Arnab Chatterjee
@arnabchatterjee611.bsky.social
MS-PhD student at Indian Institute of Science (2019-2026).
#Cryo-electron microscopy. #Dutta_lab #mbu_iisc
#Cryo-electron microscopy. #Dutta_lab #mbu_iisc
Reposted by Arnab Chatterjee
OPUS-ET: Resolving Compositional and Conformational Heterogeneities of Biomolecules in Cryo-Electron Tomography www.biorxiv.org/content/10.1101/2025.11.21.688990v1 #cryoem
November 24, 2025 at 8:10 AM
OPUS-ET: Resolving Compositional and Conformational Heterogeneities of Biomolecules in Cryo-Electron Tomography www.biorxiv.org/content/10.1101/2025.11.21.688990v1 #cryoem
Reposted by Arnab Chatterjee
Structural insights into pre-pore intermediates of alpha-hemolysin in the lipidic environment pubmed.ncbi.nlm.nih.gov/40640160/ #cryoem
July 11, 2025 at 9:28 AM
Structural insights into pre-pore intermediates of alpha-hemolysin in the lipidic environment pubmed.ncbi.nlm.nih.gov/40640160/ #cryoem
A part of my PhD work is now published in Nat Comm, describing the oligomerization mechanism of α-HL/Hla in the lipidic environment, answering a long-standing question. Last month, I presented this work at the 3DEM Gordon Research Conferences in Maine, USA.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Structural insights into pre-pore intermediates of alpha-hemolysin in the lipidic environment - Nature Communications
Staphylococcus aureus secretes pore-forming toxins, such as α-hemolysin, which damage the cell membranes. Here the authors describe the cryo-EM structures of the α-hemolysin pore, and pre-pores in lip...
www.nature.com
July 10, 2025 at 2:13 PM
A part of my PhD work is now published in Nat Comm, describing the oligomerization mechanism of α-HL/Hla in the lipidic environment, answering a long-standing question. Last month, I presented this work at the 3DEM Gordon Research Conferences in Maine, USA.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Arnab Chatterjee
Cryo-EM reveals conformational variability in the SARS-CoV-2 spike protein RBD induced by two broadly neutralizing monoclonal antibodies pubmed.ncbi.nlm.nih.gov/40330036/ #cryoem
May 9, 2025 at 1:20 AM
Cryo-EM reveals conformational variability in the SARS-CoV-2 spike protein RBD induced by two broadly neutralizing monoclonal antibodies pubmed.ncbi.nlm.nih.gov/40330036/ #cryoem
Reposted by Arnab Chatterjee

🧬🎉Thrilled to share our new chromatin remodeling study! We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link: authors.elsevier.com/a/1l2ik3vVUP...
🧬🎉Thrilled to share our new chromatin remodeling study! We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link: authors.elsevier.com/a/1l2ik3vVUP...
May 6, 2025 at 3:08 PM

🧬🎉Thrilled to share our new chromatin remodeling study! We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link: authors.elsevier.com/a/1l2ik3vVUP...
🧬🎉Thrilled to share our new chromatin remodeling study! We reveal three states of human CHD1 and identify a novel "anchor element" that interacts with the acidic patch—conserved among remodelers. Our structures clarify mechanisms of remodeler recruitment! Link: authors.elsevier.com/a/1l2ik3vVUP...
Reposted by Arnab Chatterjee
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
April 6, 2025 at 9:45 AM
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
Reposted by Arnab Chatterjee
Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
April 11, 2025 at 8:35 AM
Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
🔗 Preprint here tinyurl.com/3a74uanv
Reposted by Arnab Chatterjee
Without SP2, HIV-1 fuses more slowly with target cells. We worked with Kräusslich and Müller labs @uniheidelberg.bsky.social,
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation - Nature
A study reports that the structural maturation of the matrix domain of the Gag protein of HIV-1 is induced by the proteolytic release and binding of the spacer peptide SP2.
www.nature.com
February 28, 2025 at 2:04 PM
Without SP2, HIV-1 fuses more slowly with target cells. We worked with Kräusslich and Müller labs @uniheidelberg.bsky.social,
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
Reposted by Arnab Chatterjee
Zhi Yang Tan & @shujuncai.bsky.social's comparative study of G0 (quiescent) and interphase fission yeast cells is out in @jcellsci.bsky.social doi.org/10.1242/jcs.263654. This study combines multiple cell-biological analyses with in situ cryo-ET. Raw data: www.ebi.ac.uk/empiar/EMPIAR-10339
March 4, 2025 at 5:30 PM
Zhi Yang Tan & @shujuncai.bsky.social's comparative study of G0 (quiescent) and interphase fission yeast cells is out in @jcellsci.bsky.social doi.org/10.1242/jcs.263654. This study combines multiple cell-biological analyses with in situ cryo-ET. Raw data: www.ebi.ac.uk/empiar/EMPIAR-10339