
CRISPR-GPT for agentic automation of gene-editing experiments - Nature Biomedical Engineering
An agent-based large language model (LLM) tool helps with CRISPR-based gene-editing experimental design and analysis.
www.nature.com
August 8, 2025 at 7:15 AM
Le Cong, one of the pioneers of applying #CRISPR in eukaryotic cells, and his team now have developed an agent to apply #ChatGPT #LLM technology to automate and enhance CRISPR-based gene-editing design and data analysis.
In #nature Biomedical Engineering.
www.nature.com/articles/s41...
In #nature Biomedical Engineering.
www.nature.com/articles/s41...
Reposted by Ayushi Rehman
📝🤳 Become an event reporter! In exchange for a fee waiver you'll need to post social media updates from the conference and write a report summarising the meeting 📷✍🏻
✅ All on-site and virtual conferences at EMBL Heidelberg
Find out more and apply 👉🏻 https://s.embl.org/reporter
@embl.org
✅ All on-site and virtual conferences at EMBL Heidelberg
Find out more and apply 👉🏻 https://s.embl.org/reporter
@embl.org
June 19, 2025 at 7:33 AM
📝🤳 Become an event reporter! In exchange for a fee waiver you'll need to post social media updates from the conference and write a report summarising the meeting 📷✍🏻
✅ All on-site and virtual conferences at EMBL Heidelberg
Find out more and apply 👉🏻 https://s.embl.org/reporter
@embl.org
✅ All on-site and virtual conferences at EMBL Heidelberg
Find out more and apply 👉🏻 https://s.embl.org/reporter
@embl.org
Reposted by Ayushi Rehman
If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!
June 4, 2025 at 9:01 PM
If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!
Reposted by Ayushi Rehman
Why we love it at the Vienna BioCenter–hear it directly from our fellows!
The VIP³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment.
Apply now: training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
@viennabiocenter.bsky.social @impvienna.bsky.social
The VIP³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment.
Apply now: training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
@viennabiocenter.bsky.social @impvienna.bsky.social
June 4, 2025 at 8:18 AM
Why we love it at the Vienna BioCenter–hear it directly from our fellows!
The VIP³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment.
Apply now: training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
@viennabiocenter.bsky.social @impvienna.bsky.social
The VIP³ call is open–16 fully-funded, three-year postdoctoral fellowships in an interdisciplinary environment.
Apply now: training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
@viennabiocenter.bsky.social @impvienna.bsky.social
Reposted by Ayushi Rehman
I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics
EVE Meeting Expression of Interest
forms.gle
May 27, 2025 at 11:53 AM
I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics
Reposted by Ayushi Rehman
Wanted to join #EMBLRBP but couldn't?
👩🔬 📷 Get first-hand insights from our event reporter @ayushirehman.bsky.social here ➡️ www.embl.org/about/info/c...
#lifesciencetraining #RBPs
👩🔬 📷 Get first-hand insights from our event reporter @ayushirehman.bsky.social here ➡️ www.embl.org/about/info/c...
#lifesciencetraining #RBPs
May 14, 2025 at 7:36 AM
Wanted to join #EMBLRBP but couldn't?
👩🔬 📷 Get first-hand insights from our event reporter @ayushirehman.bsky.social here ➡️ www.embl.org/about/info/c...
#lifesciencetraining #RBPs
👩🔬 📷 Get first-hand insights from our event reporter @ayushirehman.bsky.social here ➡️ www.embl.org/about/info/c...
#lifesciencetraining #RBPs
Reposted by Ayushi Rehman
Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!
tomoguide.github.io
Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!
tomoguide.github.io
Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪
Welcome to TomoGuide
A step-by-step Cryo-ET guide
tomoguide.github.io
May 6, 2025 at 4:27 PM
Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!
tomoguide.github.io
Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!
tomoguide.github.io
Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪
Reposted by Ayushi Rehman
Check out this fun preview of my postdoctoral work! It highlights our findings plus lots of intriguing questions that I’m super excited to tackle in the coming years. (And the model is beautiful! Thank you! 🧑🎨 )
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors
In a recent issue of Molecular Cell, Genoyer et al. show that during West Nile virus infection, escaped, cytoplasmic, anti-genomic negative-sense viral RNA triggers an antiviral response via RIG-I activation. Flaviviruses typically hide −vRNA in replication compartments to avoid detection, but some −vRNA leaks, possibly aided by viral capsid proteins.
dlvr.it
April 18, 2025 at 6:19 PM
Check out this fun preview of my postdoctoral work! It highlights our findings plus lots of intriguing questions that I’m super excited to tackle in the coming years. (And the model is beautiful! Thank you! 🧑🎨 )
Reposted by Ayushi Rehman
Happy to see this work published in RNA, and thanks to the editors for the interview/Meet the First Author Feature! Surprisingly, we found that mutating an RNA binding protein's ability to bind RNA did not remove all biological function. #RNAsky #RNAbiology.
rnajournal.cshlp.org/content/31/5...
rnajournal.cshlp.org/content/31/5...
The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
rnajournal.cshlp.org
April 16, 2025 at 3:19 PM
Happy to see this work published in RNA, and thanks to the editors for the interview/Meet the First Author Feature! Surprisingly, we found that mutating an RNA binding protein's ability to bind RNA did not remove all biological function. #RNAsky #RNAbiology.
rnajournal.cshlp.org/content/31/5...
rnajournal.cshlp.org/content/31/5...
Reposted by Ayushi Rehman
Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
April 11, 2025 at 8:35 AM
Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
Reposted by Ayushi Rehman
A nearly 9 year effort to design and implement new CLIP-based technologies to define multimeric protein assemblies on RNA.
Enables ‘watching’ of RNP assemblies inside living cells
Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com
www.nature.com/articles/s41...
Enables ‘watching’ of RNP assemblies inside living cells
Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com
www.nature.com/articles/s41...
March 26, 2025 at 5:40 PM
A nearly 9 year effort to design and implement new CLIP-based technologies to define multimeric protein assemblies on RNA.
Enables ‘watching’ of RNP assemblies inside living cells
Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com
www.nature.com/articles/s41...
Enables ‘watching’ of RNP assemblies inside living cells
Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com
www.nature.com/articles/s41...
Reposted by Ayushi Rehman
Check out our preprint at BioRxiv revealing mechanisms of mRNP assembly during translation repression: (www.biorxiv.org/content/10.1...). Great collaboration with Olivier Duss (@olivierduss.bsky.social). Great Work Marco Payr (@marcopayr.bsky.social) and thanks for the video, explaining our paper.
April 11, 2025 at 4:35 AM
Check out our preprint at BioRxiv revealing mechanisms of mRNP assembly during translation repression: (www.biorxiv.org/content/10.1...). Great collaboration with Olivier Duss (@olivierduss.bsky.social). Great Work Marco Payr (@marcopayr.bsky.social) and thanks for the video, explaining our paper.
A sneak peek into my experience at #EMBLRBP
Grateful for all the wonderful people I got to interact with ❤️ @events.embl.org @sloanmegan.bsky.social @shikhas.bsky.social
www.embl.org/about/info/c...
Grateful for all the wonderful people I got to interact with ❤️ @events.embl.org @sloanmegan.bsky.social @shikhas.bsky.social
www.embl.org/about/info/c...
April 10, 2025 at 1:20 PM
A sneak peek into my experience at #EMBLRBP
Grateful for all the wonderful people I got to interact with ❤️ @events.embl.org @sloanmegan.bsky.social @shikhas.bsky.social
www.embl.org/about/info/c...
Grateful for all the wonderful people I got to interact with ❤️ @events.embl.org @sloanmegan.bsky.social @shikhas.bsky.social
www.embl.org/about/info/c...
Reposted by Ayushi Rehman
An interesting perspective and framework: #RNA condensates-not individual RNAs-may have acted as replicative units in early life. RNAs in condensate recruit similar RNAs, then the condensate divides once it reaches a critical size.
#RNAsky
#RNAsky
An RNA condensate model for the origin of life
The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA Wor…
www.sciencedirect.com
April 10, 2025 at 12:28 AM
Reposted by Ayushi Rehman
Next Thursday we are hosting a virtual RNA Club with Adam Cawte and Isaia Berbieri! Please join us for some cool RNA talks 😎🧬 Checkout our other threads for a little sneak preview 👀 Thank you to our sponsors @rnasociety.bsky.social and Lexogen !
April 3, 2025 at 10:12 AM
Next Thursday we are hosting a virtual RNA Club with Adam Cawte and Isaia Berbieri! Please join us for some cool RNA talks 😎🧬 Checkout our other threads for a little sneak preview 👀 Thank you to our sponsors @rnasociety.bsky.social and Lexogen !
Reposted by Ayushi Rehman
Our latest paper is out in NAR! 🥳
In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates.
Read:
academic.oup.com/nar/article-...
In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates.
Read:
academic.oup.com/nar/article-...
DGCR8 haploinsufficiency leads to primate-specific RNA dysregulation and pluripotency defects
Abstract. The 22q11.2 deletion syndrome (22qDS) is a human disorder where the majority of clinical manifestations originate during embryonic development. 2
academic.oup.com
March 27, 2025 at 10:13 AM
Our latest paper is out in NAR! 🥳
In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates.
Read:
academic.oup.com/nar/article-...
In collaboration with @saramaciasrna.bsky.social, we show DGCR8 haploinsufficiency disrupts pluripotency in hESC by affecting primate-specific miRNAs and TEs. Our findings highlight a co-evolved miRNA-TE network in primates.
Read:
academic.oup.com/nar/article-...
Reposted by Ayushi Rehman
Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms @fuxmanlab.bsky.social
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
March 27, 2025 at 4:30 AM
Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms @fuxmanlab.bsky.social
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Reposted by Ayushi Rehman
I’m also curating a preList with @prelights.bsky.social, so if you’re coming along to present a preprint then please send it in here: forms.gle/JYiTFj8iSUcT... (2/2)
Add your preprint to the Biologists @ 100 preList
The preLights conference reporter for Biologists @100, Jonathan Townson, is collating a preList that aims to capture all preprints being discussed at the meeting (either as part of the poster sessions...
forms.gle
March 24, 2025 at 9:07 AM
I’m also curating a preList with @prelights.bsky.social, so if you’re coming along to present a preprint then please send it in here: forms.gle/JYiTFj8iSUcT... (2/2)