Ariel Levine
@ariellevine.bsky.social
Spinal cord and motor control scientist; PI at NINDS
@runewberg.bsky.social congrats Rune and team! This looks really cool
Neural manifolds that orchestrate walking and stopping https://www.biorxiv.org/content/10.1101/2025.11.08.687367v1
November 9, 2025 at 1:26 PM
@runewberg.bsky.social congrats Rune and team! This looks really cool
Reposted by Ariel Levine
🚨Job alert🚨
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
3 Postdoctoral Research Fellows
Champalimaud Foundation (Fundação D. Anna de Sommer Champalimaud e Dr.
euraxess.ec.europa.eu
November 4, 2025 at 5:11 PM
🚨Job alert🚨
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
The lab has up to *3 postdoc openings* for comp systems neuroscientists interested in describing and manipulating neural population dynamics mediating behaviour
This is part of a collaborative ARIA grant "4D precision control of cortical dynamics"
euraxess.ec.europa.eu/jobs/383909
Reposted by Ariel Levine
The latest work from our PRECISION Human Pain Center project is now up on @biorxivpreprint.bsky.social led by Katherin Gabriel and @oliviadavis.bsky.social with a huge contribution from @allanhpool.bsky.social's lab and, of course, the Southwest Transplant Alliance: www.biorxiv.org/content/10.1...
A molecular map of the human spinal dorsal and ventral horn defines arrangement of neuronal types and glial sex differences
The spinal cord is the gateway for sensory information from the body as it ascends to the brain, as well as a major motor output center of the nervous system. It is also a key location for sensory-mot...
www.biorxiv.org
November 1, 2025 at 12:10 PM
The latest work from our PRECISION Human Pain Center project is now up on @biorxivpreprint.bsky.social led by Katherin Gabriel and @oliviadavis.bsky.social with a huge contribution from @allanhpool.bsky.social's lab and, of course, the Southwest Transplant Alliance: www.biorxiv.org/content/10.1...
Reposted by Ariel Levine
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding
The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...
www.biorxiv.org
October 26, 2025 at 5:15 PM
Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
🧵👇
www.biorxiv.org/content/10.1...
Reposted by Ariel Levine
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity!
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
October 22, 2025 at 8:41 PM
🧠🌟🐭 Excited to share some of my postdoc work on the evolution of dexterity!
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
We compared deer mice evolved in forest vs prairie habitats. We found that forest mice have:
(1) more corticospinal neurons (CSNs)
(2) better hand dexterity
(3) more dexterous climbing, which is linked to CSN number🧵
Reposted by Ariel Levine
Our first preprint has been accepted for publication www.science.org/doi/10.1126/... !!
tldr: @ezeyulu00.bsky.social , @amartyapradhan.bsky.social , @dkoveal.bsky.social and I developed a method using injectable nanoparticles to turn mice into…constellations in motion. 🧵⤵️
tldr: @ezeyulu00.bsky.social , @amartyapradhan.bsky.social , @dkoveal.bsky.social and I developed a method using injectable nanoparticles to turn mice into…constellations in motion. 🧵⤵️
High-resolution in vivo kinematic tracking with customized injectable fluorescent nanoparticles
Injectable fluorescent nanoparticles were used to track positions on and inside of freely moving animals at high resolution.
www.science.org
October 2, 2025 at 7:45 PM
Our first preprint has been accepted for publication www.science.org/doi/10.1126/... !!
tldr: @ezeyulu00.bsky.social , @amartyapradhan.bsky.social , @dkoveal.bsky.social and I developed a method using injectable nanoparticles to turn mice into…constellations in motion. 🧵⤵️
tldr: @ezeyulu00.bsky.social , @amartyapradhan.bsky.social , @dkoveal.bsky.social and I developed a method using injectable nanoparticles to turn mice into…constellations in motion. 🧵⤵️
Sabbatical question - which activities do you keep up and which do you pause?
Eg reviewing new papers and grants, non-mentorship related service committee meetings, normal schedule of lab meetings…
Eg reviewing new papers and grants, non-mentorship related service committee meetings, normal schedule of lab meetings…
September 16, 2025 at 2:16 PM
Sabbatical question - which activities do you keep up and which do you pause?
Eg reviewing new papers and grants, non-mentorship related service committee meetings, normal schedule of lab meetings…
Eg reviewing new papers and grants, non-mentorship related service committee meetings, normal schedule of lab meetings…
Does anyone have favorite colors for color blind friendly fluorescence images on a black background where the overlap combinations of 3 colors are important?
Magenta/cyan/yellow overlaps are difficult to distinguish (lots of white)
Thank you!
Magenta/cyan/yellow overlaps are difficult to distinguish (lots of white)
Thank you!
September 11, 2025 at 5:11 PM
Does anyone have favorite colors for color blind friendly fluorescence images on a black background where the overlap combinations of 3 colors are important?
Magenta/cyan/yellow overlaps are difficult to distinguish (lots of white)
Thank you!
Magenta/cyan/yellow overlaps are difficult to distinguish (lots of white)
Thank you!
Reposted by Ariel Levine
Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social!
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
1/10
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
1/10
Compositional neural dynamics during reaching
The complex mechanics of the arm make the neural control of reaching inherently posture dependent. Because previous reaching studies confound reach direction with final posture, it remains unknown how...
www.biorxiv.org
September 6, 2025 at 1:12 PM
Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social!
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
1/10
We asked: How does the motor cortex account for arm posture when generating movement?
Paper 👉 www.biorxiv.org/content/10.1...
1/10
@petrznam.bsky.social this is so cool!
Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits https://www.biorxiv.org/content/10.1101/2025.07.16.665048v1
July 21, 2025 at 3:32 AM
@petrznam.bsky.social this is so cool!
Reposted by Ariel Levine
1/N
How do neural dynamics in motor cortex interact with those in subcortical networks to flexibly control movement? I’m beyond thrilled to share our work on this problem, led by Eric Kirk @eric-kirk.bsky.social with help from Kangjia Cai!
www.biorxiv.org/content/10.1...
How do neural dynamics in motor cortex interact with those in subcortical networks to flexibly control movement? I’m beyond thrilled to share our work on this problem, led by Eric Kirk @eric-kirk.bsky.social with help from Kangjia Cai!
www.biorxiv.org/content/10.1...
June 23, 2025 at 12:28 PM
1/N
How do neural dynamics in motor cortex interact with those in subcortical networks to flexibly control movement? I’m beyond thrilled to share our work on this problem, led by Eric Kirk @eric-kirk.bsky.social with help from Kangjia Cai!
www.biorxiv.org/content/10.1...
How do neural dynamics in motor cortex interact with those in subcortical networks to flexibly control movement? I’m beyond thrilled to share our work on this problem, led by Eric Kirk @eric-kirk.bsky.social with help from Kangjia Cai!
www.biorxiv.org/content/10.1...
Reposted by Ariel Levine
Paper is finally out on our experimentally-driven neuromechanical model to explain how spinal inhibition makes you do things faster! www.cell.com/cell-reports...
The spinal premotor network driving scratching flexor and extensor alternation
Yao et al. developed a neuromechanical model based on experimental perturbations,
aligning theory-predicted with genetically labeled cell types. This work highlights
the importance of inhibitory inter...
www.cell.com
June 18, 2025 at 2:04 PM
Paper is finally out on our experimentally-driven neuromechanical model to explain how spinal inhibition makes you do things faster! www.cell.com/cell-reports...
Reposted by Ariel Levine
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
June 12, 2025 at 12:09 PM
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
Reposted by Ariel Levine
Despite some ups and downs at NIH, we do have an open position for a postbac and are considering candidates.
Our work is at the intersection of neuroscience and AI, and we aim to understand how the brain's densely connected recurrent networks operate. 🧪
Our work is at the intersection of neuroscience and AI, and we aim to understand how the brain's densely connected recurrent networks operate. 🧪
May 15, 2025 at 9:02 PM
Despite some ups and downs at NIH, we do have an open position for a postbac and are considering candidates.
Our work is at the intersection of neuroscience and AI, and we aim to understand how the brain's densely connected recurrent networks operate. 🧪
Our work is at the intersection of neuroscience and AI, and we aim to understand how the brain's densely connected recurrent networks operate. 🧪
Todd is a fantastic scientist, mentor, colleague and friend. Highly recommend!!
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
www.training.nih.gov
April 29, 2025 at 6:24 PM
Todd is a fantastic scientist, mentor, colleague and friend. Highly recommend!!
Reposted by Ariel Levine
Our PhD student Louis Romette is optimizing long-term live-cell imaging. He just casually dropped this 65-hour movie of a growing neuron (div 3 to 6) with knocked-in actin 🔥🕶️ #realtimemicroscopy
April 17, 2025 at 1:30 PM
Our PhD student Louis Romette is optimizing long-term live-cell imaging. He just casually dropped this 65-hour movie of a growing neuron (div 3 to 6) with knocked-in actin 🔥🕶️ #realtimemicroscopy
Reposted by Ariel Levine
REPOSTING this here just to officially leave "the other place"
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Stretch-induced endogenous electric fields drive directed collective cell migration in vivo - Nature Materials
Electric fields guide collective cell migration in developing embryos of Xenopus laevis via a voltage-sensitive phosphatase.
nature.com
April 7, 2025 at 9:46 AM
REPOSTING this here just to officially leave "the other place"
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social
nature.com/articles/s41...
Reposted by Ariel Levine
Excited to share our new pre-print on bioRxiv, in which we reveal that feedback-driven motor corrections are encoded in small, previously missed neural signals.
April 7, 2025 at 2:55 PM
Excited to share our new pre-print on bioRxiv, in which we reveal that feedback-driven motor corrections are encoded in small, previously missed neural signals.
What an elegant new assay for natural mouse behavior! Love this
New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, @liamebrowne.bsky.social and Rob Brownstone.
Ethologically relevant behavioural assay for investigating reach and grasp kinematics during whole-body motor control in mice https://www.biorxiv.org/content/10.1101/2025.04.04.647225v1
April 6, 2025 at 4:34 PM
What an elegant new assay for natural mouse behavior! Love this
Reposted by Ariel Levine
Igor Siwanowicz of @hhmijanelia.bsky.social captured these photos of pollen grains on the sigma of a morning glory flower. This is part of the early stage in creating a seed, it might also be the reason why you can’t stop sneezing!
March 25, 2025 at 5:36 PM
Igor Siwanowicz of @hhmijanelia.bsky.social captured these photos of pollen grains on the sigma of a morning glory flower. This is part of the early stage in creating a seed, it might also be the reason why you can’t stop sneezing!
Reposted by Ariel Levine
Please register for this amazing meeting! Applications for this meeting must be submitted by June 8, 2025
March 20, 2025 at 4:18 PM
Please register for this amazing meeting! Applications for this meeting must be submitted by June 8, 2025
Reposted by Ariel Levine
Despite all of *waves around*, the Sheahan Lab is putting one foot in front of the other and is looking for a research technician. A great position for someone interested in gaining more neuroscience experience in itch & pain before applying for grad/med school: shorturl.at/DW3fU 🧠 #PainResearch
Research Technologist I
Medical College of Wisconsin - Research Technologist I - Milwaukee WI 53201
shorturl.at
March 17, 2025 at 6:13 PM
Despite all of *waves around*, the Sheahan Lab is putting one foot in front of the other and is looking for a research technician. A great position for someone interested in gaining more neuroscience experience in itch & pain before applying for grad/med school: shorturl.at/DW3fU 🧠 #PainResearch
Gorgeous image and a wonderful thread from @rbrianroome.bsky.social on our new work 🥳
Check out my postdoc work at Ariel Levine’s lab, hot and fresh, describing how you build a dorsal horn!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 17, 2025 at 4:30 PM
Gorgeous image and a wonderful thread from @rbrianroome.bsky.social on our new work 🥳
And science continues… check out our new work led by @rbrianroome.bsky.social
Ontogeny of the spinal cord dorsal horn https://www.biorxiv.org/content/10.1101/2025.03.14.643370v1
March 16, 2025 at 3:01 PM
And science continues… check out our new work led by @rbrianroome.bsky.social
Reposted by Ariel Levine
Registration started for the Janelia meeting on spinal cord and brainstem circuits for sensorimotor adaptation across species. Spinal cord is more than a hub, it does supercomputing!
www.janelia.org/you-janelia/...
www.janelia.org/you-janelia/...
Computing Cords: Sensorimotor Control by Nerve Cord Circuits Across Species
Organizers Salil Bidaye, Max Planck Florida Institute for Neuroscience Ansgar Büschges, University of Cologne Graziana Gatto, University of Cologne Abdel El Manira, Karolinska Institutet Julie
www.janelia.org
February 26, 2025 at 8:29 AM
Registration started for the Janelia meeting on spinal cord and brainstem circuits for sensorimotor adaptation across species. Spinal cord is more than a hub, it does supercomputing!
www.janelia.org/you-janelia/...
www.janelia.org/you-janelia/...