Alessandro Gozzo
alessogozzo.bsky.social
Alessandro Gozzo
@alessogozzo.bsky.social
👨‍🔬PhD Student @ost_lab

🔬Trying to solve my daddy issues one small RNA at a time!🧬
Because why just inherit the family drama when you can research it too!
Reposted by Alessandro Gozzo
Our story from @oestlab.bsky.social studying the levels of small RNA (sRNA) in sperm from IVF is finally out in @natcomms.nature.com! We wanted to understand whether there are specific sperm sRNA important for male fertility, and it turns out there are 🤯
rdcu.be/eET51
Small RNA in sperm–Paternal contributions to human embryo development
Nature Communications - Sperm delivers not only the paternal genome but also regulatory sRNAs. Here they show that sRNAs, including miRNAs and Y-RNAs, correlate with sperm concentration,...
rdcu.be
September 8, 2025 at 12:18 PM
Reposted by Alessandro Gozzo
Dear president@harvard.edu, dear gaudet@mcb.harvard.edu,
to learn more about the importance of #Drosophila and crucial role of @flybase.bsky.social, and how it gave rise to at least 9 Nobel laureates in Physiology and Medicine, please see this link:
droso4schools.wordpress.com/why-fly/
August 25, 2025 at 9:36 AM
Reposted by Alessandro Gozzo
New from the lab led by @natrigg.bsky.social. We started by characterizing mRNA in sperm, EVs, and the epithelium across epididymal transit. This revealed evidence that sperm acquire specific mRNAs through fusion with epididymal EVs, which we further established with in vitro co-incubation assays
Epididymal extracellular vesicles harbor and convey mRNA to sperm for transfer to zygotes https://www.biorxiv.org/content/10.1101/2025.08.18.670952v1
August 23, 2025 at 6:30 PM
Reposted by Alessandro Gozzo
Very nice resources for arguing that studying flies is a good investment
Dear GenZ members of the #Drosophila community! You are needed to make cool fly research viral in your social media world! As a boomer I do not understand that sphere, but I can consult and contribute our enormous fund of outreach resources: droso4public.wordpress.com. Please, get in contact!
(no title)
droso4public is a central resource store supporting science communication and advocacy for Drosophila
droso4public.wordpress.com
August 25, 2025 at 10:43 PM
Reposted by Alessandro Gozzo
MassLive.com recently interviewed several Harvard FlyBase people and wrote this news article about the importance of FlyBase: tinyurl.com/4chpts9f
Why a database of bug genes could be one of Trump’s most devastating cuts at Harvard
FlyBase, the world's only fruit fly database, is in the crosshairs of Trump's attack on Harvard. Here's why it could matter for your health.
tinyurl.com
June 25, 2025 at 8:31 PM
I attended Epichrome for the first time as a bachelor student in 2021. Yesterday, I presented our latest research on sperm-borne mitochondrial small RNAs and their role in intergenerational metabolic responses at Epichrome in Stockholm! Exciting times, looking forward to what´s to come!

@ostlab
June 13, 2025 at 6:22 AM
Reposted by Alessandro Gozzo
We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...
June 3, 2025 at 9:17 PM
Reposted by Alessandro Gozzo
Our new paper is out@ScienceAdvances👇
www.science.org/doi/10.1126/...
🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells.
🔍 @katsuminami.bsky.social et al. have developed a chromatin behavior atlas within the nucleus. 1/2
March 29, 2025 at 1:06 AM
Reposted by Alessandro Gozzo
Can a father's health before conception shape future generations?

In our latest episode, Dr. Raffaele Teperino from @epihmgu.bsky.social unpacks the science behind paternal effects, epigenetics, and metabolic disruption.

Listen now: activemotif.com/podcasts-raf...
#Epigenetics #SciencePodcast
May 9, 2025 at 7:52 AM
Reposted by Alessandro Gozzo
Clearly, my first ever Bluesky post should celebrate the poster short talk presentation winner @alessogozzo.bsky.social
at #RNA society of Sweden 😍🤩 proudest PhD sibling ever
May 6, 2025 at 10:50 PM
Reposted by Alessandro Gozzo
Our 🌷 May 🌷 issue is online with a broad range of article topics and formats!

In their Opinion article (on the cover, too!), @qichen-lab.bsky.social and colleagues describe the interactions between small ncRNAs and Toll-like receptors.

Find the issue here: www.cell.com/trends/bioch...
May 1, 2025 at 8:54 PM
Reposted by Alessandro Gozzo
Focus on gametogenesis

Our Reviews Editor, Laura Hankins, will be attending the GRC on Germinal Stem Cell Biology in Barcelona this week. To complement the meeting, we have put together a collection of review-type and Research Articles on this topic: journals.biologists.com/collection/2...
April 28, 2025 at 8:51 AM
Reposted by Alessandro Gozzo
Nutritional Trade-Offs in Drosophila melanogaster
#Drosophila
Nutritional Trade-Offs in Drosophila melanogaster #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
April 26, 2025 at 8:23 PM
Reposted by Alessandro Gozzo
DROSOPHILA: THE CENTURY-LONG FLIGHT FROM THE WILD TO THE PATIENT
#Drosophila
DROSOPHILA: THE CENTURY-LONG FLIGHT FROM THE WILD TO THE PATIENT #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
April 25, 2025 at 11:23 AM
Reposted by Alessandro Gozzo
Exciting news! Our latest work in the Nicola Iovino Lab, “Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis,” is now published in Nature Communications!
www.nature.com/articles/s41...
Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis - Nature Communications
Germ layer specification during zygotic genome activation is regulated by chromatin state. Here, the authors use single-cell multiome profiling in Drosophila to show that H3K27me3 and H3K27ac at cis-r...
www.nature.com
April 14, 2025 at 7:48 PM
Reposted by Alessandro Gozzo
Metabolism shapes life
EMBL Barcelona & @mpi-cbg.de researchers reveal how glycolysis drives early embryonic cell decisions.

The studies, published in Cell Stem Cell (@cp-cellstemcell.bsky.social), uncover the instructive potential of glycolysis.

www.embl.org/news/science...
April 16, 2025 at 3:20 PM
Reposted by Alessandro Gozzo
The Precision Omics Initiative Sweden (PROMISE) is a groundbreaking national effort designed to bridge the gap between research and healthcare. 🧪

Read all about it and hear from e.g. @tuuliel.bsky.social
www.scilifelab.se/news/new-swe...

#PrecisionMedicine.
New Swedish Initiative to Integrate Research and Healthcare
A groundbreaking national initiative, Precision Omics Initiative Sweden (PROMISE), aims to connect research with healthcare and establish Sweden as a world leader in data-driven precision medicine. Th...
www.scilifelab.se
April 8, 2025 at 9:39 AM
Reposted by Alessandro Gozzo
'Bluesky has overtaken its flailing rival X in hosting posts related to new academic research, indicating the platform is fast becoming the go-to place for scholars to share their work.'
X’s dominance ‘over’ as Bluesky becomes new hub for research
Data indicates more scholars turning to alternative social media site to post about their work after Elon Musk’s Twitter takeover
www.timeshighereducation.com
April 9, 2025 at 7:14 AM