@aletortorici.bsky.social
Structural virologist who also loves sports
@veeslerlab.bsky.social
@veeslerlab.bsky.social
In case you did not read it yet, check how in-host evolution of feline coronavirus is leading to a highly pathogenic disease in cats.
Our paper describing how in-host evolution of a recently emerged, highly pathogenic coronavirus modulates entry into cells, membrane fusion and likely pathogenicity has now been published in its peer-reviewed form!
Led by Ale Tortorici!
@hhmi.org
www.nature.com/articles/s41...
Led by Ale Tortorici!
@hhmi.org
www.nature.com/articles/s41...
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics - Nature
The molecular mechanisms of cell entry for the recently identified highly pathogenic feline coronavirus FCoV-23 are characterized in detail.
www.nature.com
November 19, 2025 at 4:36 PM
In case you did not read it yet, check how in-host evolution of feline coronavirus is leading to a highly pathogenic disease in cats.
Reposted
Delighted to share the peer-reviewed version of our article describing a prefusion-stabilized MARV GP vaccine immunogen and a best-in-class MARV neutralizing and protective antibody!
Led by @aminaddetia.bsky.social with @virbiotechnology.bsky.social
@hhmi.org
www.nature.com/articles/s41...
Led by @aminaddetia.bsky.social with @virbiotechnology.bsky.social
@hhmi.org
www.nature.com/articles/s41...
Potent neutralization of Marburg virus by a vaccine-elicited antibody - Nature
Nature - Potent neutralization of Marburg virus by a vaccine-elicited antibody
www.nature.com
November 12, 2025 at 4:20 PM
Delighted to share the peer-reviewed version of our article describing a prefusion-stabilized MARV GP vaccine immunogen and a best-in-class MARV neutralizing and protective antibody!
Led by @aminaddetia.bsky.social with @virbiotechnology.bsky.social
@hhmi.org
www.nature.com/articles/s41...
Led by @aminaddetia.bsky.social with @virbiotechnology.bsky.social
@hhmi.org
www.nature.com/articles/s41...
Reposted
The heath benefits of multilingualism appear to be far beyond prior expectations
erictopol.substack.com/p/multilingu...
erictopol.substack.com/p/multilingu...
Multilingualism and Extending Healthspan
Evidence for a new independent lifestyle factor linked to healthy aging
erictopol.substack.com
November 10, 2025 at 4:08 PM
The heath benefits of multilingualism appear to be far beyond prior expectations
erictopol.substack.com/p/multilingu...
erictopol.substack.com/p/multilingu...
Reposted
Delighted to share our most recent work on designing broadly protective sarbecovirus vaccines and defining the path forward for other coronaviruses.
Led by @aminaddetia.bsky.social
@hhmi.org
www.biorxiv.org/content/10.1...
Led by @aminaddetia.bsky.social
@hhmi.org
www.biorxiv.org/content/10.1...
Phylogeny-driven design of broadly protective sarbecovirus receptor-binding domain nanoparticle vaccines
Vaccines against emerging SARS-CoV-2 variants and sarbecoviruses with pandemic potential must elicit a robust humoral immune response in a population imprinted with the SARS-CoV-2 spike (S) protein. H...
www.biorxiv.org
May 14, 2025 at 2:21 PM
Delighted to share our most recent work on designing broadly protective sarbecovirus vaccines and defining the path forward for other coronaviruses.
Led by @aminaddetia.bsky.social
@hhmi.org
www.biorxiv.org/content/10.1...
Led by @aminaddetia.bsky.social
@hhmi.org
www.biorxiv.org/content/10.1...
Reposted
Our latest work on #COVID immunity and imprinting in humans.
Led by Ale Tortorici and Kaiti Sprouse with @aminaddetia.bsky.social and several others!
www.biorxiv.org/content/10.1...
Led by Ale Tortorici and Kaiti Sprouse with @aminaddetia.bsky.social and several others!
www.biorxiv.org/content/10.1...
Repeated COVID-19 vaccine boosters elicit variant-specific memory B cells in humans
The first exposure to a pathogen or an antigen profoundly impacts immune responses upon subsequent encounter with related pathogens. This immune imprinting explains that infection or vaccination with ...
www.biorxiv.org
October 21, 2025 at 3:42 AM
Our latest work on #COVID immunity and imprinting in humans.
Led by Ale Tortorici and Kaiti Sprouse with @aminaddetia.bsky.social and several others!
www.biorxiv.org/content/10.1...
Led by Ale Tortorici and Kaiti Sprouse with @aminaddetia.bsky.social and several others!
www.biorxiv.org/content/10.1...