Alejandro G. Castro Scalise
alejandrcastro.bsky.social
Alejandro G. Castro Scalise
@alejandrcastro.bsky.social
I shoot lasers at brains 🔬🧠
Reposted by Alejandro G. Castro Scalise
The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology.
Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available.

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June 5, 2025 at 8:36 PM
Reposted by Alejandro G. Castro Scalise
Tomaso Poggio gives the EBSA Keynote: The Race to Understand Intelligence  A personal perspective: intelligence and Biophysics

Proudly sponsored by Biophysical Society
June 30, 2025 at 4:48 PM
Reposted by Alejandro G. Castro Scalise
All-optical mapping of calcium in neuronal dendrites using CapChR2 and red-light emitting calcium reporter. Consistent with previous results showing ~50-fold slower diffusion of calcium compared to bulk water. Interesting to see this approach develop further!

www.sciencedirect.com/science/arti...
All-optical mapping of Ca2+ transport and homeostasis in dendrites
Calcium mediates many important signals in dendrites. However, the basic transport properties of calcium in dendrites have been difficult to measure: …
www.sciencedirect.com
January 7, 2025 at 11:35 AM
Reposted by Alejandro G. Castro Scalise
MD simulations of K+ ions permeation through the MthK potassium channel, done at +150 mV. We developed and applied optimized ion parameters within the Electronic Continuum Correction (ECC) framework. The simulated current quantitatively matches the experimental one.

www.biorxiv.org/content/10.1...
November 21, 2024 at 8:12 AM