Jyot Antani
@antanij.bsky.social
https://antanij.netlify.app/
Microscopy of bacteria and their viruses.
Postdoc at Yale University @paulturnerlab.bsky.social. Phage researcher, biotech enthusiast.
Research Facilitator at Optical Microscopy and Imaging in Biomedical Sciences (MBL, Woods H
Microscopy of bacteria and their viruses.
Postdoc at Yale University @paulturnerlab.bsky.social. Phage researcher, biotech enthusiast.
Research Facilitator at Optical Microscopy and Imaging in Biomedical Sciences (MBL, Woods H
Congratulations Nanami! Glad to see this work published!
Published in Current Biology! P. aeruginosa can use its filamentous phage to inhibit competitors but high phage production is susceptible to cheater miniphage invasion. Subsequent phage tragedy of the commons can lower bacteria and phage fitness. Link: authors.elsevier.com/c/1lt5I3QW8S...
Preprint out! Bacteria w/ hyper-replicative filamentous phage lead to overnight emergence of cheater phages. Bacteria w/ both phages can outcompete wildtype, then rapidly lose phage via a phage Tragedy of the Commons
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
October 12, 2025 at 2:56 PM
Congratulations Nanami! Glad to see this work published!
Yay Cathy!!!
Very happy to share that I will be starting as an Assistant Professor in the department of Biological Sciences at the University of South Carolina in January! My group will be working on environmental phage ecology and evolution, and I am recruiting for the upcoming year (more info below).
October 8, 2025 at 5:21 PM
Yay Cathy!!!
Reposted by Jyot Antani
Happy to see this paper finally out in @pnas.org!
#phage #microbiology #MicroSky #VirEvol 🦠 🧫 🔬
Gift link: www.pnas.org/eprint/YYDZ9...
#phage #microbiology #MicroSky #VirEvol 🦠 🧫 🔬
Gift link: www.pnas.org/eprint/YYDZ9...
September 8, 2025 at 7:51 PM
Happy to see this paper finally out in @pnas.org!
#phage #microbiology #MicroSky #VirEvol 🦠 🧫 🔬
Gift link: www.pnas.org/eprint/YYDZ9...
#phage #microbiology #MicroSky #VirEvol 🦠 🧫 🔬
Gift link: www.pnas.org/eprint/YYDZ9...
Reposted by Jyot Antani
We're gearing up for #OMIBS2025
Getting stuff ready for the participants' arrival. The course kicks off tonight!
Getting stuff ready for the participants' arrival. The course kicks off tonight!
August 12, 2025 at 4:07 PM
We're gearing up for #OMIBS2025
Getting stuff ready for the participants' arrival. The course kicks off tonight!
Getting stuff ready for the participants' arrival. The course kicks off tonight!
Ovaries and stigma of Mimulus plants, stained with Aniline blue.
Max Z projections from just widefield fluorescence images! 💙🔬🤩
#microscopy with Henry Arenas-Castro @jenncoughlan.bsky.social lab
Max Z projections from just widefield fluorescence images! 💙🔬🤩
#microscopy with Henry Arenas-Castro @jenncoughlan.bsky.social lab
June 24, 2025 at 4:08 PM
Ovaries and stigma of Mimulus plants, stained with Aniline blue.
Max Z projections from just widefield fluorescence images! 💙🔬🤩
#microscopy with Henry Arenas-Castro @jenncoughlan.bsky.social lab
Max Z projections from just widefield fluorescence images! 💙🔬🤩
#microscopy with Henry Arenas-Castro @jenncoughlan.bsky.social lab
Going for the mini plushie at @asm.org #ASMicrobe 🦠🔬
June 22, 2025 at 9:54 PM
Going for the mini plushie at @asm.org #ASMicrobe 🦠🔬
Know Your Worth: Salary Data that Defends Your Value
@asm.org ASM Studio
#ASMicrobe #ASMicrobe2025
asm.org/articles/sal...
@asm.org ASM Studio
#ASMicrobe #ASMicrobe2025
asm.org/articles/sal...
June 21, 2025 at 10:50 PM
Know Your Worth: Salary Data that Defends Your Value
@asm.org ASM Studio
#ASMicrobe #ASMicrobe2025
asm.org/articles/sal...
@asm.org ASM Studio
#ASMicrobe #ASMicrobe2025
asm.org/articles/sal...
Reposted by Jyot Antani
Come check out my poster tomorrow at #ASMicrobe in the E&EB section!
We found that repressor mutations in Pf prophages sparked a coevolutionary dynamic that resulted in loss of twitch motility and susceptibility to virulent pilus-targeting phage.
Would love to chat about all things phage :).
We found that repressor mutations in Pf prophages sparked a coevolutionary dynamic that resulted in loss of twitch motility and susceptibility to virulent pilus-targeting phage.
Would love to chat about all things phage :).
Turner Lab representation at #ASMicrobe #ASMicrobe2025
(3/5)
Grad student @noahhoupt.bsky.social will present the story of experimentally evolving a Pseudomonas lab strain for 150 generations over 1000 days. Spoiler alerts: #prophages are important! 🦠📊
#evolution
(3/5)
Grad student @noahhoupt.bsky.social will present the story of experimentally evolving a Pseudomonas lab strain for 150 generations over 1000 days. Spoiler alerts: #prophages are important! 🦠📊
#evolution
June 20, 2025 at 7:06 PM
Come check out my poster tomorrow at #ASMicrobe in the E&EB section!
We found that repressor mutations in Pf prophages sparked a coevolutionary dynamic that resulted in loss of twitch motility and susceptibility to virulent pilus-targeting phage.
Would love to chat about all things phage :).
We found that repressor mutations in Pf prophages sparked a coevolutionary dynamic that resulted in loss of twitch motility and susceptibility to virulent pilus-targeting phage.
Would love to chat about all things phage :).
Reposted by Jyot Antani
For #ASMicrobe folks - looking forward to a busy phage day on Sunday!
Turner Lab representation at #ASMicrobe #ASMicrobe2025
(4/5)
Current postdoc, soon-to-be-PI @cathyhernandez.bsky.social is presenting a poster on the involvement of prophages in thermal ecology of marine microbes 🌊🦠
She is also convening a session on #prophages and giving a rapid fire talk! 🔥
(4/5)
Current postdoc, soon-to-be-PI @cathyhernandez.bsky.social is presenting a poster on the involvement of prophages in thermal ecology of marine microbes 🌊🦠
She is also convening a session on #prophages and giving a rapid fire talk! 🔥
June 20, 2025 at 7:06 PM
For #ASMicrobe folks - looking forward to a busy phage day on Sunday!
June 20, 2025 at 6:29 PM
Turner Lab representation at #ASMicrobe #ASMicrobe2025
(5/5)
Associate Research Scientist @antanij.bsky.social is telling a story about multidimensional measurements (including high-throughput adsorption assays) of phage-bacteria interactions #microscopy 🔬
(5/5)
Associate Research Scientist @antanij.bsky.social is telling a story about multidimensional measurements (including high-throughput adsorption assays) of phage-bacteria interactions #microscopy 🔬
June 20, 2025 at 5:04 PM
Reposted by Jyot Antani
Phage-Assisted Evolution of Allosteric Protein Switches https://www.biorxiv.org/content/10.1101/2025.06.12.659331v1
June 13, 2025 at 6:03 AM
Phage-Assisted Evolution of Allosteric Protein Switches https://www.biorxiv.org/content/10.1101/2025.06.12.659331v1
The human body is chock full of phages, from the skin to the gut. What role does the phageome have in health and disease? Watch Microbial Minutes for the story! www.youtube.com/watch?v=5PyM...
The Phageome’s Role in Health and Disease
YouTube video by American Society for Microbiology
www.youtube.com
June 12, 2025 at 7:52 PM
*High-school level summary article*
Wrote a piece describing our recent paper @paulturnerlab.bsky.social to a high-school educated audience. #phagesky #microsky
Reach out if you want to do the same for your recent paper. It's super fun!
www.journaloflifesciences.org/archives/156...
Wrote a piece describing our recent paper @paulturnerlab.bsky.social to a high-school educated audience. #phagesky #microsky
Reach out if you want to do the same for your recent paper. It's super fun!
www.journaloflifesciences.org/archives/156...
June 6, 2025 at 1:19 PM
*High-school level summary article*
Wrote a piece describing our recent paper @paulturnerlab.bsky.social to a high-school educated audience. #phagesky #microsky
Reach out if you want to do the same for your recent paper. It's super fun!
www.journaloflifesciences.org/archives/156...
Wrote a piece describing our recent paper @paulturnerlab.bsky.social to a high-school educated audience. #phagesky #microsky
Reach out if you want to do the same for your recent paper. It's super fun!
www.journaloflifesciences.org/archives/156...
Reposted by Jyot Antani
Hurray, it is finally out! Meet bacteriophage Bxb1 - the subject of my first full-phage cryo-EM study. My structures are beautifully complemented by the Park Lab’s cryo-ET analysis, shedding light on mycobacteriophage structural changes during infection.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Structure and infection dynamics of mycobacteriophage Bxb1
Mycobacteriophage Bxb1 is a well-characterized virus of Mycobacterium smegmatis with double-stranded DNA and a long, flexible tail. Mycobacteriophages…
www.sciencedirect.com
April 16, 2025 at 12:50 PM
Hurray, it is finally out! Meet bacteriophage Bxb1 - the subject of my first full-phage cryo-EM study. My structures are beautifully complemented by the Park Lab’s cryo-ET analysis, shedding light on mycobacteriophage structural changes during infection.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Our latest preprint just dropped @paulturnerlab.bsky.social
We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance!
www.biorxiv.org/content/10.1...
We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance!
www.biorxiv.org/content/10.1...
May 16, 2025 at 12:28 PM
Our latest preprint just dropped @paulturnerlab.bsky.social
We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance!
www.biorxiv.org/content/10.1...
We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance!
www.biorxiv.org/content/10.1...
(1/3)
extension *really* useful in research after a long time! (possibly after Google Scholar Button)
AI outline may come in handy at some point (my mind's jury is out on that), but...
chromewebstore.google.com/detail/googl...
extension *really* useful in research after a long time! (possibly after Google Scholar Button)
AI outline may come in handy at some point (my mind's jury is out on that), but...
chromewebstore.google.com/detail/googl...
Google Scholar PDF Reader - Chrome Web Store
Supercharge your paper reading: follow references, skim outline, jump to figures, cite and save.
chromewebstore.google.com
May 16, 2025 at 12:22 PM
(1/3)
extension *really* useful in research after a long time! (possibly after Google Scholar Button)
AI outline may come in handy at some point (my mind's jury is out on that), but...
chromewebstore.google.com/detail/googl...
extension *really* useful in research after a long time! (possibly after Google Scholar Button)
AI outline may come in handy at some point (my mind's jury is out on that), but...
chromewebstore.google.com/detail/googl...
Latest paper drop from Yale Phage Center @paulturnerlab.bsky.social
Yale researchers have made a breakthrough in fighting drug-resistant infections in cystic fibrosis with inhaled bacteriophage therapy - offering new hope against antimicrobial resistance.
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis - Nature Medicine
A novel personalized phage therapy strategy that selects phages for a predicted evolutionary trade-off may represent a viable alternative approach for the treatment of antimicrobial-resistant bacteria...
www.nature.com
May 8, 2025 at 2:04 AM
Latest paper drop from Yale Phage Center @paulturnerlab.bsky.social
Very cool thread!
Very excited to share a manuscript at the heart of my PhD! We added an RNA-memory device (RAM) to phage P1 to identify transduction hosts in synthetic and wastewater microbial communities in high throughput. Also, I am on the post-doc market, so please reach out if interested! 1/6
t.ly/a8k9O
t.ly/a8k9O
Cross-order detection of bacteriophage transduction in communities using ribosomal RNA barcoding
Bacteriophages (phages) facilitate gene transfer and microbial evolution in all ecosystems and have applications as tools for engineering microbiomes and as antimicrobials. Historic efforts to map pha...
t.ly
May 8, 2025 at 1:53 AM
Very cool thread!
Reposted by Jyot Antani
Microscopic phage adsorption assay: High-throughput quantification of virus particle attachment to host bacterial cells.
DOI: 10.1073/pnas.2410905121
https://pubmed.ncbi.nlm.nih.gov/39700139/
DOI: 10.1073/pnas.2410905121
https://pubmed.ncbi.nlm.nih.gov/39700139/
Microscopic phage adsorption assay: High-throughput quantification of virus particle attachment to host bacterial cells - PubMed
Phages, viruses of bacteria, play a pivotal role in Earth's biosphere and hold great promise as therapeutic and diagnostic tools in combating infectious diseases. Attachment of phages to bacterial cells is a crucial initial step of the interaction. The classic assay to quantify the dynamics of phage …
pubmed.ncbi.nlm.nih.gov
February 20, 2025 at 9:40 PM
Microscopic phage adsorption assay: High-throughput quantification of virus particle attachment to host bacterial cells.
DOI: 10.1073/pnas.2410905121
https://pubmed.ncbi.nlm.nih.gov/39700139/
DOI: 10.1073/pnas.2410905121
https://pubmed.ncbi.nlm.nih.gov/39700139/
Reposted by Jyot Antani
Please join us in welcoming UBC-Zoology’s newest Assistant Professor: Asher Leeks! @asherleeks.bsky.social
Today is Asher’s first day as an Assistant Professor of Evolution in the Department of Zoology and the @ubcbiodiversity.bsky.social @science.ubc.ca
Welcome Asher! 🙌🏽
asherleeks.com
Today is Asher’s first day as an Assistant Professor of Evolution in the Department of Zoology and the @ubcbiodiversity.bsky.social @science.ubc.ca
Welcome Asher! 🙌🏽
asherleeks.com
March 3, 2025 at 7:01 PM
Please join us in welcoming UBC-Zoology’s newest Assistant Professor: Asher Leeks! @asherleeks.bsky.social
Today is Asher’s first day as an Assistant Professor of Evolution in the Department of Zoology and the @ubcbiodiversity.bsky.social @science.ubc.ca
Welcome Asher! 🙌🏽
asherleeks.com
Today is Asher’s first day as an Assistant Professor of Evolution in the Department of Zoology and the @ubcbiodiversity.bsky.social @science.ubc.ca
Welcome Asher! 🙌🏽
asherleeks.com
Reposted by Jyot Antani
Preprint out! Bacteria w/ hyper-replicative filamentous phage lead to overnight emergence of cheater phages. Bacteria w/ both phages can outcompete wildtype, then rapidly lose phage via a phage Tragedy of the Commons
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
Filamentous cheater phages drive bacterial and phage populations to lower fitness
Many bacteria carry phage genome(s) in their chromosome (i.e., prophage), and this intertwines the fitness of the bacterium and the phage. Most Pseudomonas aeruginosa strains carry filamentous phages ...
www.biorxiv.org
April 2, 2025 at 12:41 PM
Preprint out! Bacteria w/ hyper-replicative filamentous phage lead to overnight emergence of cheater phages. Bacteria w/ both phages can outcompete wildtype, then rapidly lose phage via a phage Tragedy of the Commons
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
@shellyscrib.bsky.social @vscooper.micropopbio.org www.biorxiv.org/content/10.1...
YaleNews @yale.edu covered our recent paper on measuring virus attachment 🦠🔬🤩
@paulturnerlab.bsky.social @emonetlab.bsky.social
news.yale.edu/2025/04/15/n...
#MicroSky #PhageSky #Microscopy #Fluorescence
@paulturnerlab.bsky.social @emonetlab.bsky.social
news.yale.edu/2025/04/15/n...
#MicroSky #PhageSky #Microscopy #Fluorescence
New tool offers insights into virus-cell interactions
A method developed by Yale scientists helps reveal how antibacterial agents interact with their host cells — a process that could boost a host of applications that benefit society.
news.yale.edu
April 17, 2025 at 1:35 PM
YaleNews @yale.edu covered our recent paper on measuring virus attachment 🦠🔬🤩
@paulturnerlab.bsky.social @emonetlab.bsky.social
news.yale.edu/2025/04/15/n...
#MicroSky #PhageSky #Microscopy #Fluorescence
@paulturnerlab.bsky.social @emonetlab.bsky.social
news.yale.edu/2025/04/15/n...
#MicroSky #PhageSky #Microscopy #Fluorescence
Super cool work modernizing phage biology! #phagesky 💧🔬🦠
www.biorxiv.org/content/10.1...
Digital Phage Biology in Droplet by Givelet et al.
Digital Phage Biology in Droplet by Givelet et al.
Digital Phage Biology in Droplets
Since their discovery, bacteriophages – viruses that infect bacteria – have been an invaluable source of insight for molecular biology and have provided a plethora of molecular components for biotechn...
www.biorxiv.org
January 26, 2025 at 3:05 PM
Super cool work modernizing phage biology! #phagesky 💧🔬🦠
My mehndi (henna tattoo) at close cousin's wedding.
I asked the tattoo-artist to draw the podovirus where the genome is cousin's wedding logo.
#phagesky
I asked the tattoo-artist to draw the podovirus where the genome is cousin's wedding logo.
#phagesky
January 23, 2025 at 10:36 AM
My mehndi (henna tattoo) at close cousin's wedding.
I asked the tattoo-artist to draw the podovirus where the genome is cousin's wedding logo.
#phagesky
I asked the tattoo-artist to draw the podovirus where the genome is cousin's wedding logo.
#phagesky