Andrew Leduc
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andrewleduc.bsky.social
Andrew Leduc
@andrewleduc.bsky.social
Post-doc Slavov Lab
https://andrew-leduc.github.io/
Studying how variation in protein half-life
leads to variation in protein levels
Also the cells are sorted by growth rate so idk some meaning to the ordering
September 24, 2025 at 4:07 PM
Yeah its not great, it just made comparisons of the different modalities a bit easier to visualize than when we plotted a scatter but will revisit. Thanks for feedback!
September 24, 2025 at 2:06 PM
I have admittedly been on the non-PI side of this only to realize how true this must be after receiving a blank stare 😅
September 23, 2025 at 4:20 PM
Trust me, its better than whatever harm "doing their jobs" will cause...
August 21, 2025 at 3:51 PM
What about predictions that involve many proteins interacting together?
July 5, 2025 at 6:33 PM
Yeah, for sure not true but also probably looking under the lamp post effect as well!
July 3, 2025 at 5:58 PM
Once you have a certain level of aggregation, it does become hard to imagine removing it easily. What if the aggregate is too large to fit in a lysosome? I dont know I guess what the size scales are
June 22, 2025 at 2:14 PM
What do you use to measure blood sugar?
June 17, 2025 at 2:18 PM
All ideas != create equal 😅
June 10, 2025 at 2:50 PM
Reposted by Andrew Leduc
Yes, testis are special but not the only tissues in which we see substantial discrepancies.

We have seen them in all tissues that we have analyzed, and @andrewleduc.bsky.social has even more compelling examples from mouse trachea ... soon to be published!
June 7, 2025 at 5:11 PM