Aaron Francis
@awfranci.bsky.social
PhD Student, Integrated Systems Biology (ISB) - University of Pittsburgh | Gottschalk Lab
Interest: Innate Immune Signaling | Macrophages | Signing Networks | Machine Learning | Mechanistic Modeling
Interest: Innate Immune Signaling | Macrophages | Signing Networks | Machine Learning | Mechanistic Modeling
Reposted by Aaron Francis
#InmunosKy #oncosky #clinicalResearch #Myeloidcells (macrophages, neutrophils, eosinophils) not only support the immune system in infections, they are also key in the response to cancer. But did you know that they can be allies or enemies depending on the context?
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
Myeloid effector cells in cancer
Schol et al. describe in this perspective the key role of myeloid effector cells in tumor control during successful immunotherapy. They also discuss myeloid cell tumor-rejecting functions, their intricate interactions with tumor-specific T cells, and highlight strategies to activate them for therapeutic applications.
www.cell.com
December 12, 2024 at 12:11 PM
#InmunosKy #oncosky #clinicalResearch #Myeloidcells (macrophages, neutrophils, eosinophils) not only support the immune system in infections, they are also key in the response to cancer. But did you know that they can be allies or enemies depending on the context?
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
Reposted by Aaron Francis
NiCo is out! Our new algorithm for spatial transcriptomics data analysis predicts the crosstalk of cell types co-localized in tissue niches and sheds light on signalling mediators and downstream effects of cell-cell interactions by inferring covarying gene programs.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 6, 2024 at 12:00 PM
NiCo is out! Our new algorithm for spatial transcriptomics data analysis predicts the crosstalk of cell types co-localized in tissue niches and sheds light on signalling mediators and downstream effects of cell-cell interactions by inferring covarying gene programs.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Aaron Francis
New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇
November 28, 2024 at 7:07 PM
New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇
Reposted by Aaron Francis
Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 27, 2024 at 8:11 PM
Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Aaron Francis
The diversification of methods for studying cell–cell interactions and communication
www.nature.com/articles/s41... in @natrevgenet.bsky.social
www.nature.com/articles/s41... in @natrevgenet.bsky.social
The diversification of methods for studying cell–cell interactions and communication - Nature Reviews Genetics
In this Review, the authors summarize recent progress in cell–cell interaction (CCI) research. They describe the recent evolution in computational tools that underpin CCI studies, discuss improve...
www.nature.com
November 25, 2024 at 5:45 PM
The diversification of methods for studying cell–cell interactions and communication
www.nature.com/articles/s41... in @natrevgenet.bsky.social
www.nature.com/articles/s41... in @natrevgenet.bsky.social