If you’re around St. Louis and interested in learning about Lewy body dementias (Parkinson disease dementia & Dementia with Lewy bodies), join us on Nov. 6.

Riding back to Honolulu airport after attending & presenting at the #MDSCongress. Charles, the Lyft driver, has a theme for every 2 months of the year. This is Oct-Nov Halloween Mario theme. He also takes it upon himself to teach passengers something about Hawaii. Great conference & great Lyft ride!

Great sessions in @movedisorder.bsky.social congress in #Honolulu with outstanding speakers and excellent organization. I must say, however, that the poster session is a disaster. The traditional way works much better. 1/3

This is an important study that agrees with previous reports suggesting gabapentin & pregabalin use as a risk factor for cognitive impairment and dementia. My only major concern is that spinal and orthopedic surgery or surgery in general was not used in the propensity score matching procedure. 1/5

A balanced and well-researched article on clozapine for Parkinson disease psychosis in light of the new FDA removal of required blood count monitoring.

doi.org/10.1002/mds....

Amazing work led by our collaborator and brilliant PhD student Jake Chernicky.

I just signed the open letter in support of the Bethesda Declaration

Our review 'Update on the Treatment of Autonomic Disorders' just got published. We discuss non-pharmacological, pharmacological, and neuromodulatory and device options for autonomic disorders in a very clinic-oriented way. This is an important topic for neurologists and primary care physicians.

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...

Mind-blowing case of the day. This guy w/ Parkinson's has a left leg amputation. Later he develops phantom dystonia in the region of the missing limb? Eid, Rodrigo, and Norris teach us about the phenomenon through a case they published in the Movement Disorders Clinical Practice Journal.

Our report on PD-Related Phantom Dystonia in an Amputated Limb just got published in @mdcp-journal.bsky.social. Fascinating phenomenon; to my knowledge, never been reported before though other reported phenomena e.g. virtual dystonia are possibly related.
PDF: onlinelibrary.wiley.com/share/author...

Great guidance for caregivers; particularly applicable to Alzheimer disease

Excellent article! I particularly like the last paragraph.

Like most, I’m worried about the course of action the new US administration is taking towards scientific activity and healthcare. However, I don’t think the appropriate long-term response is to ensure administrations take a different course in the future. 1/2

Led by Dr. Erika Weil, we publish a report in Neurology highlighting a patient with striatal ePVSs (beautifully captured on 7T MRI) likely responsible for her impaired executive function as suggested by reduced striatal & normal cortical metabolism (FDG PET) and neg Aβ PET.
doi.org/10.1212/WNL....

A very interesting article showing how the unstable HD alleles cause striatal projection neuronal degeneration by the process of somatic CAG repeat expansion beyond 150 repeats.

www.cell.com/cell/fulltex...

🚨Interested in Dystonia?🚨
@braincircuits.bsky.social

GPi DBS for dystonia is effective.

More recently, STN DBS has been investigated, as an alternative.

In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks…

www.pnas.org/doi/10.1073/...

Our chapter 'Therapeutic Strategies in Neurodegenerative Diseases' in 'Neuroimmune Pharmacology and Therapeutics' is now published. It highlights gene therapy, cell therapy and immunotherapy as key strategies under investigation and summarizes clinically available therapies. Link: rdcu.be/d4YQq